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Summary Expression Phenotypes Gene Literature (677) GO Terms (3) Nucleotides (94) Proteins (51) Interactants (1024) Wiki
XB-GENEPAGE-485904

Papers associated with ins



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Elevated circulating levels of xenopsin-related peptide-1 are associated with polycystic ovary syndrome., Temur M, Özün Özbay P, Aksun S, Yilmaz Ö, Çift T, Üstünel S, Calan M., Arch Gynecol Obstet. October 1, 2017; 296 (4): 841-846.

Comparison of phenotypic and global gene expression changes in Xenopus tropicalis embryos induced by agonists of RAR and RXR., Zhu J, Hu L, Li L, Huang X, Shi H., Toxicol Appl Pharmacol. September 1, 2017; 330 40-47.

Actions of PGLa-AM1 and its [A14K] and [A20K] analogues and their therapeutic potential as anti-diabetic agents., Owolabi BO, Musale V, Ojo OO, Moffett RC, McGahon MK, Curtis TM, Conlon JM, Flatt PR, Abdel-Wahab YHA., Biochimie. July 1, 2017; 138 1-12.

Eukaryotic initiation factor eIF6 modulates the expression of Kermit 2/XGIPC in IGF- regulated eye development., De Marco N, Tussellino M, Carotenuto R, Ronca R, Rizzolio S, Biffo S, Campanella C., Dev Biol. July 1, 2017; 427 (1): 148-154.        

Insulin-like growth factor 1 regulation of proliferation and differentiation of Xenopus laevis myogenic cells in vitro., Miyata S, Yada T, Ishikawa N, Taheruzzaman K, Hara R, Matsuzaki T, Nishikawa A., In Vitro Cell Dev Biol Anim. March 1, 2017; 53 (3): 231-247.

Insulin and SGK1 reduce the function of Na+/monocarboxylate transporter 1 (SMCT1/SLC5A8)., López-Barradas A, González-Cid T, Vázquez N, Gavi-Maza M, Reyes-Camacho A, Velázquez-Villegas LA, Ramírez V, Zandi-Nejad K, Mount DB, Torres N, Tovar AR, Romero MF, Gamba G, Plata C., Am J Physiol Cell Physiol. November 1, 2016; 311 (5): C720-C734.

The histone methyltransferase Setd7 promotes pancreatic progenitor identity., Kofent J, Zhang J, Spagnoli FM., Development. October 1, 2016; 143 (19): 3573-3581.                        

The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity., Iordanov I, Mihályi C, Tóth B, Csanády L., Elife. July 6, 2016; 5                     

Neonatal diabetes caused by a homozygous KCNJ11 mutation demonstrates that tiny changes in ATP sensitivity markedly affect diabetes risk., Vedovato N, Cliff E, Proks P, Poovazhagi V, Flanagan SE, Ellard S, Hattersley AT, Ashcroft FM., Diabetologia. July 1, 2016; 59 (7): 1430-1436.        

Metabolic and immune impairments induced by the endocrine disruptors benzo[a]pyrene and triclosan in Xenopus tropicalis., Regnault C, Willison J, Veyrenc S, Airieau A, Méresse P, Fortier M, Fournier M, Brousseau P, Raveton M, Reynaud S., Chemosphere. July 1, 2016; 155 519-527.

Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes., Babiker T, Vedovato N, Patel K, Thomas N, Finn R, Männikkö R, Chakera AJ, Flanagan SE, Shepherd MH, Ellard S, Ashcroft FM, Hattersley AT., Diabetologia. June 1, 2016; 59 (6): 1162-6.    

Xenopus as a model system for studying pancreatic development and diabetes., Kofent J, Spagnoli FM., Semin Cell Dev Biol. March 1, 2016; 51 106-16.  

Electron Transport Chain Remodeling by GSK3 during Oogenesis Connects Nutrient State to Reproduction., Sieber MH, Thomsen MB, Spradling AC., Cell. January 28, 2016; 164 (3): 420-32.              

SGK3 Sensitivity of Voltage Gated K+ Channel Kv1.5 (KCNA5)., Ahmed M, Fezai M, Uzcategui NL, Hosseinzadeh Z, Lang F., Cell Physiol Biochem. January 1, 2016; 38 (1): 359-67.

Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients., Nakayama T, Fisher M, Fisher M, Nakajima K, Odeleye AO, Zimmerman KB, Fish MB, Yaoita Y, Chojnowski JL, Lauderdale JD, Netland PA, Grainger RM., Dev Biol. December 15, 2015; 408 (2): 328-44.                              

