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Summary Expression Phenotypes Gene Literature (677) GO Terms (3) Nucleotides (94) Proteins (51) Interactants (1024) Wiki
XB-GENEPAGE-485904

Papers associated with ins



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Connective-tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex., Mercurio S, Latinkic B, Itasaki N, Krumlauf R, Smith JC., Development. May 1, 2004; 131 (9): 2137-47.                    


Regulation of the voltage gated K+ channel Kv1.3 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid inducible kinase SGK1., Henke G, Maier G, Wallisch S, Boehmer C, Lang F., J Cell Physiol. May 1, 2004; 199 (2): 194-9.


Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes., Gloyn AL, Pearson ER, Antcliff JF, Proks P, Bruining GJ, Slingerland AS, Howard N, Srinivasan S, Silva JM, Molnes J, Edghill EL, Frayling TM, Temple IK, Mackay D, Shield JP, Sumnik Z, van Rhijn A, Wales JK, Clark P, Gorman S, Aisenberg J, Ellard S, Njølstad PR, Ashcroft FM, Hattersley AT., N Engl J Med. April 29, 2004; 350 (18): 1838-49.


An effector peptide from glutathione-S-transferase-pi strongly and selectively blocks mitotic signaling by oncogenic ras-p21., Chie L, Adler V, Friedman FK, Chung D, Pincus MR., Protein J. April 1, 2004; 23 (3): 235-8.


Loop domain peptides from the SOS ras-guanine nucleotide exchange protein, identified from molecular dynamics calculations, strongly inhibit ras signaling., Chie L, Friedman FK, Duncan T, Chen JM, Chung D, Pincus M., Protein J. April 1, 2004; 23 (3): 229-34.


Characterization of insulin-like growth factor-free interaction between insulin-like growth factor binding protein 3 and acid labile subunit expressed from Xenopus oocytes., Choi KY, Kyung YJ, Lee CY, Lee CY, Lee DH., J Biochem Mol Biol. March 31, 2004; 37 (2): 153-8.


Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity., Bichet D, Lin YF, Ibarra CA, Huang CS, Yi BA, Jan YN, Jan LY., Proc Natl Acad Sci U S A. March 30, 2004; 101 (13): 4441-6.


Inhibition of ATP-sensitive K+ channels by taurine through a benzamido-binding site on sulfonylurea receptor 1., Park EJ, Bae JH, Kim SY, Lim JG, Baek WK, Kwon TK, Suh SI, Park JW, Lee IK, Ashcroft FM, Song DK., Biochem Pharmacol. March 15, 2004; 67 (6): 1089-96.


Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity., Nozawa T, Sugiura S, Nakajima M, Goto A, Yokoi T, Nezu J, Tsuji A, Tamai I., Drug Metab Dispos. March 1, 2004; 32 (3): 291-4.


Ca2+-dependent redox modulation of SERCA 2b by ERp57., Li Y, Camacho P., J Cell Biol. January 5, 2004; 164 (1): 35-46.                    


Mammary tumor induction in transgenic mice expressing an RNA-binding protein., Tessier CR, Doyle GA, Clark BA, Pitot HC, Ross J., Cancer Res. January 1, 2004; 64 (1): 209-14.


Progesterone and insulin stimulation of CPEB-dependent polyadenylation is regulated by Aurora A and glycogen synthase kinase-3., Sarkissian M, Mendez R, Richter JD., Genes Dev. January 1, 2004; 18 (1): 48-61.


Pancreatic protein disulfide isomerase (XPDIp) is an early marker for the exocrine lineage of the developing pancreas in Xenopus laevis embryos., Afelik S, Chen Y, Pieler T., Gene Expr Patterns. January 1, 2004; 4 (1): 71-6.    


Mouse MafA, homologue of zebrafish somite Maf 1, contributes to the specific transcriptional activity through the insulin promoter., Kajihara M, Sone H, Amemiya M, Katoh Y, Isogai M, Shimano H, Yamada N, Takahashi S., Biochem Biophys Res Commun. December 19, 2003; 312 (3): 831-42.


Potentiation of quantal secretion by insulin-like growth factor-1 at developing motoneurons in Xenopus cell culture., Liou JC, Tsai FZ, Ho SY., J Physiol. December 15, 2003; 553 (Pt 3): 719-28.


Xp42(Mpk1) activation is not required for germinal vesicle breakdown but for Raf complete phosphorylation in insulin-stimulated Xenopus oocytes., Baert F, Bodart JF, Bocquet-Muchembled B, Lescuyer-Rousseau A, Vilain JP., J Biol Chem. December 12, 2003; 278 (50): 49714-20.


