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Summary Expression Phenotypes Gene Literature (666) GO Terms (3) Nucleotides (94) Proteins (50) Interactants (964) Wiki

Papers associated with ins

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25 paper(s) referencing morpholinos

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An amphibian high fat diet model confirms that endocrine disruptors can induce a metabolic syndrome in wild green frogs (Pelophylax spp. complex)., Veyrenc S, Regnault C, Sroda S, Raveton M, Reynaud S., Environ Pollut. October 15, 2022; 311 120009.

Insulin Receptor-Related Receptor Regulates the Rate of Early Development in Xenopus laevis., Korotkova DD, Gantsova EA, Goryashchenko AS, Eroshkin FM, Serova OV, Sokolov AS, Sharko F, Zhenilo SV, Martynova NY, Petrenko AG, Zaraisky AG, Deyev IE., Int J Mol Sci. August 17, 2022; 23 (16):                     

Discovery of once-weekly, peptide-based selective GLP-1 and cholecystokinin 2 receptors co-agonizts., Zhou F, Song P, Tang X, Yang Q, Zhou S, Xu R, Fang T, Jia Z, Han J., Peptides. July 1, 2022; 153 170811.

Discovery of a genetic module essential for assigning left-right asymmetry in humans and ancestral vertebrates., Szenker-Ravi E, Ott T, Khatoo M, Moreau de Bellaing A, Goh WX, Chong YL, Beckers A, Kannesan D, Louvel G, Anujan P, Ravi V, Bonnard C, Moutton S, Schoen P, Fradin M, Colin E, Megarbane A, Daou L, Chehab G, Di Filippo S, Rooryck C, Deleuze JF, Boland A, Arribard N, Eker R, Tohari S, Ng AY, Rio M, Lim CT, Eisenhaber B, Eisenhaber F, Venkatesh B, Amiel J, Crollius HR, Gordon CT, Gossler A, Roy S, Attie-Bitach T, Blum M, Bouvagnet P, Reversade B., Nat Genet. January 1, 2022; 54 (1): 62-72.

Stapled, Long-Acting Xenopus GLP-1-Based Dual GLP-1/Glucagon Receptor Agonists with Potent Therapeutic Efficacy for Metabolic Disease., Han C, Sun Y, Yang Q, Zhou F, Chen X, Wu L, Sun L, Han J., Mol Pharm. August 2, 2021; 18 (8): 2906-2923.

Genetic and Physiological Effects of Insulin on Human Urate Homeostasis., Mandal AK, Leask MP, Estiverne C, Choi HK, Merriman TR, Mount DB., Front Physiol. August 2, 2021; 12 713710.              

Functional rice with tandemly repeated Cbl-b ubiquitin ligase inhibitory pentapeptide prevents denervation-induced muscle atrophy in vivo., Akama K, Shimajiri Y, Kainou K, Iwasaki R, Nakao R, Nikawa T, Nishikawa A., Biosci Biotechnol Biochem. May 25, 2021; 85 (6): 1415-1421.

Beneficial actions of the [A14K] analog of the frog skin peptide PGLa-AM1 in mice with obesity and degenerative diabetes: A mechanistic study., Musale V, Moffett RC, Conlon JM, Flatt PR, Abdel-Wahab YH., Peptides. February 1, 2021; 136 170472.

Transgenerational metabolic disorders and reproduction defects induced by benzo[a]pyrene in Xenopus tropicalis., Usal M, Veyrenc S, Darracq-Ghitalla-Ciock M, Regnault C, Sroda S, Fini JB, Canlet C, Tremblay-Franco M, Raveton M, Reynaud S., Environ Pollut. January 15, 2021; 269 116109.

X-box-binding protein 1 is required for pancreatic development in Xenopus laevis., Yang J, Liu X, Yuan F, Liu J, Li D, Wei L, Wang X, Yuan L., Acta Biochim Biophys Sin (Shanghai). December 11, 2020; 52 (11): 1215-1226.

Inhibition of the facilitative sugar transporters (GLUTs) by tea extracts and catechins., Ni D, Ai Z, Munoz-Sandoval D, Suresh R, Ellis PR, Yuqiong C, Sharp PA, Butterworth PJ, Yu Z, Corpe CP., FASEB J. August 1, 2020; 34 (8): 9995-10010.

Phosphorylation of mouse intestinal basolateral amino acid uniporter LAT4 is controlled by food-entrained diurnal rhythm and dietary proteins., Oparija-Rogenmozere L, Rajendran A, Poncet N, Camargo SMR, Verrey F., PLoS One. May 29, 2020; 15 (5): e0233863.                          

Interactive Actions of Aldosterone and Insulin on Epithelial Na+ Channel Trafficking., Marunaka R, Marunaka Y., Int J Mol Sci. May 12, 2020; 21 (10):         

Selective profiling of N- and C-terminal nucleotide-binding sites in a TRPM2 channel., Tóth B, Iordanov I, Csanády L., J Gen Physiol. May 4, 2020; 152 (5):

Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors., Leippe P, Broichhagen J, Cailliau K, Mougel A, Morel M, Dissous C, Trauner D, Vicogne J., Angew Chem Int Ed Engl. April 20, 2020; 59 (17): 6720-6723.