The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway., Luehders K, Sasai N, Davaapil H, Kurosawa-Yoshida M, Hiura H, Brah T, Ohnuma S., Development. October 1, 2015; 142 (19): 3351-61.                              

Understanding How the Subcommissural Organ and Other Periventricular Secretory Structures Contribute via the Cerebrospinal Fluid to Neurogenesis., Guerra MM, González C, Caprile T, Jara M, Vío K, Muñoz RI, Rodríguez S, Rodríguez EM., Front Cell Neurosci. September 23, 2015; 9 480.                

A novel role for Celf1 in vegetal RNA localization during Xenopus oogenesis., Bauermeister D, Claußen M, Pieler T., Dev Biol. September 15, 2015; 405 (2): 214-24.            

Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2'-phosphate., Tóth B, Iordanov I, Csanády L., J Gen Physiol. May 1, 2015; 145 (5): 419-30.              

Insulin-induced cell division is controlled by the adaptor Grb14 in a Chfr-dependent manner., Perdereau D, Cailliau K, Browaeys-Poly E, Lescuyer A, Carré N, Benhamed F, Goenaga D, Burnol AF., Cell Signal. April 1, 2015; 27 (4): 798-806.

Evaluation of developmental toxicity and teratogenicity of diclofenac using Xenopus embryos., Chae JP, Park MS, Hwang YS, Min BH, Kim SH, Lee HS, Park MJ., Chemosphere. February 1, 2015; 120 52-8.

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism., Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M., Sci Rep. January 12, 2015; 5 11603.                                  

Inhibitory effects of insulin on GABAA currents modulated by the GABAA alpha subunit., Williams DB., J Recept Signal Transduct Res. January 1, 2015; 35 (6): 516-22.

Magainin-AM2 improves glucose homeostasis and beta cell function in high-fat fed mice., Ojo OO, Srinivasan DK, Owolabi BO, Conlon JM, Flatt PR, Abdel-Wahab YH., Biochim Biophys Acta. January 1, 2015; 1850 (1): 80-7.

Determination of Alkali-Sensing Parts of the Insulin Receptor-Related Receptor Using the Bioinformatic Approach., Deyev IE, Popova NV, Petrenko AG., Acta Naturae. January 1, 2015; 7 (2): 80-6.      

Positive Surgical Margin, HPV Persistence, and Expression of Both TPX2 and PD-L1 Are Associated with Persistence/Recurrence of Cervical Intraepithelial Neoplasia after Cervical Conization., Zhang H, Zhang T, You Z, Zhang Y., PLoS One. January 1, 2015; 10 (12): e0142868.    

Genome-wide view of TGFβ/Foxh1 regulation of the early mesendoderm program., Chiu WT, Charney Le R, Blitz IL, Fish MB, Li Y, Biesinger J, Xie X, Cho KW., Development. December 1, 2014; 141 (23): 4537-47.                                  

Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating., Tóth B, Iordanov I, Csanády L., Proc Natl Acad Sci U S A. November 25, 2014; 111 (47): 16949-54.

Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic study., Proks P, de Wet H, Ashcroft FM., J Gen Physiol. November 1, 2014; 144 (5): 469-86.                  

Insulin is involved in transcriptional regulation of NKCC and the CFTR Cl(-) channel through PI3K activation and ERK inactivation in renal epithelial cells., Sun H, Niisato N, Inui T, Marunaka Y., J Physiol Sci. November 1, 2014; 64 (6): 433-43.

Recessive mutations in PCBD1 cause a new type of early-onset diabetes., Simaite D, Kofent J, Gong M, Rüschendorf F, Jia S, Arn P, Bentler K, Ellaway C, Kühnen P, Hoffmann GF, Blau N, Spagnoli FM, Hübner N, Raile K., Diabetes. October 1, 2014; 63 (10): 3557-64.

Inhibition of the intestinal sodium-coupled glucose transporter 1 (SGLT1) by extracts and polyphenols from apple reduces postprandial blood glucose levels in mice and humans., Schulze C, Bangert A, Kottra G, Geillinger KE, Schwanck B, Vollert H, Blaschek W, Daniel H., Mol Nutr Food Res. September 1, 2014; 58 (9): 1795-808.

A Novel Long-Acting Glucagon-Like Peptide-1 Agonist with Improved Efficacy in Insulin Secretion and β-Cell Growth., Kim HY, Hwang JI, Moon MJ, Seong JY., Endocrinol Metab (Seoul). September 1, 2014; 29 (3): 320-7.        