The PIR domain of Grb14 is an intrinsically unstructured protein: implication in insulin signaling., Moncoq K, Broutin I, Larue V, Perdereau D, Cailliau K, Browaeys-Poly E, Burnol AF, Ducruix A., FEBS Lett. November 20, 2003; 554 (3): 240-6.


Oncogenic and activated wild-type ras-p21 proteins induce different isoforms of protein kinase C in mitogenic signal transduction., Chie L, Qu Y, Chung D, Boutjdir M, Pincus MR., J Protein Chem. November 1, 2003; 22 (7-8): 625-9.


Subunit contributions to phosphorylation-dependent modulation of bovine rod cyclic nucleotide-gated channels., Molokanova E, Krajewski JL, Satpaev D, Luetje CW, Kramer RH., J Physiol. October 15, 2003; 552 (Pt 2): 345-56.


Isolation and characterization of a novel human thioredoxin-like gene hTLP19 encoding a secretory protein., Liu F, Rong YP, Zeng LC, Zhang X, Han ZG., Gene. October 2, 2003; 315 71-8.


Potent and selective activation of the pancreatic beta-cell type K(ATP) channel by two novel diazoxide analogues., Dabrowski M, Larsen T, Ashcroft FM, Bondo Hansen J, Wahl P., Diabetologia. October 1, 2003; 46 (10): 1375-82.


Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid-inducible kinase isoforms SGK1/3 and protein kinase B., Boehmer C, Henke G, Schniepp R, Palmada M, Rothstein JD, Bröer S, Lang F., J Neurochem. September 1, 2003; 86 (5): 1181-8.


Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes., Rogers S, Chandler JD, Clarke AL, Petrou S, Best JD., Biochem Biophys Res Commun. August 29, 2003; 308 (3): 422-6.


Inhibition of FGF receptor signalling in Xenopus oocytes: differential effect of Grb7, Grb10 and Grb14., Cailliau K, Le Marcis V, Béréziat V, Perdereau D, Cariou B, Vilain JP, Burnol AF, Browaeys-Poly E., FEBS Lett. July 31, 2003; 548 (1-3): 43-8.


Toward tissue-selective pancreatic B-cells KATP channel openers belonging to 3-alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-dioxides., de Tullio P, Becker B, Boverie S, Dabrowski M, Wahl P, Antoine MH, Somers F, Sebille S, Ouedraogo R, Hansen JB, Lebrun P, Pirotte B., J Med Chem. July 17, 2003; 46 (15): 3342-53.


Molecular cloning and characterization of an adaptor protein Shc isoform from Xenopus laevis oocytes., Chesnel F, Heligon C, Richard-Parpaillon L, Boujard D., Biol Cell. July 1, 2003; 95 (5): 311-20.


Insulin signaling inhibits the 5-HT2C receptor in choroid plexus via MAP kinase., Hurley JH, Zhang S, Bye LS, Marshall MS, DePaoli-Roach AA, Guan K, Fox AP, Yu L., BMC Neurosci. June 9, 2003; 4 10.        


Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling., Latinkic BV, Mercurio S, Bennett B, Hirst EM, Xu Q, Lau LF, Mohun TJ, Smith JC., Development. June 1, 2003; 130 (11): 2429-41.        


Insulin-stimulated trafficking of ENaC in renal cells requires PI 3-kinase activity., Blazer-Yost BL, Esterman MA, Vlahos CJ., Am J Physiol Cell Physiol. June 1, 2003; 284 (6): C1645-53.


Mouse system-N amino acid transporter, mNAT3, expressed in hepatocytes and regulated by insulin-activated and phosphoinositide 3-kinase-dependent signalling., Gu S, Langlais P, Liu F, Jiang JX., Biochem J. May 1, 2003; 371 (Pt 3): 721-31.


Quantification of phosphatidic acid and lysophosphatidic acid by HPLC with evaporative light-scattering detection., Holland WL, Stauter EC, Stith BJ., J Lipid Res. April 1, 2003; 44 (4): 854-8.


Serum and glucocorticoid inducible kinases in the regulation of the cardiac sodium channel SCN5A., Boehmer C, Wilhelm V, Palmada M, Wallisch S, Henke G, Brinkmeier H, Cohen P, Pieske B, Lang F., Cardiovasc Res. March 15, 2003; 57 (4): 1079-84.


Aquaglyceroporin AQP9: solute permeation and metabolic control of expression in liver., Carbrey JM, Gorelick-Feldman DA, Kozono D, Praetorius J, Nielsen S, Agre P., Proc Natl Acad Sci U S A. March 4, 2003; 100 (5): 2945-50.


