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Summary Expression Phenotypes Gene Literature (61) GO Terms (9) Nucleotides (179) Proteins (43) Interactants (1207) Wiki
XB-GENEPAGE-480799

Papers associated with fzd8



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Polarized contact behavior in directionally migrating Xenopus gastrula mesendoderm., Nagel M, Winklbauer R., Int J Dev Biol. January 1, 2023; 67 (3): 79-90.              

Temporal transcriptomic profiling reveals dynamic changes in gene expression of Xenopus animal cap upon activin treatment., Satou-Kobayashi Y, Kim JD, Fukamizu A, Asashima M., Sci Rep. July 15, 2021; 11 (1): 14537.          

eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled., Wesslowski J, Kozielewicz P, Wang X, Cui H, Schihada H, Kranz D, Karuna M P, Levkin P, Gross JC, Boutros M, Schulte G, Davidson G., J Biol Chem. June 26, 2020; 295 (26): 8759-8774.          

Assembly of protein complexes restricts diffusion of Wnt3a proteins., Takada R, Mii Y, Krayukhina E, Maruyama Y, Mio K, Sasaki Y, Shinkawa T, Pack CG, Sako Y, Sato C, Uchiyama S, Takada S., Commun Biol. October 10, 2018; 1 165.              

Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus., Mii Y, Yamamoto T, Takada R, Mizumoto S, Matsuyama M, Yamada S, Takada S, Taira M., Nat Commun. December 7, 2017; 8 (1): 1973.                                                  

A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL, Medina-Ruiz S, Borday C, Bernard E, Vert JP, Eisen MB, Harland RM, Monsoro-Burq AH., PLoS Biol. October 19, 2017; 15 (10): e2004045.                                              

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.                                

Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula., Ding Y, Colozza G, Zhang K, Moriyama Y, Ploper D, Sosa EA, Benitez MDJ, De Robertis EM., Dev Biol. June 15, 2017; 426 (2): 176-187.                                  

Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis., Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.                        

Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs., Stevens ML, Chaturvedi P, Rankin SA, Rankin SA, Macdonald M, Jagannathan S, Yukawa M, Barski A, Zorn AM., Development. April 1, 2017; 144 (7): 1283-1295.                            

High-throughput analysis reveals novel maternal germline RNAs crucial for primordial germ cell preservation and proper migration., Owens DA, Butler AM, Aguero TH, Newman KM, Van Booven D, King ML., Development. January 15, 2017; 144 (2): 292-304.                                                                                        

Lens regeneration from the cornea requires suppression of Wnt/β-catenin signaling., Hamilton PW, Sun Y, Henry JJ., Exp Eye Res. April 1, 2016; 145 206-215.          

Noggin4 is a long-range inhibitor of Wnt8 signalling that regulates head development in Xenopus laevis., Eroshkin FM, Nesterenko AM, Borodulin AV, Martynova NY, Ermakova GV, Gyoeva FK, Orlov EE, Belogurov AA, Lukyanov KA, Bayramov AV, Zaraisky AG., Sci Rep. January 22, 2016; 6 23049.                                                            

Mechanotransduction During Vertebrate Neurulation., Sokol SY., Curr Top Dev Biol. January 1, 2016; 117 359-76.

GATA2 regulates Wnt signaling to promote primitive red blood cell fate., Mimoto MS, Kwon S, Green YS, Goldman D, Christian JL., Dev Biol. November 1, 2015; 407 (1): 1-11.                          

Control of vertebrate core planar cell polarity protein localization and dynamics by Prickle 2., Butler MT, Wallingford JB., Development. October 1, 2015; 142 (19): 3429-39.

Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan., Chang TH, Hsieh FL, Zebisch M, Harlos K, Elegheert J, Jones EY., Elife. July 9, 2015; 4                               

Sulf1 has ligand-dependent effects on canonical and non-canonical Wnt signalling., Fellgett SW, Maguire RJ, Pownall ME., J Cell Sci. April 1, 2015; 128 (7): 1408-21.                        

E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation., Wills AE, Baker JC., Dev Cell. February 9, 2015; 32 (3): 345-57.                  

Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism., Haramoto Y, Takahashi S, Oshima T, Onuma Y, Ito Y, Asashima M., Sci Rep. January 12, 2015; 5 11603.                                  

Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification., Yasuoka Y, Suzuki Y, Takahashi S, Someya H, Sudou N, Haramoto Y, Cho KW, Asashima M, Sugano S, Taira M., Nat Commun. July 9, 2014; 5 4322.        

The Wnt/JNK signaling target gene alcam is required for embryonic kidney development., Cizelsky W, Tata A, Kühl M, Kühl SJ., Development. May 1, 2014; 141 (10): 2064-74.          

Left-right patterning in Xenopus conjoined twin embryos requires serotonin signaling and gap junctions., Vandenberg LN, Blackiston DJ, Rea AC, Dore TM, Levin M., Int J Dev Biol. January 1, 2014; 58 (10-12): 799-809.                

Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling., Nedelcu D, Liu J, Xu Y, Xu Y, Jao C, Salic A., Nat Chem Biol. September 1, 2013; 9 (9): 557-64.          

Lypd6 enhances Wnt/β-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains., Özhan G, Sezgin E, Wehner D, Pfister AS, Kühl SJ, Kagermeier-Schenk B, Kühl M, Schwille P, Weidinger G., Dev Cell. August 26, 2013; 26 (4): 331-45.

