Papers associated with gabarap

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	A cycloartane glycoside derived from Actaea racemosa L. modulates GABAA receptors and induces pronounced sedation in mice., Strommer B, Khom S, Kastenberger I, Cicek SS, Stuppner H, Schwarzer C, Hering S., J Pharmacol Exp Ther. November 1, 2014; 351 (2): 234-42.
	Phenylalanine in the pore of the Erwinia ligand-gated ion channel modulates picrotoxinin potency but not receptor function., Thompson AJ, Alqazzaz M, Price KL, Weston DA, Lummis SC., Biochemistry. October 7, 2014; 53 (39): 6183-8.
	Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin., Eghorn LF, Hoestgaard-Jensen K, Kongstad KT, Bay T, Higgins D, Frølund B, Wellendorph P., Eur J Pharmacol. October 5, 2014; 740 570-7.
	Moderate concentrations of 4-O-methylhonokiol potentiate GABAA receptor currents stronger than honokiol., Baur R, Schuehly W, Sigel E., Biochim Biophys Acta. October 1, 2014; 1840 (10): 3017-21.
	Phosphatidylinositol 4,5-bisphosphate depletion fails to affect neurosteroid modulation of GABAA receptor function., Mennerick S, Taylor AA, Zorumski CF., Psychopharmacology (Berl). September 1, 2014; 231 (17): 3493-501.
	11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors., Chen ZW, Wang C, Krishnan K, Manion BD, Hastings R, Bracamontes J, Taylor A, Eaton MM, Zorumski CF, Steinbach JH, Akk G, Mennerick S, Covey DF, Evers AS., Psychopharmacology (Berl). September 1, 2014; 231 (17): 3479-91.
	Competitive antagonism of insect GABA receptors by 4-substituted 5-(4-piperidyl)-3-isothiazolols., Liu G, Furuta K, Nakajima H, Ozoe F, Ozoe Y., Bioorg Med Chem. September 1, 2014; 22 (17): 4637-45.
	Modulation of the human ρ1 GABAA receptor by inhibitory steroids., Eaton MM, Lim YB, Covey DF, Akk G., Psychopharmacology (Berl). September 1, 2014; 231 (17): 3467-78.
	Relative positioning of classical benzodiazepines to the γ2-subunit of GABAA receptors., Middendorp SJ, Hurni E, Schönberger M, Stein M, Pangerl M, Trauner D, Sigel E., ACS Chem Biol. August 15, 2014; 9 (8): 1846-53.
	Engineering a light-regulated GABAA receptor for optical control of neural inhibition., Lin WC, Davenport CM, Mourot A, Vytla D, Smith CM, Medeiros KA, Chambers JJ, Kramer RH., ACS Chem Biol. July 18, 2014; 9 (7): 1414-9.
	Esters of valerenic acid as potential prodrugs., Hintersteiner J, Haider M, Luger D, Schwarzer C, Reznicek G, Jäger W, Khom S, Mihovilovic MD, Hering S., Eur J Pharmacol. July 15, 2014; 735 123-31.
	Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives., Schöffmann A, Wimmer L, Goldmann D, Khom S, Hintersteiner J, Baburin I, Schwarz T, Hintersteininger M, Pakfeifer P, Oufir M, Hamburger M, Erker T, Ecker GF, Mihovilovic MD, Hering S., J Med Chem. July 10, 2014; 57 (13): 5602-19.
	Differential modulation of GABA(A) receptor function by aryl pyrazoles., Mascia MP, Ledda G, Orrù A, Marongiu A, Loriga G, Maciocco E, Biggio G, Ruiu S., Eur J Pharmacol. June 15, 2014; 733 1-6.
	Modulation of ionotropic GABA receptors by 6-methoxyflavanone and 6-methoxyflavone., Hall BJ, Karim N, Chebib M, Johnston GA, Hanrahan JR., Neurochem Res. June 1, 2014; 39 (6): 1068-78.
	Alcohol selectivity of β3-containing GABAA receptors: evidence for a unique extracellular alcohol/imidazobenzodiazepine Ro15-4513 binding site at the α+β- subunit interface in αβ3δ GABAA receptors., Wallner M, Hanchar HJ, Olsen RW., Neurochem Res. June 1, 2014; 39 (6): 1118-26.
	Unexpected Properties of δ-Containing GABAA Receptors in Response to Ligands Interacting with the α+ β- Site., Mirheydari P, Ramerstorfer J, Varagic Z, Scholze P, Wimmer L, Mihovilovic MM, Sieghart W, Ernst M., Neurochem Res. June 1, 2014; 39 (6): 1057-1067.
	Identifying barbiturate binding sites in a nicotinic acetylcholine receptor with [3H]allyl m-trifluoromethyldiazirine mephobarbital, a photoreactive barbiturate., Hamouda AK, Stewart DS, Chiara DC, Savechenkov PY, Bruzik KS, Cohen JB., Mol Pharmacol. May 1, 2014; 85 (5): 735-46.
