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Summary Expression Phenotypes Gene Literature (29) GO Terms (5) Nucleotides (151) Proteins (85) Interactants (67) Wiki
XB-GENEPAGE-494656

Papers associated with clcn2



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Leukoencephalopathy-causing CLCN2 mutations are associated with impaired Cl- channel function and trafficking., Gaitán-Peñas H, Apaja PM, Arnedo T, Castellanos A, Elorza-Vidal X, Soto D, Gasull X, Lukacs GL, Estévez R., J Physiol. November 15, 2017; 595 (22): 6993-7008.


Identification and characterization of the zebrafish ClC-2 chloride channel orthologs., Pérez-Rius C, Gaitán-Peñas H, Estévez R, Barrallo-Gimeno A., Pflugers Arch. August 1, 2015; 467 (8): 1769-81.


Downregulation of chloride channel ClC-2 by Janus kinase 3., Warsi J, Elvira B, Hosseinzadeh Z, Shumilina E, Lang F., J Membr Biol. May 1, 2014; 247 (5): 387-93.


Regulation of ClC-2 activity by SPAK and OSR1., Warsi J, Hosseinzadeh Z, Elvira B, Bissinger R, Shumilina E, Lang F., Kidney Blood Press Res. January 1, 2014; 39 (4): 378-87.


Characterization of an outward rectifying chloride current of Xenopus tropicalis oocytes., Ochoa-de la Paz LD, Espino-Saldaña AE, Arellano-Ostoa R, Reyes JP, Miledi R, Martinez-Torres A., Biochim Biophys Acta. August 1, 2013; 1828 (8): 1743-53.


De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy., Barcia G, Fleming MR, Deligniere A, Gazula VR, Brown MR, Langouet M, Chen H, Kronengold J, Abhyankar A, Cilio R, Nitschke P, Kaminska A, Boddaert N, Casanova JL, Desguerre I, Munnich A, Dulac O, Kaczmarek LK, Colleaux L, Nabbout R., Nat Genet. November 1, 2012; 44 (11): 1255-9.


Lubiprostone activates CFTR, but not ClC-2, via the prostaglandin receptor (EP(4))., Norimatsu Y, Moran AR, MacDonald KD., Biochem Biophys Res Commun. September 28, 2012; 426 (3): 374-9.


GlialCAM, a protein defective in a leukodystrophy, serves as a ClC-2 Cl(-) channel auxiliary subunit., Jeworutzki E, López-Hernández T, Capdevila-Nortes X, Sirisi S, Bengtsson L, Montolio M, Zifarelli G, Arnedo T, Müller CS, Schulte U, Nunes V, Martínez A, Jentsch TJ, Gasull X, Pusch M, Estévez R., Neuron. March 8, 2012; 73 (5): 951-61.                


Downregulation of ClC-2 by JAK2., Hosseinzadeh Z, Bhavsar SK, Lang F., Cell Physiol Biochem. January 1, 2012; 29 (5-6): 737-42.


A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels., Gradogna A, Babini E, Picollo A, Pusch M., J Gen Physiol. September 1, 2010; 136 (3): 311-23.              


Analysis of CLCN2 as candidate gene for megalencephalic leukoencephalopathy with subcortical cysts., Scheper GC, van Berkel CG, Leisle L, de Groot KE, Errami A, Jentsch TJ, Van der Knaap MS., Genet Test Mol Biomarkers. April 1, 2010; 14 (2): 255-7.


Isolation and characterization of a high affinity peptide inhibitor of ClC-2 chloride channels., Thompson CH, Olivetti PR, Fuller MD, Freeman CS, McMaster D, French RJ, Pohl J, Kubanek J, McCarty NA., J Biol Chem. September 18, 2009; 284 (38): 26051-62.


PIKfyve-dependent regulation of the Cl- channel ClC-2., Klaus F, Laufer J, Czarkowski K, Strutz-Seebohm N, Seebohm G, Lang F., Biochem Biophys Res Commun. April 10, 2009; 381 (3): 407-11.


