Papers associated with tail (and kcnh1)

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	Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR., Sempou E., Nat Commun. November 5, 2022; 13 (1): 6681.
	External Cd2+ and protons activate the hyperpolarization-gated K+ channel KAT1 at the voltage sensor., Zhou Y., J Gen Physiol. January 4, 2021; 153 (1):
	Chlorpromazine binding to the PAS domains uncovers the effect of ligand modulation on EAG channel activity., Wang ZJ., J Biol Chem. March 27, 2020; 295 (13): 4114-4123.
	Regulation of Eag1 gating by its intracellular domains., Whicher JR., Elife. September 6, 2019; 8
	Identification of undecylenic acid as EAG channel inhibitor using surface plasmon resonance-based screen of KCNH channels., Wang ZJ., BMC Pharmacol Toxicol. July 17, 2019; 20 (1): 42.
	Bipolar switching by HCN voltage sensor underlies hyperpolarization activation., Cowgill J., Proc Natl Acad Sci U S A. January 8, 2019; 116 (2): 670-678.
	Dynamic rearrangement of the intrinsic ligand regulates KCNH potassium channels., Dai G., J Gen Physiol. April 2, 2018; 150 (4): 625-635.
	Molecular mechanism of voltage-dependent potentiation of KCNH potassium channels., Dai G., Elife. April 27, 2017; 6
	Calmodulin Regulates Human Ether à Go-Go 1 (hEAG1) Potassium Channels through Interactions of the Eag Domain with the Cyclic Nucleotide Binding Homology Domain., Lörinczi E., J Biol Chem. August 19, 2016; 291 (34): 17907-18.
	Mitragynine and its potential blocking effects on specific cardiac potassium channels., Tay YL., Toxicol Appl Pharmacol. August 15, 2016; 305 22-39.
	HPLC-Based Activity Profiling for hERG Channel Inhibitors in the South African Medicinal Plant Galenia africana., Du K., Planta Med. August 1, 2015; 81 (12-13): 1154-62.
	Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes., Liu QN., PLoS One. April 22, 2015; 10 (4): e0123951.
	Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels., Cristofori-Armstrong B., Sci Rep. January 12, 2015; 5 14763.
	Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy., Simons C., Nat Genet. January 1, 2015; 47 (1): 73-7.
	Up-regulation of hERG K⁺ channels by B-RAF., Pakladok T., PLoS One. January 1, 2014; 9 (1): e87457.
	The Eag domain regulates the voltage-dependent inactivation of rat Eag1 K+ channels., Lin TF., PLoS One. January 1, 2014; 9 (10): e110423.
	AMP-activated protein kinase regulates hERG potassium channel., Almilaji A., Pflugers Arch. November 1, 2013; 465 (11): 1573-82.
	Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel., Park MH., J Pharmacol Sci. September 20, 2013; 123 (1): 67-77.
	External pH modulates EAG superfamily K+ channels through EAG-specific acidic residues in the voltage sensor., Kazmierczak M., J Gen Physiol. June 1, 2013; 141 (6): 721-35.
	Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels., de la Peña P., Biochem J. May 1, 2013; 451 (3): 463-74.
	Flavonoid regulation of EAG1 channels., Carlson AE., J Gen Physiol. March 1, 2013; 141 (3): 347-58.
	Block of hERG K+ channel and prolongation of action potential duration by fluphenazine at submicromolar concentration., Hong HK., Eur J Pharmacol. February 28, 2013; 702 (1-3): 165-73.
	The eag domain regulates hERG channel inactivation gating via a direct interaction., Gustina AS., J Gen Physiol. February 1, 2013; 141 (2): 229-41.
	Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1., Aidery P., Gene. December 10, 2012; 511 (1): 26-33.
	Kcnh1 voltage-gated potassium channels are essential for early zebrafish development., Stengel R., J Biol Chem. October 12, 2012; 287 (42): 35565-35575.
	Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels., Tan PS., J Gen Physiol. September 1, 2012; 140 (3): 293-306.
	Identification and functional characterization of the novel human ether-a-go-go-related gene (hERG) R744P mutant associated with hereditary long QT syndrome 2., Aidery P., Biochem Biophys Res Commun. February 24, 2012; 418 (4): 830-5.
	Effects of the histamine H(1) receptor antagonist hydroxyzine on hERG K(+) channels and cardiac action potential duration., Lee BH., Acta Pharmacol Sin. September 1, 2011; 32 (9): 1128-37.
	Ginsenoside Rg(3) decelerates hERG K(+) channel deactivation through Ser631 residue interaction., Choi SH., Eur J Pharmacol. August 1, 2011; 663 (1-3): 59-67.
	Differential effects of ginsenoside metabolites on HERG k channel currents., Choi SH., J Ginseng Res. June 1, 2011; 35 (2): 191-9.
	Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore opening., Es-Salah-Lamoureux Z., PLoS One. May 3, 2010; 5 (5): e10876.
	Transfer of ion binding site from ether-a-go-go to Shaker: Mg2+ binds to resting state to modulate channel opening., Lin MC., J Gen Physiol. May 1, 2010; 135 (5): 415-31.
	Block of the human ether-a-go-go-related gene (hERG) K+ channel by the antidepressant desipramine., Hong HK., Biochem Biophys Res Commun. April 9, 2010; 394 (3): 536-41.
	Inhibition of the human ether-a-go-go-related gene (HERG) K+ channels by Lindera erythrocarpa., Hong HK., J Korean Med Sci. December 1, 2009; 24 (6): 1089-98.
	A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels., Gustina AS., Proc Natl Acad Sci U S A. August 4, 2009; 106 (31): 13082-7.
	Block of HERG k channel by classic histamine h(1) receptor antagonist chlorpheniramine., Hong HK., Korean J Physiol Pharmacol. June 1, 2009; 13 (3): 215-20.
	Blockade of the human ether-a-go-go-related gene potassium channel by ketanserin., Tu DN., Sheng Li Xue Bao. August 25, 2008; 60 (4): 525-34.
	Maprotiline block of the human ether-a-go-go-related gene (HERG) K+ channel., Jo SH., Arch Pharm Res. April 1, 2007; 30 (4): 453-60.
	Structural requirements of human ether-a-go-go-related gene channels for block by bupivacaine., Siebrands CC., Anesthesiology. March 1, 2007; 106 (3): 523-31.
	Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine., Lee SY., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.
	Chemical modification of the human ether-a-go-go-related gene (HERG) K+ current by the amino-group reagent trinitrobenzene sulfonic acid., Jo SH., Arch Pharm Res. April 1, 2006; 29 (4): 310-7.
	The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a-go-go related gene currents in Xenopus oocytes., Yamada M., Anesth Analg. January 1, 2006; 102 (1): 98-103.
	Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643)., Hansen RS., Mol Pharmacol. January 1, 2006; 69 (1): 266-77.
	Inhibitory effect of rhynchophylline on human ether-a-go-go related gene channel., Gui L., Sheng Li Xue Bao. October 25, 2005; 57 (5): 648-52.
	Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine., Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.
	A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels., Lin C., Am J Ther. January 1, 2005; 12 (4): 328-36.
	Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels., Craven KB., J Gen Physiol. December 1, 2004; 124 (6): 663-77.
	Gating charges in the activation and inactivation processes of the HERG channel., Zhang M., J Gen Physiol. December 1, 2004; 124 (6): 703-18.
	Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents., Gessner G., Mol Pharmacol. May 1, 2004; 65 (5): 1120-9.
	Negative charges in the transmembrane domains of the HERG K channel are involved in the activation- and deactivation-gating processes., Liu J., J Gen Physiol. June 1, 2003; 121 (6): 599-614.

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