	An intracellular redox sensor for reactive oxygen species at the M3-M4 linker of GABAA ρ1 receptors., Beltrán González AN, Gasulla J, Calvo DJ., Br J Pharmacol. May 1, 2014; 171 (9): 2291-9.
	GABA(A) receptor modulation by terpenoids from Sideritis extracts., Kessler A, Sahin-Nadeem H, Lummis SC, Weigel I, Pischetsrieder M, Buettner A, Villmann C., Mol Nutr Food Res. April 1, 2014; 58 (4): 851-62.
	HPLC-based activity profiling for GABAA receptor modulators in Adenocarpus cincinnatus., Rueda DC, De Mieri M, Hering S, Hamburger M., J Nat Prod. March 28, 2014; 77 (3): 640-9.
	Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: the approximated activation of receptor subtypes may explain behavioral effects., Obradović ALj, Joksimović S, Poe MM, Ramerstorfer J, Varagic Z, Namjoshi O, Batinić B, Radulović T, Marković B, Roth BL, Sieghart W, Cook JM, Savić MM., Dev Biol. March 20, 2014; 1554 36-48.
	The pharmacology of cyclopropyl-methoxycarbonyl metomidate: a comparison with propofol., Ge R, Pejo E, Gallin H, Jeffrey S, Cotten JF, Raines DE., Anesth Analg. March 1, 2014; 118 (3): 563-7.
	Generation of recombinant antibodies to rat GABAA receptor subunits by affinity selection on synthetic peptides., Koduvayur SP, Gussin HA, Parthasarathy R, Hao Z, Kay BK, Pepperberg DR., PLoS One. February 19, 2014; 9 (2): e87964.
	Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators., Rueda DC, Schöffmann A, De Mieri M, Raith M, Jähne EA, Hering S, Hamburger M., Bioorg Med Chem. February 15, 2014; 22 (4): 1276-84.
	Cloning and characterization of the ionotropic GABA receptor subunit ρ1 from pig (Sus scrofa)., Reyes-Ruiz JM, Limon A, Miledi R., Neurosci Lett. January 13, 2014; 558 78-81.
	Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone., Qian M, Krishnan K, Kudova E, Li P, Manion BD, Taylor A, Elias G, Akk G, Evers AS, Zorumski CF, Mennerick S, Covey DF., J Med Chem. January 9, 2014; 57 (1): 171-90.
	Mutations at beta N265 in γ-aminobutyric acid type A receptors alter both binding affinity and efficacy of potent anesthetics., Stewart DS, Pierce DW, Hotta M, Stern AT, Forman SA., PLoS One. January 1, 2014; 9 (10): e111470.
	GABAA receptors containing ρ1 subunits contribute to in vivo effects of ethanol in mice., Blednov YA, Benavidez JM, Black M, Leiter CR, Osterndorff-Kahanek E, Johnson D, Borghese CM, Hanrahan JR, Johnston GA, Chebib M, Harris RA., PLoS One. January 1, 2014; 9 (1): e85525.
	Novel analogues of chlormethiazole are neuroprotective in four cellular models of neurodegeneration by a mechanism with variable dependence on GABA(A) receptor potentiation., Vandevrede L, Tavassoli E, Luo J, Qin Z, Yue L, Pepperberg DR, Thatcher GR., Br J Pharmacol. January 1, 2014; 171 (2): 389-402.
	Phytochemical profiling of Curcuma kwangsiensis rhizome extract, and identification of labdane diterpenoids as positive GABAA receptor modulators., Schramm A, Ebrahimi SN, Raith M, Zaugg J, Rueda DC, Hering S, Hamburger M., Phytochemistry. December 1, 2013; 96 318-29.
	Cysteine substitutions define etomidate binding and gating linkages in the α-M1 domain of γ-aminobutyric acid type A (GABAA) receptors., Stewart DS, Hotta M, Li GD, Desai R, Chiara DC, Olsen RW, Forman SA., J Biol Chem. October 18, 2013; 288 (42): 30373-30386.
	Fractalkine/CX3CL1 modulates GABAA currents in human temporal lobe epilepsy., Roseti C, Fucile S, Lauro C, Martinello K, Bertollini C, Esposito V, Mascia A, Catalano M, Aronica E, Limatola C, Palma E., Epilepsia. October 1, 2013; 54 (10): 1834-44.
	The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors., Hoestgaard-Jensen K, O'Connor RM, Dalby NO, Simonsen C, Finger BC, Golubeva A, Hammer H, Bergmann ML, Kristiansen U, Krogsgaard-Larsen P, Bräuner-Osborne H, Ebert B, Frølund B, Cryan JF, Jensen AA., Br J Pharmacol. October 1, 2013; 170 (4): 919-32.
