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Summary Expression Phenotypes Gene Literature (138) GO Terms (13) Nucleotides (519) Proteins (62) Interactants (594) Wiki

Papers associated with sgk1

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Two adjacent phosphorylation sites in the C-terminus of the channel''s α-subunit have opposing effects on epithelial sodium channel (ENaC) activity., Diakov A, Nesterov V, Dahlmann A, Korbmacher C., Pflugers Arch. January 1, 2022; 474 (7): 681-697.

Activation of SGK1.1 Upregulates the M-current in the Presence of Epilepsy Mutations., Martin-Batista E, Manville RW, Rivero-Pérez B, Bartolomé-Martín D, Alvarez de la Rosa D, Abbott GW, Giraldez T., Front Mol Neurosci. November 26, 2021; 14 798261.

Virus-Host Interactions of Enteroviruses and Parvovirus B19 in Myocarditis., Ho HT, Peischard S, Strutz-Seebohm N, Seebohm G., Cell Physiol Biochem. November 18, 2021; 55 (6): 679-703.        

Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis., Wu HY, Zhou YM, Liao ZQ, Zhong JW, Liu YB, Zhao H, Liang CQ, Huang RJ, Park KS, Feng SS, Zheng L, Cai DQ, Qi XF., NPJ Regen Med. June 29, 2021; 6 (1): 36.                    

Nervous NDRGs: the N-myc downstream-regulated gene family in the central and peripheral nervous system., Schonkeren SL, Massen M, van der Horst R, Koch A, Vaes N, Melotte V., Neurogenetics. October 1, 2019; 20 (4): 173-186.      

Annexin II Light Chain p11 Interacts With ENaC to Increase Functional Activity at the Membrane., Cheung TT, Ismail NAS, Moir R, Arora N, McDonald FJ, Condliffe SB., Front Physiol. February 1, 2019; 10 7.                

The phosphorylation site T613 in the β-subunit of rat epithelial Na+ channel (ENaC) modulates channel inhibition by Nedd4-2., Krueger B, Yang L, Korbmacher C, Rauh R., Pflugers Arch. April 1, 2018; 470 (4): 649-660.

Regulation of Kv1.4 potassium channels by PKC and AMPK kinases., Andersen MN, Skibsbye L, Saljic A, Larsen MZ, Rasmussen HB, Jespersen T., Channels (Austin). January 1, 2018; 12 (1): 34-44.              

High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Michiue T, Yamamoto T, Yasuoka Y, Goto T, Ikeda T, Nagura K, Nakayama T, Taira M, Kinoshita T., Dev Biol. June 15, 2017; 426 (2): 270-290.                  

Stress-Kinase Regulation of TASK-1 and TASK-3., Rinné S, Kiper AK, Schmidt C, Ortiz-Bonnin B, Zwiener S, Seebohm G, Decher N., Cell Physiol Biochem. January 1, 2017; 44 (3): 1024-1037.

Insulin and SGK1 reduce the function of Na+/monocarboxylate transporter 1 (SMCT1/SLC5A8)., López-Barradas A, González-Cid T, Vázquez N, Gavi-Maza M, Reyes-Camacho A, Velázquez-Villegas LA, Ramírez V, Zandi-Nejad K, Mount DB, Torres N, Tovar AR, Romero MF, Gamba G, Plata C., Am J Physiol Cell Physiol. November 1, 2016; 311 (5): C720-C734.

WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter., Lagnaz D, Arroyo JP, Chávez-Canales M, Vázquez N, Rizzo F, Spirlí A, Debonneville A, Staub O, Gamba G., Am J Physiol Renal Physiol. August 1, 2014; 307 (3): F275-86.

Serum and glucocorticoid-inducible kinase1 increases plasma membrane wt-CFTR in human airway epithelial cells by inhibiting its endocytic retrieval., Bomberger JM, Coutermarsh BA, Barnaby RL, Sato JD, Chapline MC, Stanton BA., PLoS One. February 21, 2014; 9 (2): e89599.                  