Biochemical responses revealed in an amphibian species after exposure to a forgotten contaminant: An integrated biomarker assessment., Dahms-Verster S, Nel A, van Vuren JHJ, Greenfield R., Environ Toxicol Pharmacol. January 1, 2020; 73 103272.

Identification of Transient Receptor Potential Channel 4-Associated Protein as a Novel Candidate Gene Causing Congenital Primary Hypothyroidism., Choukair D, Eberle B, Vick P, Hermanns P, Weiss B, Paramasivam N, Schlesner M, Lornsen K, Roeth R, Klutmann C, Kreis J, Hoffmann GF, Pohlenz J, Rappold GA, Bettendorf M., Horm Res Paediatr. January 1, 2020; 93 (1): 16-29.

Concomitant exposure to benzo[a]pyrene and triclosan at environmentally relevant concentrations induces metabolic syndrome with multigenerational consequences in Silurana (Xenopus) tropicalis., Usal M, Regnault C, Veyrenc S, Couturier K, Batandier C, Bulteau AL, Lejon D, Combourieu B, Lafond T, Raveton M, Reynaud S., Sci Total Environ. November 1, 2019; 689 149-159.

Nutrient restriction causes reversible G2 arrest in Xenopus neural progenitors., McKeown CR, Cline HT., Development. October 24, 2019; 146 (20):             

Phosphoinositides modulate the voltage dependence of two-pore channel 3., Shimomura T, Kubo Y., J Gen Physiol. August 5, 2019; 151 (8): 986-1006.                              

Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates., Iordanov I, Tóth B, Szollosi A, Csanády L., Elife. April 2, 2019; 8                     

Ketone body modulation of ligand-gated ion channels., Pflanz NC, Daszkowski AW, James KA, Mihic SJ., Neuropharmacology. April 1, 2019; 148 21-30.

Liver Specification in the Absence of Cardiac Differentiation Revealed by Differential Sensitivity to Wnt/β Catenin Pathway Activation., Haworth K, Samuel L, Black S, Kirilenko P, Latinkic B., Front Physiol. February 1, 2019; 10 155.              

Identification of retinal homeobox (rax) gene-dependent genes by a microarray approach: The DNA endoglycosylase neil3 is a major downstream component of the rax genetic pathway., Pan Y, Kelly LE, El-Hodiri HM., Dev Dyn. November 1, 2018; 247 (11): 1199-1210.                            

A novel high-affinity inhibitor against the human ATP-sensitive Kir6.2 channel., Ramu Y, Xu Y, Xu Y, Lu Z., J Gen Physiol. July 2, 2018; 150 (7): 969-976.              

Permanent neonatal diabetes: combining sulfonylureas with insulin may be an effective treatment., Misra S, Vedovato N, Cliff E, De Franco E, Hattersley AT, Ashcroft FM, Oliver NS., Diabet Med. June 13, 2018;

Retinoic acid-induced expression of Hnf1b and Fzd4 is required for pancreas development in Xenopus laevis., Gere-Becker MB, Pommerenke C, Lingner T, Pieler T., Development. June 8, 2018; 145 (12):                                   

Binding of sulphonylureas to plasma proteins - A KATP channel perspective., Proks P, Kramer H, Haythorne E, Ashcroft FM., PLoS One. May 15, 2018; 13 (5): e0197634.        

Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation., Zhang Z, Tóth B, Szollosi A, Chen J, Csanády L., Elife. May 10, 2018; 7                         

Unexpected metabolic disorders induced by endocrine disruptors in Xenopus tropicalis provide new lead for understanding amphibian decline., Regnault C, Usal M, Veyrenc S, Couturier K, Batandier C, Bulteau AL, Lejon D, Sapin A, Combourieu B, Chetiveaux M, Le May C, Lafond T, Raveton M, Reynaud S., Proc Natl Acad Sci U S A. May 8, 2018; 115 (19): E4416-E4425.        

A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals., Zhang Y, Qin C, Yang L, Lu R, Zhao X, Nie G., BMC Genomics. April 11, 2018; 19 (1): 246.          

Xenopus-derived glucagon-like peptide-1 and polyethylene-glycosylated glucagon-like peptide-1 receptor agonists: long-acting hypoglycaemic and insulinotropic activities with potential therapeutic utilities., Han J, Fei Y, Zhou F, Chen X, Zhang Y, Liu L, Fu J., Br J Pharmacol. February 1, 2018; 175 (3): 544-557.

Isolation and Primary Culture Methods of Adult and Larval Myogenic Cells from Xenopus laevis., Taheruzzaman K, Nishikawa A., Methods Mol Biol. January 1, 2018; 1865 283-299.

