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Summary Expression Phenotypes Gene Literature (677) GO Terms (3) Nucleotides (94) Proteins (51) Interactants (1024) Wiki
XB-GENEPAGE-485904

Papers associated with ins



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The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery., Wiser O, Trus M, Hernández A, Renström E, Barg S, Rorsman P, Atlas D., Proc Natl Acad Sci U S A. January 5, 1999; 96 (1): 248-53.

The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding., Sharma A, Moore M, Marcora E, Lee JE, Qiu Y, Samaras S, Stein R., Mol Cell Biol. January 1, 1999; 19 (1): 704-13.

Acute suppression of inwardly rectifying Kir2.1 channels by direct tyrosine kinase phosphorylation., Wischmeyer E, Döring F, Karschin A., J Biol Chem. December 18, 1998; 273 (51): 34063-8.

Cloning of the Xenopus laevis aldolase C gene and analysis of its promoter function in developing Xenopus embryos and A6 cells., Yatsuki H, Outida M, Atsuchi Y, Mukai T, Shiokawa K, Hori K., Biochim Biophys Acta. November 8, 1998; 1442 (2-3): 199-217.                              

Complex history of a chromosomal paralogy region: insights from amphioxus aromatic amino acid hydroxylase genes and insulin-related genes., Patton SJ, Luke GN, Holland PW., Mol Biol Evol. November 1, 1998; 15 (11): 1373-80.

Synthesis and differentially regulated processing of proinsulin in developing chick pancreas, liver and neuroretina., Alarcón C, Serna J, Pérez-Villamil B, de Pablo F., FEBS Lett. October 9, 1998; 436 (3): 361-6.

Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA., Gribble FM, Proks P, Corkey BE, Ashcroft FM., J Biol Chem. October 9, 1998; 273 (41): 26383-7.

Gene and cDNA structures of flounder insulin-like growth factor-I (IGF-I): multiple mRNA species encode a single short mature IGF-I., Tanaka M, Taniguchi T, Yamamoto I, Sakaguchi K, Yoshizato H, Ohkubo T, Nakashima K., DNA Cell Biol. October 1, 1998; 17 (10): 859-68.

Different functional domains of GLUT2 glucose transporter are required for glucose affinity and substrate specificity., Wu L, Fritz JD, Powers AC., Endocrinology. October 1, 1998; 139 (10): 4205-12.

Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell K(ATP) channels., Gribble FM, Tucker SJ, Seino S, Ashcroft FM., Diabetes. September 1, 1998; 47 (9): 1412-8.

The role of maternal VegT in establishing the primary germ layers in Xenopus embryos., Zhang J, Houston DW, King ML, Payne C, Wylie C, Heasman J., Cell. August 21, 1998; 94 (4): 515-24.                

A novel insulin receptor substrate protein, xIRS-u, potentiates insulin signaling: functional importance of its pleckstrin homology domain., Ohan N, Bayaa M, Kumar P, Zhu L, Liu XJ., Mol Endocrinol. August 1, 1998; 12 (8): 1086-98.

4H-1,2,4-Pyridothiadiazine 1,1-dioxides and 2,3-dihydro-4H-1,2, 4-pyridothiadiazine 1,1-dioxides chemically related to diazoxide and cyclothiazide as powerful positive allosteric modulators of (R/S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors: design, synthesis, pharmacology, and structure-activity relationships., Pirotte B, Podona T, Diouf O, de Tullio P, Lebrun P, Dupont L, Somers F, Delarge J, Morain P, Lestage P, Lepagnol J, Spedding M., J Med Chem. July 30, 1998; 41 (16): 2946-59.

Protein kinase B/Akt induces resumption of meiosis in Xenopus oocytes., Andersen CB, Roth RA, Conti M., J Biol Chem. July 24, 1998; 273 (30): 18705-8.

A particle-receptor model for the insulin-induced closure of connexin43 channels., Homma N, Alvarado JL, Coombs W, Stergiopoulos K, Taffet SM, Lau AF, Delmar M., Circ Res. July 13, 1998; 83 (1): 27-32.

MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit., Gribble FM, Tucker SJ, Haug T, Ashcroft FM., Proc Natl Acad Sci U S A. June 9, 1998; 95 (12): 7185-90.