Identification of ClC-2 and CIC-K2 chloride channels in cultured rat type IV spiral ligament fibrocytes., Qu C, Liang F, Smythe NM, Schulte BA., J Assoc Res Otolaryngol. June 1, 2007; 8 (2): 205-19.


Alterations in the cytoplasmic domain of CLCN2 result in altered gating kinetics., Paul J, Jeyaraj S, Huber SM, Seebohm G, Böhmer C, Lang F, Kremsner PG, Kun JF., Cell Physiol Biochem. January 1, 2007; 20 (5): 441-54.


Inhibition of ClC-2 chloride channels by a peptide component or components of scorpion venom., Thompson CH, Fields DM, Olivetti PR, Fuller MD, Zhang ZR, Kubanek J, McCarty NA., J Membr Biol. November 1, 2005; 208 (1): 65-76.


Serum and glucocorticoid inducible kinases functionally regulate ClC-2 channels., Palmada M, Dieter M, Boehmer C, Waldegger S, Lang F., Biochem Biophys Res Commun. September 3, 2004; 321 (4): 1001-6.


Gastric parietal cell secretory membrane contains PKA- and acid-activated Kir2.1 K+ channels., Malinowska DH, Sherry AM, Tewari KP, Cuppoletti J., Am J Physiol Cell Physiol. March 1, 2004; 286 (3): C495-506.


A common sequence variation of the CLCNKB gene strongly activates ClC-Kb chloride channel activity., Jeck N, Waldegger P, Doroszewicz J, Seyberth H, Waldegger S., Kidney Int. January 1, 2004; 65 (1): 190-7.


Phosphorylation and functional regulation of ClC-2 chloride channels expressed in Xenopus oocytes by M cyclin-dependent protein kinase., Furukawa T, Ogura T, Zheng YJ, Tsuchiya H, Nakaya H, Katayama Y, Inagaki N., J Physiol. May 1, 2002; 540 (Pt 3): 883-93.


Chloride channel activity of ClC-2 is modified by the actin cytoskeleton., Ahmed N, Ramjeesingh M, Wong S, Varga A, Garami E, Bear CE., Biochem J. December 15, 2000; 352 Pt 3 789-94.


Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives., Pusch M, Liantonio A, Bertorello L, Accardi A, De Luca A, Pierno S, Tortorella V, Camerino DC., Mol Pharmacol. September 1, 2000; 58 (3): 498-507.


Low expression of the ClC-2 chloride channel during postnatal development: a mechanism for the paradoxical depolarizing action of GABA and glycine in the hippocampus., Mladini M, Becchetti A, Didelon F, Bradbury A, Cherubini E., Proc Biol Sci. June 22, 1999; 266 (1425): 1207-13.


Chloride dependence of hyperpolarization-activated chloride channel gates., Pusch M, Jordt SE, Stein V, Jentsch TJ., J Physiol. March 1, 1999; 515 ( Pt 2) 341-53.


Comparison of voltage-activated Cl- channels in rat parotid acinar cells with ClC-2 in a mammalian expression system., Park K, Arreola J, Begenisich T, Melvin JE., J Membr Biol. May 15, 1998; 163 (2): 87-95.


Characteristics of rabbit ClC-2 current expressed in Xenopus oocytes and its contribution to volume regulation., Furukawa T, Ogura T, Katayama Y, Hiraoka M., Am J Physiol. February 1, 1998; 274 (2 Pt 1): C500-12.


Molecular dissection of gating in the ClC-2 chloride channel., Jordt SE, Jentsch TJ., EMBO J. April 1, 1997; 16 (7): 1582-92.


Inhibition of the inward-rectifying Cl- channel in rat choroid plexus by a decrease in extracellular pH., Kajita H, Brown PD., J Physiol. February 1, 1997; 498 ( Pt 3) 703-7.


Molecular cloning and characterization of a novel truncated from (ClC-2 beta) of ClC-2 alpha (ClC-2G) in rabbit heart., Furukawa T, Horikawa S, Terai T, Ogura T, Katayama Y, Hiraoka M., FEBS Lett. November 13, 1995; 375 (1-2): 56-62.

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