Up-regulation of Kir2.1 (KCNJ2) by the serum & glucocorticoid inducible SGK3., Munoz C, Pakladok T, Almilaji A, Elvira B, Decher N, Shumilina E, Lang F., Cell Physiol Biochem. January 1, 2014; 33 (2): 491-500.

WNK4 inhibits Ca(2+)-activated big-conductance potassium channels (BK) via mitogen-activated protein kinase-dependent pathway., Yue P, Zhang C, Lin DH, Sun P, Wang WH., Biochim Biophys Acta. October 1, 2013; 1833 (10): 2101-10.

The neuronal serum- and glucocorticoid-regulated kinase 1.1 reduces neuronal excitability and protects against seizures through upregulation of the M-current., Miranda P, Cadaveira-Mosquera A, González-Montelongo R, Villarroel A, González-Hernández T, Lamas JA, Alvarez de la Rosa D, Giraldez T., J Neurosci. February 6, 2013; 33 (6): 2684-96.

Disease-causing R1185C mutation of WNK4 disrupts a regulatory mechanism involving calmodulin binding and SGK1 phosphorylation sites., Na T, Wu G, Zhang W, Dong WJ, Peng JB., Am J Physiol Renal Physiol. January 1, 2013; 304 (1): F8-F18.

PIKfyve sensitivity of hERG channels., Pakladok T, Almilaji A, Munoz C, Alesutan I, Lang F., Cell Physiol Biochem. January 1, 2013; 31 (6): 785-94.

Identification of a novel signaling pathway and its relevance for GluA1 recycling., Seebohm G, Neumann S, Theiss C, Novkovic T, Hill EV, Tavaré JM, Lang F, Hollmann M, Manahan-Vaughan D, Strutz-Seebohm N., PLoS One. January 1, 2012; 7 (3): e33889.                

Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway., Arroyo JP, Lagnaz D, Ronzaud C, Vázquez N, Ko BS, Moddes L, Ruffieux-Daidié D, Hausel P, Koesters R, Yang B, Stokes JB, Hoover RS, Gamba G, Staub O., J Am Soc Nephrol. September 1, 2011; 22 (9): 1707-19.

PKB/SGK-resistant GSK3 enhances phosphaturia and calciuria., Föller M, Kempe DS, Boini KM, Pathare G, Siraskar B, Capuano P, Alesutan I, Sopjani M, Stange G, Mohebbi N, Bhandaru M, Ackermann TF, Judenhofer MS, Pichler BJ, Biber J, Wagner CA, Lang F., J Am Soc Nephrol. May 1, 2011; 22 (5): 873-80.

The kinase SGK1 in the endoderm and mesoderm promotes ectodermal survival by down-regulating components of the death-inducing signaling complex., Endo T, Kusakabe M, Sunadome K, Yamamoto T, Nishida E., Sci Signal. January 18, 2011; 4 (156): ra2.

Stimulation of Na+/K+ ATPase activity and Na+ coupled glucose transport by β-catenin., Sopjani M, Alesutan I, Wilmes J, Dërmaku-Sopjani M, Lam RS, Koutsouki E, Jakupi M, Föller M, Lang F., Biochem Biophys Res Commun. November 19, 2010; 402 (3): 467-70.

The neuronal-specific SGK1.1 kinase regulates {delta}-epithelial Na+ channel independently of PY motifs and couples it to phospholipase C signaling., Wesch D, Miranda P, Afonso-Oramas D, Althaus M, Castro-Hernández J, Dominguez J, Morty RE, Clauss W, González-Hernández T, Alvarez de la Rosa D, Giraldez T., Am J Physiol Cell Physiol. October 1, 2010; 299 (4): C779-90.

Stimulation of ENaC activity by rosiglitazone is PPARγ-dependent and correlates with SGK1 expression increase., Renauld S, Tremblay K, Ait-Benichou S, Simoneau-Roy M, Garneau H, Staub O, Chraïbi A., J Membr Biol. August 1, 2010; 236 (3): 259-70.

Phosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel., Hallows KR, Bhalla V, Oyster NM, Wijngaarden MA, Lee JK, Li H, Chandran S, Xia X, Huang Z, Chalkley RJ, Burlingame AL, Pearce D., J Biol Chem. July 9, 2010; 285 (28): 21671-8.

COMMD1 downregulates the epithelial sodium channel through Nedd4-2., Ke Y, Butt AG, Swart M, Liu YF, McDonald FJ., Am J Physiol Renal Physiol. June 1, 2010; 298 (6): F1445-56.

Regulation of the Ca(2+) channel TRPV6 by the kinases SGK1, PKB/Akt, and PIKfyve., Sopjani M, Kunert A, Czarkowski K, Klaus F, Laufer J, Föller M, Lang F., J Membr Biol. February 1, 2010; 233 (1-3): 35-41.

Regulation of the glutamate transporter EAAT4 by PIKfyve., Alesutan IS, Ureche ON, Laufer J, Klaus F, Zürn A, Lindner R, Strutz-Seebohm N, Tavaré JM, Boehmer C, Palmada M, Lang UE, Seebohm G, Lang F., Cell Physiol Biochem. January 1, 2010; 25 (2-3): 187-94.

The serum and glucocorticoid inducible kinases SGK1-3 stimulate the neutral amino acid transporter SLC6A19., Böhmer C, Sopjani M, Klaus F, Lindner R, Laufer J, Jeyaraj S, Lang F, Palmada M., Cell Physiol Biochem. January 1, 2010; 25 (6): 723-32.

60kDa lysophospholipase, a new Sgk1 molecular partner involved in the regulation of ENaC., Menniti M, Iuliano R, Föller M, Sopjani M, Alesutan I, Mariggiò S, Nofziger C, Perri AM, Amato R, Blazer-Yost B, Corda D, Lang F, Perrotti N., Cell Physiol Biochem. January 1, 2010; 26 (4-5): 587-96.

Protein kinase B alpha (PKBα) stimulates the epithelial sodium channel (ENaC) heterologously expressed in Xenopus laevis oocytes by two distinct mechanisms., Diakov A, Nesterov V, Mokrushina M, Rauh R, Korbmacher C., Cell Physiol Biochem. January 1, 2010; 26 (6): 913-24.

PIKfyve upregulates CFTR activity., Gehring EM, Lam RS, Siraskar G, Koutsouki E, Seebohm G, Ureche ON, Ureche L, Baltaev R, Tavare JM, Lang F., Biochem Biophys Res Commun. December 18, 2009; 390 (3): 952-7.

Stimulation of electrogenic intestinal dipeptide transport by the glucocorticoid dexamethasone., Rexhepaj R, Rotte A, Kempe DS, Sopjani M, Föller M, Gehring EM, Bhandaru M, Gruner I, Mack AF, Rubio-Aliaga I, Nässl AM, Daniel H, Kuhl D, Lang F., Pflugers Arch. November 1, 2009; 459 (1): 191-202.

Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway., Rozansky DJ, Cornwall T, Subramanya AR, Rogers S, Yang YF, David LL, Zhu X, Yang CL, Ellison DH., J Clin Invest. September 1, 2009; 119 (9): 2601-12.

Regulation of the Na(+)-coupled glutamate transporter EAAT3 by PIKfyve., Klaus F, Gehring EM, Zürn A, Laufer J, Lindner R, Strutz-Seebohm N, Tavaré JM, Rothstein JD, Boehmer C, Palmada M, Gruner I, Lang UE, Seebohm G, Lang F., Neurochem Int. May 1, 2009; 54 (5-6): 372-7.

PIKfyve-dependent regulation of the Cl- channel ClC-2., Klaus F, Laufer J, Czarkowski K, Strutz-Seebohm N, Seebohm G, Lang F., Biochem Biophys Res Commun. April 10, 2009; 381 (3): 407-11.

Functional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2., Edinger RS, Lebowitz J, Li H, Alzamora R, Wang H, Johnson JP, Hallows KR., J Biol Chem. January 2, 2009; 284 (1): 150-157.