Inhibition of the ATP-sensitive potassium channel from mouse pancreatic beta-cells by surfactants., Smith PA, Proks P., Br J Pharmacol. June 1, 1998; 124 (3): 529-39.

Hormonal regulation of ENaCs: insulin and aldosterone., Blazer-Yost BL, Liu X, Helman SI., Am J Physiol. May 1, 1998; 274 (5): C1373-9.

An immunohistochemical and morphometric analysis of insulin, insulin-like growth factor I, glucagon, somatostatin, and PP in the development of the gastro-entero-pancreatic system of Xenopus laevis., Maake C, Hanke W, Reinecke M., Gen Comp Endocrinol. May 1, 1998; 110 (2): 182-95.                

Phosphatidylinositol 3-kinase activation is required for insulin-stimulated sodium transport in A6 cells., Record RD, Froelich LL, Vlahos CJ, Blazer-Yost BL., Am J Physiol. April 1, 1998; 274 (4): E611-7.

Organization of the human glucokinase regulator gene GCKR., Hayward BE, Dunlop N, Intody S, Leek JP, Markham AF, Warner JP, Bonthron DT., Genomics. April 1, 1998; 49 (1): 137-42.

Vasopressin-induced activation of protein kinase C in renal epithelial cells., Ali N, Kantachuvesiri S, Smallwood JI, Macala LJ, Isales C, Ji J, Reilly R, Hayslett JP., Biochim Biophys Acta. March 27, 1998; 1402 (2): 188-96.

Molecular cloning and characterization of Xenopus insulin-like growth factor-1 receptor: its role in mediating insulin-induced Xenopus oocyte maturation and expression during embryogenesis., Zhu L, Ohan N, Agazie Y, Cummings C, Farah S, Liu XJ., Endocrinology. March 1, 1998; 139 (3): 949-54.

A rho-associated protein kinase, ROKalpha, binds insulin receptor substrate-1 and modulates insulin signaling., Farah S, Agazie Y, Ohan N, Ngsee JK, Liu XJ., J Biol Chem. February 20, 1998; 273 (8): 4740-6.

Recombinant protein kinase C-gamma phorbol binding domain upon microinjection blocked insulin-induced maturation of Xenopus laevis oocytes., Pawelczyk T, Matecki A, Dettlaff A., FEBS Lett. February 13, 1998; 423 (1): 31-4.

Primary structure and functional expression of a novel non-selective cation channel., Suzuki M, Murata M, Ikeda M, Miyoshi T, Imai M., Biochem Biophys Res Commun. January 6, 1998; 242 (1): 191-6.

Small-molecule control of insulin and PDGF receptor signaling and the role of membrane attachment., Yang J, Symes K, Mercola M, Schreiber SL., Curr Biol. January 1, 1998; 8 (1): 11-8.

Potentiating effect of metformin on insulin-induced glucose uptake and glycogen metabolism with Xenopus oocytes., Detaille D, Wiernsperger N, Devos P., Diabetologia. January 1, 1998; 41 (1): 2-8.

Occludin dephosphorylation in early development of Xenopus laevis., Cordenonsi M, Mazzon E, De Rigo L, Baraldo S, Meggio F, Citi S., J Cell Sci. December 1, 1997; 110 ( Pt 24) 3131-9.                

Biological activity of p27kip1 and its amino- and carboxy-terminal domains in G2/M transition of Xenopus oocytes., Font de Mora J, Uren A, Heidaran M, Santos E., Oncogene. November 20, 1997; 15 (21): 2541-51.

Phentolamine block of KATP channels is mediated by Kir6.2., Proks P, Ashcroft FM., Proc Natl Acad Sci U S A. October 14, 1997; 94 (21): 11716-20.

Expression cloning of a rat hypothalamic galanin receptor coupled to phosphoinositide turnover., Smith KE, Forray C, Walker MW, Jones KA, Tamm JA, Bard J, Branchek TA, Linemeyer DL, Gerald C., J Biol Chem. September 26, 1997; 272 (39): 24612-6.

A member of the Ste20/PAK family of protein kinases is involved in both arrest of Xenopus oocytes at G2/prophase of the first meiotic cell cycle and in prevention of apoptosis., Faure S, Vigneron S, Dorée M, Morin N., EMBO J. September 15, 1997; 16 (18): 5550-61.

Regulation of quantal secretion by neurotrophic factors at developing motoneurons in Xenopus cell cultures., Liou JC, Yang RS, Fu WM., J Physiol. August 15, 1997; 503 ( Pt 1) 129-39.

Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits., Trapp S, Tucker SJ, Ashcroft FM., Proc Natl Acad Sci U S A. August 5, 1997; 94 (16): 8872-7.

Characterization of the intracellular signalling pathways that underlie growth-factor-stimulated glucose transport in Xenopus oocytes: evidence for ras- and rho-dependent pathways of phosphatidylinositol 3-kinase activation., Thomson FJ, Jess TJ, Moyes C, Plevin R, Gould GW., Biochem J. August 1, 1997; 325 ( Pt 3) 637-43.

Inhibition of oncogenic and activated wild-type ras-p21 protein-induced oocyte maturation by peptides from the ras-binding domain of the raf-p74 protein, identified from molecular dynamics calculations., Chung D, Amar S, Glozman A, Chen JM, Friedman FK, Robinson R, Monaco R, Brandt-Rauf P, Yamaizumi Z, Pincus MR., J Protein Chem. August 1, 1997; 16 (6): 631-5.

Comparative effects of insulin on the activation of the Raf/Mos-dependent MAP kinase cascade in vitellogenic versus postvitellogenic Xenopus oocytes., Chesnel F, Bonnec G, Tardivel A, Boujard D., Dev Biol. August 1, 1997; 188 (1): 122-33.

The Xenopus proglucagon gene encodes novel GLP-1-like peptides with insulinotropic properties., Irwin DM, Satkunarajah M, Wen Y, Brubaker PL, Pederson RA, Wheeler MB., Proc Natl Acad Sci U S A. July 22, 1997; 94 (15): 7915-20.

Hormonal control of the in vitro uptake of [35S]sulfate by cartilage of Xenopus laevis tadpoles., Schneider A, Hanke W., Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. July 1, 1997; 117 (3): 317-22.

Functional characterization of the transactivation properties of the PDX-1 homeodomain protein., Peshavaria M, Henderson E, Sharma A, Wright CV, Stein R., Mol Cell Biol. July 1, 1997; 17 (7): 3987-96.

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor., Tucker SJ, Gribble FM, Zhao C, Trapp S, Ashcroft FM., Nature. May 8, 1997; 387 (6629): 179-83.

Characterization of the human and rat phospholemman (PLM) cDNAs and localization of the human PLM gene to chromosome 19q13.1., Chen LS, Lo CF, Numann R, Cuddy M., Genomics. May 1, 1997; 41 (3): 435-43.

SIP/SHIP inhibits Xenopus oocyte maturation induced by insulin and phosphatidylinositol 3-kinase., Deuter-Reinhard M, Apell G, Pot D, Klippel A, Williams LT, Kavanaugh WM., Mol Cell Biol. May 1, 1997; 17 (5): 2559-65.

Insulin effects on ouabain binding in A6 renal cells., Smet PD, Erlij D, Van Driessche W., Pflugers Arch. May 1, 1997; 434 (1): 11-8.

Interaction of MAD2 with the carboxyl terminus of the insulin receptor but not with the IGFIR. Evidence for release from the insulin receptor after activation., O'Neill TJ, Zhu Y, Gustafson TA., J Biol Chem. April 11, 1997; 272 (15): 10035-40.

The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide., Gribble FM, Tucker SJ, Ashcroft FM., EMBO J. March 17, 1997; 16 (6): 1145-52.

Novel effect of insulin: insulin-stimulated Na+ transport is mediated by hydrolysis of phosphoinositides., Isales C, Macala LJ, Rodriguez-Commes J, Gasalla-Herraiz J, Hayslett JP., Biochem Biophys Res Commun. February 3, 1997; 231 (1): 156-9.

Structure-activity relationships of cysteine-lacking pentapeptide derivatives that inhibit ras farnesyltransferase., Leonard DM, Shuler KR, Poulter CJ, Eaton SR, Sawyer TK, Hodges JC, Su TZ, Scholten JD, Gowan RC, Sebolt-Leopold JS, Doherty AM., J Med Chem. January 17, 1997; 40 (2): 192-200.

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5., Meijer L, Borgne A, Mulner O, Chong JP, Blow JJ, Inagaki N, Inagaki M, Delcros JG, Moulinoux JP., Eur J Biochem. January 15, 1997; 243 (1-2): 527-36.

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