Cell-autonomous and signal-dependent expression of liver and intestine marker genes in pluripotent precursor cells from Xenopus embryos., Chen Y, Chen Y, Jürgens K, Hollemann T, Claussen M, Ramadori G, Pieler T., Mech Dev. March 1, 2003; 120 (3): 277-88.                      


Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides., Reimann F, Dabrowski M, Jones P, Gribble FM, Ashcroft FM., J Physiol. February 15, 2003; 547 (Pt 1): 159-68.


Characterisation of new KATP-channel mutations associated with congenital hyperinsulinism in the Finnish population., Reimann F, Huopio H, Dabrowski M, Proks P, Gribble FM, Laakso M, Otonkoski T, Ashcroft FM., Diabetologia. February 1, 2003; 46 (2): 241-9.


Role of SGK in hormonal regulation of epithelial sodium channel in A6 cells., Alvarez de la Rosa D, Canessa CM., Am J Physiol Cell Physiol. February 1, 2003; 284 (2): C404-14.


Experimental conversion of liver to pancreas., Horb ME, Shen CN, Tosh D, Slack JM., Curr Biol. January 21, 2003; 13 (2): 105-15.    


Protein kinase B/Akt is essential for the insulin- but not progesterone-stimulated resumption of meiosis in Xenopus oocytes., Andersen CB, Sakaue H, Nedachi T, Kovacina KS, Clayberger C, Conti M, Roth RA., Biochem J. January 15, 2003; 369 (Pt 2): 227-38.


A protein methyl transferase, PRMT5, selectively blocks oncogenic ras-p21 mitogenic signal transduction., Chie L, Cook JR, Chung D, Hoffmann R, Yang Z, Kim Y, Pestka S, Pincus MR., Ann Clin Lab Sci. January 1, 2003; 33 (2): 200-7.


Differential selectivity of insulin secretagogues: mechanisms, clinical implications, and drug interactions., Gribble FM, Reimann F., J Diabetes Complications. January 1, 2003; 17 (2 Suppl): 11-5.


Inhibition of cromakalim-activated K+ current by ethanol in follicle-enclosed Xenopus oocytes., Oz M, Tchugunova Y, Dinc M., Naunyn Schmiedebergs Arch Pharmacol. January 1, 2003; 367 (1): 80-5.


Comparative peptidomics of the endocrine pancreas: islet hormones from the clawed frog Xenopus laevis and the red-bellied newt Cynops pyrrhogaster., Conlon JM, Kim JB, Johansson A, Kikuyama S., J Endocrinol. December 1, 2002; 175 (3): 769-77.


The adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase Czeta., Cariou B, Perdereau D, Cailliau K, Browaeys-Poly E, Béréziat V, Vasseur-Cognet M, Girard J, Burnol AF., Mol Cell Biol. October 1, 2002; 22 (20): 6959-70.


Inhibition of recombinant K(ATP) channels by the antidiabetic agents midaglizole, LY397364 and LY389382., Proks P, Treinies I, Mest HJ, Trapp S., Eur J Pharmacol. September 27, 2002; 452 (1): 11-9.


Characterization of two novel forms of the rat sulphonylurea receptor SUR1A2 and SUR1BDelta31., Gros L, Trapp S, Dabrowski M, Ashcroft FM, Bataille D, Blache P., Br J Pharmacol. September 1, 2002; 137 (1): 98-106.


Inhibition of ras-induced oocyte maturation by peptides from ras-p21 and GTPase activating protein (GAP) identified as being effector domains from molecular dynamics calculations., Friedman FK, Chie L, Chung D, Robinson R, Brandt-Rauf P, Yamaizumi Z, Pincus MR., J Protein Chem. July 1, 2002; 21 (5): 361-6.


Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes., Kanzaki M, Watson RT, Hou JC, Stamnes M, Saltiel AR, Pessin JE., Mol Biol Cell. July 1, 2002; 13 (7): 2334-46.


Zebrafish insulin-like growth factor-I receptor: molecular cloning and developmental expression., Ayaso E, Nolan CM, Byrnes L., Mol Cell Endocrinol. June 14, 2002; 191 (2): 137-48.


The 25-kDa synaptosome-associated protein (SNAP-25) binds and inhibits delayed rectifier potassium channels in secretory cells., Ji J, Tsuk S, Salapatek AM, Huang X, Chikvashvili D, Pasyk EA, Kang Y, Sheu L, Tsushima R, Diamant N, Trimble WS, Lotan I, Gaisano HY., J Biol Chem. June 7, 2002; 277 (23): 20195-204.

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