Wnt11b is involved in cilia-mediated symmetry breakage during Xenopus left-right development., Walentek P, Schneider I, Schweickert A, Blum M., PLoS One. January 1, 2013; 8 (9): e73646.              

Structural basis of Wnt recognition by Frizzled., Janda CY, Waghray D, Levin AM, Thomas C, Garcia KC., Science. July 6, 2012; 337 (6090): 59-64.

Expression of Wnt signaling components during Xenopus pronephros development., Zhang B, Tran U, Wessely O., PLoS One. January 1, 2011; 6 (10): e26533.                      

Inversin relays Frizzled-8 signals to promote proximal pronephros development., Lienkamp S, Ganner A, Boehlke C, Schmidt T, Arnold SJ, Schäfer T, Romaker D, Schuler J, Hoff S, Powelske C, Eifler A, Krönig C, Bullerkotte A, Nitschke R, Kuehn EW, Kim E, Burkhardt H, Brox T, Ronneberger O, Gloy J, Walz G., Proc Natl Acad Sci U S A. November 23, 2010; 107 (47): 20388-93.                          

Centrosomal localization of Diversin and its relevance to Wnt signaling., Itoh K, Jenny A, Mlodzik M, Sokol SY., J Cell Sci. October 15, 2009; 122 (Pt 20): 3791-8.                

In vitro organogenesis from undifferentiated cells in Xenopus., Asashima M, Ito Y, Chan T, Michiue T, Nakanishi M, Suzuki K, Hitachi K, Okabayashi K, Kondow A, Ariizumi T., Dev Dyn. June 1, 2009; 238 (6): 1309-20.                      

The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling., Luyten A, Mortier E, Van Campenhout C, Taelman V, Degeest G, Wuytens G, Lambaerts K, David G, Bellefroid EJ, Zimmermann P., Mol Biol Cell. April 1, 2008; 19 (4): 1594-604.                  

Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings., Furushima K, Yamamoto A, Nagano T, Shibata M, Miyachi H, Abe T, Ohshima N, Kiyonari H, Aizawa S., Dev Biol. June 15, 2007; 306 (2): 480-92.  

Mutational analysis of Norrin-Frizzled4 recognition., Smallwood PM, Williams J, Xu Q, Leahy DJ, Nathans J., J Biol Chem. February 9, 2007; 282 (6): 4057-68.

Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos., Nagano T, Takehara S, Takahashi M, Aizawa S, Yamamoto A., Development. December 1, 2006; 133 (23): 4643-54.                  

Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., Rana AA, Collart C, Gilchrist MJ, Smith JC., PLoS Genet. November 17, 2006; 2 (11): e193.                                    

Metastasis-associated kinase modulates Wnt signaling to regulate brain patterning and morphogenesis., Kibardin A, Ossipova O, Sokol SY., Development. August 1, 2006; 133 (15): 2845-54.                    

Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling., Swain RK, Katoh M, Medina A, Steinbeisser H., Cell Commun Signal. October 19, 2005; 3 12.          

Novel Daple-like protein positively regulates both the Wnt/beta-catenin pathway and the Wnt/JNK pathway in Xenopus., Kobayashi H, Michiue T, Yukita A, Danno H, Sakurai K, Fukui A, Kikuchi A, Asashima M., Mech Dev. October 1, 2005; 122 (10): 1138-53.                      

Frodo proteins: modulators of Wnt signaling in vertebrate development., Brott BK, Sokol SY., Differentiation. September 1, 2005; 73 (7): 323-9.      

Reorganization of actin cytoskeleton by FRIED, a Frizzled-8 associated protein tyrosine phosphatase., Itoh K, Lisovsky M, Hikasa H, Sokol SY., Dev Dyn. September 1, 2005; 234 (1): 90-101.              

Comparative genomics on Dkk1 orthologs., Katoh Y, Katoh M., Int J Oncol. July 1, 2005; 27 (1): 275-9.

Vertebrate gastrulation: polarity genes control the matrix., Wallingford JB., Curr Biol. June 7, 2005; 15 (11): R414-6.    

Comparative genomics on Fzd8 orthologs., Katoh Y, Katoh M., Oncol Rep. May 1, 2005; 13 (5): 993-7.

Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF., Yamamoto A, Nagano T, Takehara S, Hibi M, Aizawa S., Cell. January 28, 2005; 120 (2): 223-35.                      

Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling., Itoh K, Brott BK, Bae GU, Ratcliffe MJ, Sokol SY., J Biol. January 1, 2005; 4 (1): 3.                  

The role of Xenopus frizzled-8 in pronephric development., Satow R, Chan TC, Asashima M., Biochem Biophys Res Commun. August 20, 2004; 321 (2): 487-94.          

Frodo interacts with Dishevelled to transduce Wnt signals., Gloy J, Hikasa H, Sokol SY., Nat Cell Biol. May 1, 2002; 4 (5): 351-7.

Frizzled-10, up-regulated in primary colorectal cancer, is a positive regulator of the WNT - beta-catenin - TCF signaling pathway., Terasaki H, Saitoh T, Shiokawa K, Katoh M., Int J Mol Med. February 1, 2002; 9 (2): 107-12.

Frizzled receptors activate a novel JNK-dependent pathway that may lead to apoptosis., Lisovsky M, Itoh K, Sokol SY., Curr Biol. January 8, 2002; 12 (1): 53-8.

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