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Summary Expression Phenotypes Gene Literature (52) GO Terms (5) Nucleotides (87) Proteins (43) Interactants (176) Wiki
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Papers associated with kcnj10



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Heterooligomeric assembly of inward-rectifier K+ channels from subunits of different subfamilies: Kir2.1 (IRK1) and Kir4.1 (BIR10)., Fakler B, Bond CT, Adelman JP, Ruppersberg JP., Pflugers Arch. January 1, 1996; 433 (1-2): 77-83.

Cloning and characterization of two K+ inward rectifier (Kir) 1.1 potassium channel homologs from human kidney (Kir1.2 and Kir1.3)., Shuck ME, Piser TM, Bock JH, Slightom JL, Lee KS, Bienkowski MJ., J Biol Chem. January 3, 1997; 272 (1): 586-93.

Interaction of permeant and blocking ions in cloned inward-rectifier K+ channels., Oliver D, Hahn H, Antz C, Ruppersberg JP, Fakler B., Biophys J. May 1, 1998; 74 (5): 2318-26.

Cloning and characterization of a novel human inwardly rectifying potassium channel predominantly expressed in small intestine., Partiseti M, Collura V, Agnel M, Culouscou JM, Graham D., FEBS Lett. August 28, 1998; 434 (1-2): 171-6.

Partially active channels produced by PKA site mutation of the cloned renal K+ channel, ROMK2 (kir1.2)., MacGregor GG, Xu JZ, McNicholas CM, Giebisch G, Hebert SC., Am J Physiol. September 1, 1998; 275 (3): F415-22.

Expression of a functional Kir4 family inward rectifier K+ channel from a gene cloned from mouse liver., Pearson WL, Dourado M, Schreiber M, Salkoff L, Nichols CG., J Physiol. February 1, 1999; 514 ( Pt 3) (Pt 3): 639-53.

Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP., Tanabe K, Tucker SJ, Matsuo M, Proks P, Ashcroft FM, Seino S, Amachi T, Ueda K., J Biol Chem. February 12, 1999; 274 (7): 3931-3.

Opposite effects of pH on open-state probability and single channel conductance of kir4.1 channels., Yang Z, Jiang C., J Physiol. November 1, 1999; 520 Pt 3 921-7.

Modulation of kir4.1 and kir5.1 by hypercapnia and intracellular acidosis., Xu H, Cui N, Yang Z, Qu Z, Jiang C., J Physiol. May 1, 2000; 524 Pt 3 725-35.

Biophysical and molecular mechanisms underlying the modulation of heteromeric Kir4.1-Kir5.1 channels by CO2 and pH., Yang Z, Xu H, Cui N, Qu Z, Chanchevalap S, Shen W, Jiang C., J Gen Physiol. July 1, 2000; 116 (1): 33-45.                  

A single residue contributes to the difference between Kir4.1 and Kir1.1 channels in pH sensitivity, rectification and single channel conductance., Xu H, Yang Z, Cui N, Chanchevalap S, Valesky WW, Jiang C., J Physiol. October 15, 2000; 528 Pt 2 267-77.

Molecular determinants for the distinct pH sensitivity of Kir1.1 and Kir4.1 channels., Xu H, Yang Z, Cui N, Giwa LR, Abdulkadir L, Patel M, Sharma P, Shan G, Shen W, Jiang C., Am J Physiol Cell Physiol. November 1, 2000; 279 (5): C1464-71.

Interaction of stilbene disulphonates with cloned K(ATP) channels., Proks P, Jones P, Ashcroft FM., Br J Pharmacol. March 1, 2001; 132 (5): 973-82.

Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1., Pessia M, Imbrici P, D'Adamo MC, Salvatore L, Tucker SJ., J Physiol. April 15, 2001; 532 (Pt 2): 359-67.

Modulation of the heteromeric Kir4.1-Kir5.1 channels by P(CO(2)) at physiological levels., Cui N, Giwa LR, Xu H, Rojas A, Abdulkadir L, Jiang C., J Cell Physiol. November 1, 2001; 189 (2): 229-36.

Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning., Levin M, Thorlin T, Robinson KR, Nogi T, Mercola M., Cell. October 4, 2002; 111 (1): 77-89.              

Identification of domains that control the heteromeric assembly of Kir5.1/Kir4.0 potassium channels., Konstas AA, Korbmacher C, Tucker SJ., Am J Physiol Cell Physiol. April 1, 2003; 284 (4): C910-7.

Identification of a heteromeric interaction that influences the rectification, gating, and pH sensitivity of Kir4.1/Kir5.1 potassium channels., Casamassima M, D'Adamo MC, Pessia M, Tucker SJ., J Biol Chem. October 31, 2003; 278 (44): 43533-40.