	Do N-arachidonyl-glycine (NA-glycine) and 2-arachidonoyl glycerol (2-AG) share mode of action and the binding site on the β2 subunit of GABAA receptors?, Baur R, Gertsch J, Sigel E., PeerJ. September 10, 2013; 1 e149.
	GABAA receptor modulation by piperine and a non-TRPV1 activating derivative., Khom S, Strommer B, Schöffmann A, Hintersteiner J, Baburin I, Erker T, Schwarz T, Schwarzer C, Zaugg J, Hamburger M, Hering S., Biochem Pharmacol. June 15, 2013; 85 (12): 1827-36.
	New insights in endogenous modulation of ligand-gated ion channels: histamine is an inverse agonist at strychnine sensitive glycine receptors., Kletke O, Sergeeva OA, Lorenz P, Oberland S, Meier JC, Hatt H, Gisselmann G., Eur J Pharmacol. June 15, 2013; 710 (1-3): 59-66.
	State-dependent etomidate occupancy of its allosteric agonist sites measured in a cysteine-substituted GABAA receptor., Stewart DS, Hotta M, Desai R, Forman SA., Mol Pharmacol. June 1, 2013; 83 (6): 1200-8.
	Subtype selectivity of α+β- site ligands of GABAA receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors., Varagic Z, Ramerstorfer J, Huang S, Rallapalli S, Sarto-Jackson I, Cook J, Sieghart W, Ernst M., Br J Pharmacol. May 1, 2013; 169 (2): 384-99.
	Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface., Varagic Z, Wimmer L, Schnürch M, Mihovilovic MD, Huang S, Rallapalli S, Cook JM, Mirheydari P, Ecker GF, Sieghart W, Ernst M., Br J Pharmacol. May 1, 2013; 169 (2): 371-83.
	Benzodiazepine-induced spatial learning deficits in rats are regulated by the degree of modulation of α1 GABA(A) receptors., Joksimović S, Divljaković J, Van Linn ML, Varagic Z, Brajković G, Milinković MM, Yin W, Timić T, Sieghart W, Cook JM, Savić MM., Eur Neuropsychopharmacol. May 1, 2013; 23 (5): 390-9.
	Ginsenoside Rg₃ regulates GABAA receptor channel activity: involvement of interaction with the γ₂ subunit., Lee BH, Kim HJ, Chung L, Nah SY., Eur J Pharmacol. April 5, 2013; 705 (1-3): 119-25.
	Potency of GABA at human recombinant GABA(A) receptors expressed in Xenopus oocytes: a mini review., Karim N, Wellendorph P, Absalom N, Johnston GA, Hanrahan JR, Chebib M., Amino Acids. April 1, 2013; 44 (4): 1139-49.
	Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC)., Spurny R, Billen B, Howard RJ, Brams M, Debaveye S, Price KL, Weston DA, Strelkov SV, Tytgat J, Bertrand S, Bertrand D, Lummis SCR, Ulens C., J Biol Chem. March 22, 2013; 288 (12): 8355-8364.
	Quantum dot conjugates of GABA and muscimol: binding to α1β2γ2 and ρ1 GABA(A) receptors., Gussin HA, Tomlinson ID, Cao D, Qian H, Rosenthal SJ, Pepperberg DR., ACS Chem Neurosci. March 20, 2013; 4 (3): 435-43.
	Additive inhibition of human α1β2γ2 GABAA receptors by mixtures of commonly used drugs of abuse., Hondebrink L, Tan S, Hermans E, van Kleef RG, Meulenbelt J, Westerink RH., Neurotoxicology. March 1, 2013; 35 23-9.
	Partial agonism of taurine at gamma-containing native and recombinant GABAA receptors., Kletke O, Gisselmann G, May A, Hatt H, Sergeeva OA., PLoS One. January 1, 2013; 8 (4): e61733.
	Macroscopic kinetics of pentameric ligand gated ion channels: comparisons between two prokaryotic channels and one eukaryotic channel., Laha KT, Ghosh B, Czajkowski C., PLoS One. January 1, 2013; 8 (11): e80322.
	The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor., Thompson AJ, Alqazzaz M, Ulens C, Lummis SC., Neuropharmacology. September 1, 2012; 63 (4): 761-7.
	Negative modulation of GABAA α5 receptors by RO4938581 attenuates discrete sub-chronic and early postnatal phencyclidine (PCP)-induced cognitive deficits in rats., Redrobe JP, Elster L, Frederiksen K, Bundgaard C, de Jong IE, Smith GP, Bruun AT, Larsen PH, Didriksen M., Psychopharmacology (Berl). June 1, 2012; 221 (3): 451-68.
	A single amino acid determines the toxicity of Ginkgo biloba extracts., Thompson AJ, McGonigle I, Duke R, Johnston GA, Lummis SC., FASEB J. May 1, 2012; 26 (5): 1884-91.

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