The C-terminal PDZ-binding motif in the Kv1.5 potassium channel governs its modulation by the Na+/H+ exchanger regulatory factor 2., Laufer J, Boehmer C, Jeyaraj S, Knuwer M, Klaus F, Lindner R, Palmada M, Lang F., Cell Physiol Biochem. January 1, 2009; 23 (1-3): 25-36.

Regulation of the glutamate transporter EAAT2 by PIKfyve., Gehring EM, Zurn A, Klaus F, Laufer J, Sopjani M, Lindner R, Strutz-Seebohm N, Tavaré JM, Boehmer C, Palmada M, Lang UE, Seebohm G, Lang F., Cell Physiol Biochem. January 1, 2009; 24 (5-6): 361-8.

Cholesterol depletion of the plasma membrane prevents activation of the epithelial sodium channel (ENaC) by SGK1., Krueger B, Haerteis S, Yang L, Hartner A, Rauh R, Korbmacher C, Diakov A., Cell Physiol Biochem. January 1, 2009; 24 (5-6): 605-18.

Long QT syndrome-associated mutations in KCNQ1 and KCNE1 subunits disrupt normal endosomal recycling of IKs channels., Seebohm G, Strutz-Seebohm N, Ureche ON, Henrion U, Baltaev R, Mack AF, Korniychuk G, Steinke K, Tapken D, Pfeufer A, Kääb S, Bucci C, Attali B, Merot J, Tavare JM, Hoppe UC, Sanguinetti MC, Lang F., Circ Res. December 5, 2008; 103 (12): 1451-7.

Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1., Schuetz F, Kumar S, Poronnik P, Adams DJ., Am J Physiol Cell Physiol. July 1, 2008; 295 (1): C73-80.

Up-regulation of hypertonicity-activated myo-inositol transporter SMIT1 by the cell volume-sensitive protein kinase SGK1., Klaus F, Palmada M, Lindner R, Laufer J, Jeyaraj S, Lang F, Boehmer C., J Physiol. March 15, 2008; 586 (6): 1539-47.

Intracellular calcium plays a role as the second messenger of hypotonic stress in gene regulation of SGK1 and ENaC in renal epithelial A6 cells., Taruno A, Niisato N, Marunaka Y., Am J Physiol Renal Physiol. January 1, 2008; 294 (1): F177-86.

The role of SGK and CFTR in acute adaptation to seawater in Fundulus heteroclitus., Shaw JR, Sato JD, VanderHeide J, LaCasse T, Stanton CR, Lankowski A, Stanton SE, Chapline C, Coutermarsh B, Barnaby R, Karlson K, Stanton BA., Cell Physiol Biochem. January 1, 2008; 22 (1-4): 69-78.

The peptide transporter PEPT2 is targeted by the protein kinase SGK1 and the scaffold protein NHERF2., Boehmer C, Palmada M, Klaus F, Jeyaraj S, Lindner R, Laufer J, Daniel H, Lang F., Cell Physiol Biochem. January 1, 2008; 22 (5-6): 705-14.

Modulation of the voltage-gated potassium channel Kv1.5 by the SGK1 protein kinase involves inhibition of channel ubiquitination., Boehmer C, Laufer J, Jeyaraj S, Klaus F, Lindner R, Lang F, Palmada M., Cell Physiol Biochem. January 1, 2008; 22 (5-6): 591-600.

Regulation of the epithelial calcium channel TRPV6 by the serum and glucocorticoid-inducible kinase isoforms SGK1 and SGK3., Böhmer C, Palmada M, Kenngott C, Lindner R, Klaus F, Laufer J, Lang F., FEBS Lett. December 11, 2007; 581 (29): 5586-90.

(NDRG2) stimulates amiloride-sensitive Na+ currents in Xenopus laevis oocytes and fisher rat thyroid cells., Wielpütz MO, Lee IH, Dinudom A, Boulkroun S, Farman N, Cook DI, Korbmacher C, Rauh R., J Biol Chem. September 21, 2007; 282 (38): 28264-73.

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