Expression and coexpression of CO2-sensitive Kir channels in brainstem neurons of rats., Wu J, Xu H, Shen W, Jiang C., J Membr Biol. February 1, 2004; 197 (3): 179-91.

Gastric parietal cell secretory membrane contains PKA- and acid-activated Kir2.1 K+ channels., Malinowska DH, Sherry AM, Tewari KP, Cuppoletti J., Am J Physiol Cell Physiol. March 1, 2004; 286 (3): C495-506.

Functional consequences of polyamine synthesis inhibition by L-alpha-difluoromethylornithine (DFMO): cellular mechanisms for DFMO-mediated ototoxicity., Nie L, Feng W, Diaz R, Gratton MA, Doyle KJ, Yamoah EN., J Biol Chem. April 15, 2005; 280 (15): 15097-102.

Interaction of the Ca2+-sensing receptor with the inwardly rectifying potassium channels Kir4.1 and Kir4.2 results in inhibition of channel function., Huang C, Sindic A, Hill CE, Hujer KM, Chan KW, Sassen M, Wu Z, Kurachi Y, Nielsen S, Romero MF, Miller RT., Am J Physiol Renal Physiol. March 1, 2007; 292 (3): F1073-81.

H bonding at the helix-bundle crossing controls gating in Kir potassium channels., Rapedius M, Fowler PW, Shang L, Sansom MS, Tucker SJ, Baukrowitz T., Neuron. August 16, 2007; 55 (4): 602-14.                

Protein kinase C dependent inhibition of the heteromeric Kir4.1-Kir5.1 channel., Rojas A, Cui N, Su J, Yang L, Muhumuza JP, Jiang C., Biochim Biophys Acta. September 1, 2007; 1768 (9): 2030-42.

Modulation of the heteromeric Kir4.1-Kir5.1 channel by multiple neurotransmitters via Galphaq-coupled receptors., Rojas A, Su J, Yang L, Lee M, Cui N, Zhang X, Fountain D, Jiang C., J Cell Physiol. January 1, 2008; 214 (1): 84-95.

H,K-ATPase protein localization and Kir4.1 function reveal concordance of three axes during early determination of left-right asymmetry., Aw S, Adams DS, Qiu D, Levin M., Mech Dev. January 1, 2008; 125 (3-4): 353-72.    

Non-equivalent role of TM2 gating hinges in heteromeric Kir4.1/Kir5.1 potassium channels., Shang L, Tucker SJ., Eur Biophys J. February 1, 2008; 37 (2): 165-71.            

Mutations of KCNJ10 together with mutations of SLC26A4 cause digenic nonsyndromic hearing loss associated with enlarged vestibular aqueduct syndrome., Yang T, Gurrola JG, Wu H, Chiu SM, Wangemann P, Snyder PM, Smith RJ., Am J Hum Genet. May 1, 2009; 84 (5): 651-7.      

Epilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ10 mutations., Bockenhauer D, Feather S, Stanescu HC, Bandulik S, Zdebik AA, Reichold M, Tobin J, Lieberer E, Sterner C, Landoure G, Arora R, Sirimanna T, Thompson D, Cross JH, van't Hoff W, Al Masri O, Tullus K, Yeung S, Anikster Y, Klootwijk E, Hubank M, Dillon MJ, Heitzmann D, Arcos-Burgos M, Knepper MA, Dobbie A, Gahl WA, Warth R, Sheridan E, Kleta R., N Engl J Med. May 7, 2009; 360 (19): 1960-70.

Mutational and in silico analyses for antidepressant block of astroglial inward-rectifier Kir4.1 channel., Furutani K, Ohno Y, Inanobe A, Hibino H, Kurachi Y., Mol Pharmacol. June 1, 2009; 75 (6): 1287-95.

Modulation of Kir4.1 and Kir4.1-Kir5.1 channels by small changes in cell volume., Soe R, Macaulay N, Klaerke DA., Neurosci Lett. June 26, 2009; 457 (2): 80-4.

Modulation of Kir4.1 and Kir4.1-Kir5.1 channels by extracellular cations., Søe R, Andreasen M, Klaerke DA., Biochim Biophys Acta. September 1, 2009; 1788 (9): 1706-13.

Kir5.1 underlies long-lived subconductance levels in heteromeric Kir4.1/Kir5.1 channels from Xenopus tropicalis., Shang L, Ranson SV, Tucker SJ., Biochem Biophys Res Commun. October 23, 2009; 388 (3): 501-5.          

Comparative analysis of cholesterol sensitivity of Kir channels: role of the CD loop., Rosenhouse-Dantsker A, Leal-Pinto E, Logothetis DE, Levitan I., Channels (Austin). January 1, 2010; 4 (1): 63-6.

