Papers associated with rad50

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	Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts., Tatsukawa K, Sakamoto R, Kawasoe Y, Kubota Y, Tsurimoto T, Takahashi TS, Ohashi E., Nucleic Acids Res. April 12, 2024; 52 (6): 3146-3163.
	MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks., Montales K, Ruis K, Lindsay H, Michael WM., PLoS One. August 2, 2022; 17 (8): e0271905.
	Identification of SCN5a p.C335R Variant in a Large Family with Dilated Cardiomyopathy and Conduction Disease., Sedaghat-Hamedani F, Rebs S, El-Battrawy I, Chasan S, Krause T, Haas J, Zhong R, Liao Z, Xu Q, Zhou X, Akin I, Zitron E, Frey N, Streckfuss-Bömeke K, Kayvanpour E., Int J Mol Sci. November 30, 2021; 22 (23):
	Conservation and divergence of protein pathways in the vertebrate heart., Federspiel JD, Tandon P, Wilczewski CM, Wasson L, Herring LE, Venkatesh SS, Cristea IM, Conlon FL., PLoS Biol. September 6, 2019; 17 (9): e3000437.
	Mdc1 modulates the interaction between TopBP1 and the MRN complex during DNA damage checkpoint responses., Choi SH, Yoo HY., Biochem Biophys Res Commun. October 7, 2016; 479 (1): 5-11.
	MRN, CtIP, and BRCA1 mediate repair of topoisomerase II-DNA adducts., Aparicio T, Baer R, Gottesman M, Gautier J., J Cell Biol. February 15, 2016; 212 (4): 399-408.
	MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex., Lee KY, Im JS, Shibata E, Park J, Handa N, Kowalczykowski SC, Dutta A., Nat Commun. July 28, 2015; 6 7744.
	The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks., Lee J, Dunphy WG., Mol Biol Cell. May 1, 2013; 24 (9): 1343-53.
	A role for the MRN complex in ATR activation via TOPBP1 recruitment., Duursma AM, Driscoll R, Elias JE, Cimprich KA., Mol Cell. April 11, 2013; 50 (1): 116-22.
	The MRN-CtIP pathway is required for metaphase chromosome alignment., Rozier L, Guo Y, Peterson S, Sato M, Baer R, Gautier J, Mao Y., Mol Cell. March 28, 2013; 49 (6): 1097-107.
	Analysis of MRE11's function in the 5'-->3' processing of DNA double-strand breaks., Liao S, Guay C, Toczylowski T, Yan H., Nucleic Acids Res. May 1, 2012; 40 (10): 4496-506.
	Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts., Kumar S, Yoo HY, Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG., Cell Cycle. March 15, 2012; 11 (6): 1183-94.
	CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts., Ramírez-Lugo JS, Yoo HY, Yoon SJ, Dunphy WG., Cell Cycle. February 1, 2011; 10 (3): 469-80.
	The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis., Taylor EM, Cecillon SM, Bonis A, Chapman JR, Povirk LF, Lindsay HD., Nucleic Acids Res. January 1, 2010; 38 (2): 441-54.
	CtIP links DNA double-strand break sensing to resection., You Z, Shi LZ, Zhu Q, Wu P, Zhang YW, Basilio A, Tonnu N, Verma IM, Berns MW, Hunter T., Mol Cell. December 25, 2009; 36 (6): 954-69.
	PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin., Di Virgilio M, Ying CY, Gautier J., DNA Repair (Amst). November 2, 2009; 8 (11): 1311-20.
	The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM., Yoo HY, Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG., Mol Biol Cell. May 1, 2009; 20 (9): 2351-60.
	Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites., Xu C, Wu L, Cui G, Botuyan MV, Chen J, Mer G., J Mol Biol. August 29, 2008; 381 (2): 361-72.
	Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity., Jazayeri A, Balestrini A, Garner E, Haber JE, Costanzo V., EMBO J. July 23, 2008; 27 (14): 1953-62.
	A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex., Dupré A, Boyer-Chatenet L, Sattler RM, Modi AP, Lee JH, Nicolette ML, Kopelovich L, Jasin M, Baer R, Paull TT, Gautier J., Nat Chem Biol. February 1, 2008; 4 (2): 119-25.
	Telomere capping and cellular checkpoints: clues from fruit flies., Ciapponi L, Cenci G., Cytogenet Genome Res. January 1, 2008; 122 (3-4): 365-73.
	Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes., Bhaskara V, Dupré A, Lengsfeld B, Hopkins BB, Chan A, Lee JH, Zhang X, Gautier J, Zakian V, Paull TT., Mol Cell. March 9, 2007; 25 (5): 647-61.
	Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex., Dupré A, Boyer-Chatenet L, Gautier J., Nat Struct Mol Biol. May 1, 2006; 13 (5): 451-7.
	ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks., Trenz K, Smith E, Smith S, Costanzo V., EMBO J. April 19, 2006; 25 (8): 1764-74.
	Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11., Di Virgilio M, Gautier J., J Cell Biol. December 5, 2005; 171 (5): 765-71.
	ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1., You Z, Chahwan C, Bailis J, Hunter T, Russell P., Mol Cell Biol. July 1, 2005; 25 (13): 5363-79.
	Condensin and cohesin display different arm conformations with characteristic hinge angles., Anderson DE, Losada A, Erickson HP, Hirano T., J Cell Biol. February 4, 2002; 156 (3): 419-24.

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