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Summary Anatomy Item Literature (4863) Expression Attributions Wiki
XB-ANAT-511

Papers associated with nerve (and kcnh2)

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Regulation of human cardiac potassium channels by full-length KCNE3 and KCNE4., Abbott GW., Sci Rep. December 6, 2016; 6 38412.              


Blocking of the human ether-à-go-go-related gene channel by imatinib mesylate., Dong Q., Biol Pharm Bull. January 1, 2013; 36 (2): 268-75.


Recombinant expression of the toxic peptide ErgTx1 and role of Met35 on its stability and function., Jimenez-Vargas JM., Peptides. March 1, 2011; 32 (3): 560-7.


Response of i(kr) and HERG currents to the antipsychotics tiapride and sulpiride., Jo SH., Korean J Physiol Pharmacol. October 1, 2010; 14 (5): 305-10.


Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine., Obers S., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2010; 381 (5): 385-400.


Inhibition of the human ether-a-go-go-related gene (HERG) K+ channels by Lindera erythrocarpa., Hong HK., J Korean Med Sci. December 1, 2009; 24 (6): 1089-98.            


H(1) antihistamine drug promethazine directly blocks hERG K(+) channel., Jo SH., Pharmacol Res. November 1, 2009; 60 (5): 429-37.


Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures., Keller DI., Can J Cardiol. August 1, 2009; 25 (8): 455-62.


Differential modulation of cardiac potassium channels by Grb adaptor proteins., Ureche ON., Biochem Biophys Res Commun. June 19, 2009; 384 (1): 28-31.


Discovery of a novel activator of KCNQ1-KCNE1 K channel complexes., Mruk K., PLoS One. January 1, 2009; 4 (1): e4236.          


Selective noradrenaline reuptake inhibitor atomoxetine directly blocks hERG currents., Scherer D., Br J Pharmacol. January 1, 2009; 156 (2): 226-36.


The effects of chiral isolates of methadone on the cardiac potassium channel IKr., Lin C., Cardiology. January 1, 2009; 113 (1): 59-65.


Extracellular potassium dependency of block of HERG by quinidine and cisapride is primarily determined by the permeant ion and not by inactivation., Barrows B., Channels (Austin). January 1, 2009; 3 (4): 239-48.


Papaverine, a vasodilator, blocks the pore of the HERG channel at submicromolar concentration., Kim YJ., J Cardiovasc Pharmacol. December 1, 2008; 52 (6): 485-93.


[Analysis and analyzing mechanisms of HERG channel kinetics]., Wang X., Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. October 1, 2008; 25 (5): 1068-73.


Clomipramine block of the hERG K+ channel: accessibility to F656 and Y652., Jo SH., Eur J Pharmacol. September 11, 2008; 592 (1-3): 19-25.


Electropharmacological properties of telmisartan in blocking hKv1.5 and HERG potassium channels expressed on Xenopus laevis oocytes., Tu DN., Acta Pharmacol Sin. August 1, 2008; 29 (8): 913-22.


Inhibition of cardiac hERG potassium channels by tetracyclic antidepressant mianserin., Scherer D., Naunyn Schmiedebergs Arch Pharmacol. July 1, 2008; 378 (1): 73-83.


C101, a novel 4-amino-piperidine derivative selectively blocks N-type calcium channels., Zhang S., Eur J Pharmacol. June 10, 2008; 587 (1-3): 42-7.


Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels., Cuypers E., Toxicon. May 1, 2008; 51 (6): 974-83.


Mutational analysis of block and facilitation of HERG current by a class III anti-arrhythmic agent, nifekalant., Hosaka Y., Channels (Austin). January 1, 2007; 1 (3): 198-208.


Blockade of HERG human K+ channel and IKr of guinea pig cardiomyocytes by prochlorperazine., Kim MD., Eur J Pharmacol. August 21, 2006; 544 (1-3): 82-90.


Atypical tetracyclic antidepressant maprotiline is an antagonist at cardiac hERG potassium channels., Kiesecker C., Naunyn Schmiedebergs Arch Pharmacol. June 1, 2006; 373 (3): 212-20.


Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels., Clarke CE., J Physiol. June 1, 2006; 573 (Pt 2): 291-304.


Molecular determinants of HERG channel block., Kamiya K., Mol Pharmacol. May 1, 2006; 69 (5): 1709-16.


Chemical modification of the human ether-a-go-go-related gene (HERG) K+ current by the amino-group reagent trinitrobenzene sulfonic acid., Jo SH., Arch Pharm Res. April 1, 2006; 29 (4): 310-7.


Inhibition of cardiac HERG potassium channels by antidepressant maprotiline., Ferrer-Villada T., Eur J Pharmacol. February 15, 2006; 531 (1-3): 1-8.


Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs., Perry M., Mol Pharmacol. February 1, 2006; 69 (2): 509-19.


Mechanism of action of a novel human ether-a-go-go-related gene channel activator., Casis O., Mol Pharmacol. February 1, 2006; 69 (2): 658-65.


Block of HERG channels by berberine: mechanisms of voltage- and state-dependence probed with site-directed mutant channels., Rodriguez-Menchaca A., J Cardiovasc Pharmacol. January 1, 2006; 47 (1): 21-9.


The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a-go-go related gene currents in Xenopus oocytes., Yamada M., Anesth Analg. January 1, 2006; 102 (1): 98-103.


Inhibitory effect of rhynchophylline on human ether-a-go-go related gene channel., Gui L., Sheng Li Xue Bao. October 25, 2005; 57 (5): 648-52.


Interactions between charged residues in the transmembrane segments of the voltage-sensing domain in the hERG channel., Zhang M., J Membr Biol. October 1, 2005; 207 (3): 169-81.


Molecular mapping of a site for Cd2+-induced modification of human ether-à-go-go-related gene (hERG) channel activation., Fernandez D., J Physiol. September 15, 2005; 567 (Pt 3): 737-55.


Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine., Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.


The influence of extracellular acidosis on the effect of IKr blockers., Lin C., J Cardiovasc Pharmacol Ther. March 1, 2005; 10 (1): 67-76.


A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels., Lin C., Am J Ther. January 1, 2005; 12 (4): 328-36.


Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action., Kiesecker C., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 423-35.


Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine., Sánchez-Chapula JA., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2004; 370 (6): 484-91.


Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors., Thomas D., J Mol Med (Berl). December 1, 2004; 82 (12): 826-37.


Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome., Zehelein J., Biochim Biophys Acta. November 5, 2004; 1690 (3): 185-92.


The low-potency, voltage-dependent HERG blocker propafenone--molecular determinants and drug trapping., Witchel HJ., Mol Pharmacol. November 1, 2004; 66 (5): 1201-12.


Effects of the atrial antiarrhythmic drug AVE0118 on cardiac ion channels., Gögelein H., Naunyn Schmiedebergs Arch Pharmacol. September 1, 2004; 370 (3): 183-92.


Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone., Zitron E., Naunyn Schmiedebergs Arch Pharmacol. August 1, 2004; 370 (2): 146-56.


Ranolazine: ion-channel-blocking actions and in vivo electrophysiological effects., Schram G., Br J Pharmacol. August 1, 2004; 142 (8): 1300-8.


Structural determinants of HERG channel block by clofilium and ibutilide., Perry M., Mol Pharmacol. August 1, 2004; 66 (2): 240-9.


Probucol aggravates long QT syndrome associated with a novel missense mutation M124T in the N-terminus of HERG., Hayashi K., Clin Sci (Lond). August 1, 2004; 107 (2): 175-82.


Molecular basis of slow activation of the human ether-a-go-go related gene potassium channel., Subbiah RN., J Physiol. July 15, 2004; 558 (Pt 2): 417-31.


Activation properties of Kv4.3 channels: time, voltage and [K+]o dependence., Wang S., J Physiol. June 15, 2004; 557 (Pt 3): 705-17.


Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action., Thomas D., Br J Pharmacol. June 1, 2004; 142 (3): 485-94.

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