Molecular basis of decreased Kir4.1 function in SeSAME/EAST syndrome., Williams DM, Lopes CM, Rosenhouse-Dantsker A, Connelly HL, Matavel A, O-Uchi J, McBeath E, Gray DA., J Am Soc Nephrol. December 1, 2010; 21 (12): 2117-29.

Kir4.1 K+ channels are regulated by external cations., Edvinsson JM, Shah AJ, Palmer LG., Channels (Austin). January 1, 2011; 5 (3): 269-79.

KCNJ10 mutations disrupt function in patients with EAST syndrome., Freudenthal B, Kulaveerasingam D, Lingappa L, Shah MA, Brueton L, Wassmer E, Ognjanovic M, Dorison N, Reichold M, Bockenhauer D, Kleta R, Zdebik AA., Nephron Physiol. January 1, 2011; 119 (3): p40-8.

Resting potential, oncogene-induced tumorigenesis, and metastasis: the bioelectric basis of cancer in vivo., Lobikin M, Chernet B, Lobo D, Levin M., Phys Biol. December 1, 2012; 9 (6): 065002.

KCNJ10 mutations display differential sensitivity to heteromerisation with KCNJ16., Parrock S, Hussain S, Issler N, Differ AM, Lench N, Guarino S, Oosterveld MJ, Keijzer-Veen M, Brilstra E, van Wieringen H, Konijnenberg AY, Amin-Rasip S, Dumitriu S, Klootwijk E, Knoers N, Bockenhauer D, Kleta R, Zdebik AA., Nephron Physiol. January 1, 2013; 123 (3-4): 7-14.          

Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology., Na I, Redmon D, Kopa M, Qin Y, Xue B, Uversky VN., PLoS One. January 1, 2013; 8 (8): e73476.                      

Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model., Chernet BT, Levin M., Dis Model Mech. May 1, 2013; 6 (3): 595-607.                  

Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome., Mahmood F, Mozere M, Zdebik AA, Stanescu HC, Tobin J, Beales PL, Kleta R, Bockenhauer D, Russell C., Dis Model Mech. May 1, 2013; 6 (3): 652-60.        

Contributions of the Na⁺/K⁺-ATPase, NKCC1, and Kir4.1 to hippocampal K⁺ clearance and volume responses., Larsen BR, Assentoft M, Cotrina ML, Hua SZ, Nedergaard M, Kaila K, Voipio J, MacAulay N., Glia. April 1, 2014; 62 (4): 608-22.

A novel method for inducing nerve growth via modulation of host resting potential: gap junction-mediated and serotonergic signaling mechanisms., Blackiston DJ, Anderson GM, Rahman N, Bieck C, Levin M., Neurotherapeutics. January 1, 2015; 12 (1): 170-84.            

TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia., Jo AO, Ryskamp DA, Phuong TT, Verkman AS, Yarishkin O, MacAulay N, Križaj D., J Neurosci. September 30, 2015; 35 (39): 13525-37.                  

RNA-Seq and microarray analysis of the Xenopus inner ear transcriptome discloses orthologous OMIM(®) genes for hereditary disorders of hearing and balance., Ramírez-Gordillo D, Powers TR, van Velkinburgh JC, Trujillo-Provencio C, Schilkey F, Serrano EE., BMC Res Notes. November 18, 2015; 8 691.      

Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy., Sicca F, Ambrosini E, Marchese M, Sforna L, Servettini I, Valvo G, Brignone MS, Lanciotti A, Moro F, Grottesi A, Catacuzzeno L, Baldini S, Hasan S, D'Adamo MC, Franciolini F, Molinari P, Santorelli FM, Pessia M., Sci Rep. September 28, 2016; 6 34325.            

Lethal digenic mutations in the K+ channels Kir4.1 (KCNJ10) and SLACK (KCNT1) associated with severe-disabling seizures and neurodevelopmental delay., Hasan S, Balobaid A, Grottesi A, Dabbagh O, Cenciarini M, Rawashdeh R, Al-Sagheir A, Bove C, Macchioni L, Pessia M, Al-Owain M, D'Adamo MC., J Neurophysiol. October 1, 2017; 118 (4): 2402-2411.

Developmental gene expression patterns in the brain and liver of Xenopus tropicalis during metamorphosis climax., Yaoita Y, Nakajima K., Genes Cells. December 1, 2018; 23 (12): 998-1008.              

Identification of a unique endoplasmic retention motif in the Xenopus GIRK5 channel and its contribution to oocyte maturation., Rangel-Garcia CI, Salvador C, Chavez-Garcia K, Diaz-Bello B, Lopez-Gonzalez Z, Vazquez-Cruz L, Angel Vazquez-Martinez J, Ortiz-Navarrete V, Riveros-Rosas H, Escobar LI., FEBS Open Bio. April 1, 2021; 11 (4): 1093-1108.            

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