Action of Protein Tyrosine Kinase Inhibitors on the Hypotonicity-Stimulated Trafficking Kinetics of Epithelial Na+ Channels (ENaC) in Renal Epithelial Cells: Analysis Using a Mathematical Model., Marunaka R, Taruno A, Yamamoto T, Kanamura N, Marunaka Y., Cell Physiol Biochem. January 1, 2018; 50 (1): 363-377.

Regulation of the insulin-Akt signaling pathway and glycolysis during dehydration stress in the African clawed frog Xenopus laevis., Wu CW, Tessier SN, Storey KB., Biochem Cell Biol. December 1, 2017; 95 (6): 663-671.

Differential cytolocation and functional assays of the two major human SLC30A8 (ZnT8) isoforms., Carvalho S, Molina-López J, Parsons D, Corpe C, Maret W, Hogstrand C., J Trace Elem Med Biol. December 1, 2017; 44 116-124.

Insulin treatment augments KCNQ1/KCNE1 currents but not KCNQ1 currents, which is associated with an increase in KCNE1 expression., Wu M, Obara Y, Ohshima S, Nagasawa Y, Ishii K., Biochem Biophys Res Commun. November 4, 2017; 493 (1): 409-415.

Apple and blackcurrant polyphenol-rich drinks decrease postprandial glucose, insulin and incretin response to a high-carbohydrate meal in healthy men and women., Castro-Acosta ML, Stone SG, Mok JE, Mhajan RK, Fu CI, Lenihan-Geels GN, Corpe CP, Hall WL., J Nutr Biochem. November 1, 2017; 49 53-62.

Elevated circulating levels of xenopsin-related peptide-1 are associated with polycystic ovary syndrome., Temur M, Özün Özbay P, Aksun S, Yilmaz Ö, Çift T, Üstünel S, Calan M., Arch Gynecol Obstet. October 1, 2017; 296 (4): 841-846.

Comparison of phenotypic and global gene expression changes in Xenopus tropicalis embryos induced by agonists of RAR and RXR., Zhu J, Hu L, Li L, Huang X, Shi H., Toxicol Appl Pharmacol. September 1, 2017; 330 40-47.

Actions of PGLa-AM1 and its [A14K] and [A20K] analogues and their therapeutic potential as anti-diabetic agents., Owolabi BO, Musale V, Ojo OO, Moffett RC, McGahon MK, Curtis TM, Conlon JM, Flatt PR, Abdel-Wahab YHA., Biochimie. July 1, 2017; 138 1-12.

Eukaryotic initiation factor eIF6 modulates the expression of Kermit 2/XGIPC in IGF- regulated eye development., De Marco N, Tussellino M, Carotenuto R, Ronca R, Rizzolio S, Biffo S, Campanella C., Dev Biol. July 1, 2017; 427 (1): 148-154.        

Insulin-like growth factor 1 regulation of proliferation and differentiation of Xenopus laevis myogenic cells in vitro., Miyata S, Yada T, Ishikawa N, Taheruzzaman K, Hara R, Matsuzaki T, Nishikawa A., In Vitro Cell Dev Biol Anim. March 1, 2017; 53 (3): 231-247.

Insulin and SGK1 reduce the function of Na+/monocarboxylate transporter 1 (SMCT1/SLC5A8)., López-Barradas A, González-Cid T, Vázquez N, Gavi-Maza M, Reyes-Camacho A, Velázquez-Villegas LA, Ramírez V, Zandi-Nejad K, Mount DB, Torres N, Tovar AR, Romero MF, Gamba G, Plata C., Am J Physiol Cell Physiol. November 1, 2016; 311 (5): C720-C734.

The histone methyltransferase Setd7 promotes pancreatic progenitor identity., Kofent J, Zhang J, Spagnoli FM., Development. October 1, 2016; 143 (19): 3573-3581.                        

The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity., Iordanov I, Mihályi C, Tóth B, Csanády L., Elife. July 6, 2016; 5                     

Neonatal diabetes caused by a homozygous KCNJ11 mutation demonstrates that tiny changes in ATP sensitivity markedly affect diabetes risk., Vedovato N, Cliff E, Proks P, Poovazhagi V, Flanagan SE, Ellard S, Hattersley AT, Ashcroft FM., Diabetologia. July 1, 2016; 59 (7): 1430-1436.        

Metabolic and immune impairments induced by the endocrine disruptors benzo[a]pyrene and triclosan in Xenopus tropicalis., Regnault C, Willison J, Veyrenc S, Airieau A, Méresse P, Fortier M, Fournier M, Brousseau P, Raveton M, Reynaud S., Chemosphere. July 1, 2016; 155 519-527.

Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes., Babiker T, Vedovato N, Patel K, Thomas N, Finn R, Männikkö R, Chakera AJ, Flanagan SE, Shepherd MH, Ellard S, Ashcroft FM, Hattersley AT., Diabetologia. June 1, 2016; 59 (6): 1162-6.    

Xenopus as a model system for studying pancreatic development and diabetes., Kofent J, Spagnoli FM., Semin Cell Dev Biol. March 1, 2016; 51 106-16.  

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