MHC class I limits hippocampal synapse density by inhibiting neuronal insulin receptor signaling., Dixon-Salazar TJ, Fourgeaud L, Tyler CM, Poole JR, Park JJ, Boulanger LM., J Neurosci. August 27, 2014; 34 (35): 11844-56.

Impaired liver function in Xenopus tropicalis exposed to benzo[a]pyrene: transcriptomic and metabolic evidence., Regnault C, Worms IA, Oger-Desfeux C, MelodeLima C, Veyrenc S, Bayle ML, Combourieu B, Bonin A, Renaud J, Raveton M, Reynaud S., BMC Genomics. August 8, 2014; 15 666.          

Venus kinase receptors control reproduction in the platyhelminth parasite Schistosoma mansoni., Vanderstraete M, Gouignard N, Cailliau K, Morel M, Hahnel S, Leutner S, Beckmann S, Grevelding CG, Dissous C., PLoS Pathog. May 29, 2014; 10 (5): e1004138.              

Possible involvement of insulin-like growth factor 2 mRNA-binding protein 3 in zebrafish oocyte maturation as a novel cyclin B1 mRNA-binding protein that represses the translation in immature oocytes., Takahashi K, Kotani T, Katsu Y, Yamashita M., Biochem Biophys Res Commun. May 23, 2014; 448 (1): 22-7.

Insulin suppresses IKs (KCNQ1/KCNE1) currents, which require β-subunit KCNE1., Wu M, Obara Y, Norota I, Nagasawa Y, Ishii K., Pflugers Arch. May 1, 2014; 466 (5): 937-46.

MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney., Romaker D, Kumar V, Cerqueira DM, Cox RM, Wessely O., Proc Natl Acad Sci U S A. April 29, 2014; 111 (17): 6335-40.                                                          

IRE1α is essential for Xenopus pancreas development., Yuan L, Li X, Feng J, Yin C, Yuan F, Wang X., J Biomed Res. March 1, 2014; 28 (2): 123-31.              

The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength., de Lau W, Peng WC, Gros P, Clevers H., Genes Dev. February 15, 2014; 28 (4): 305-16.          

Upregulation of the Na⁺-coupled phosphate cotransporters NaPi-IIa and NaPi-IIb by B-RAF., Pakladok T, Hosseinzadeh Z, Lebedeva A, Alesutan I, Lang F., J Membr Biol. February 1, 2014; 247 (2): 137-45.

Magainin-related peptides stimulate insulin-release and improve glucose tolerance in high fat fed mice., Ojo OO, Srinivasan DK, Owolabi BO, Flatt PR, Abdel-Wahab YH., Protein Pept Lett. January 1, 2014; 22 (3): 256-63.

Characterization of the insulin-like growth factor binding protein family in Xenopus tropicalis., Haramoto Y, Oshima T, Takahashi S, Ito Y., Int J Dev Biol. January 1, 2014; 58 (9): 705-11.                                            

The paradox of the contrasting roles of chronic magnesium deficiency in metabolic disorders and field cancerization., Rubin H., Magnes Res. January 1, 2014; 27 (3): 94-102.

FGT-1 is the major glucose transporter in C. elegans and is central to aging pathways., Feng Y, Williams BG, Koumanov F, Wolstenholme AJ, Holman GD., Biochem J. December 1, 2013; 456 (2): 219-29.            

Mutations in SLC2A2 gene reveal hGLUT2 function in pancreatic β cell development., Michau A, Guillemain G, Grosfeld A, Vuillaumier-Barrot S, Grand T, Keck M, L'Hoste S, Chateau D, Serradas P, Teulon J, De Lonlay P, Scharfmann R, Brot-Laroche E, Leturque A, Le Gall M., J Biol Chem. October 25, 2013; 288 (43): 31080-92.

FGT-1 is a mammalian GLUT2-like facilitative glucose transporter in Caenorhabditis elegans whose malfunction induces fat accumulation in intestinal cells., Kitaoka S, Morielli AD, Zhao FQ., PLoS One. June 4, 2013; 8 (6): e68475.              

Dual targeting of insulin and venus kinase Receptors of Schistosoma mansoni for novel anti-schistosome therapy., Vanderstraete M, Gouignard N, Cailliau K, Morel M, Lancelot J, Bodart JF, Dissous C., PLoS Negl Trop Dis. May 16, 2013; 7 (5): e2226.                

Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification., Zhang T, Guo X, Chen Y., PLoS One. May 15, 2013; 8 (5): e65058.                  

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