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Summary Expression Phenotypes Gene Literature (91) GO Terms (4) Nucleotides (85) Proteins (58) Interactants (104) Wiki
XB-GENEPAGE-5919505

Papers associated with kcnj5



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Heterologous multimeric assembly is essential for K+ channel activity of neuronal and cardiac G-protein-activated inward rectifiers., Duprat F, Lesage F, Guillemare E, Fink M, Hugnot JP, Bigay J, Lazdunski M, Romey G, Barhanin J., Biochem Biophys Res Commun. July 17, 1995; 212 (2): 657-63.

Pancreatic islet cells express a family of inwardly rectifying K+ channel subunits which interact to form G-protein-activated channels., Ferrer J, Nichols CG, Makhina EN, Salkoff L, Bernstein J, Gerhard D, Wasson J, Ramanadham S, Permutt A., J Biol Chem. November 3, 1995; 270 (44): 26086-91.

Time resolved kinetics of direct G beta 1 gamma 2 interactions with the carboxyl terminus of Kir3.4 inward rectifier K+ channel subunits., Doupnik CA, Dessauer CW, Slepak VZ, Gilman AG, Davidson N, Lester HA., Neuropharmacology. January 1, 1996; 35 (7): 923-31.

Localization and interaction of epitope-tagged GIRK1 and CIR inward rectifier K+ channel subunits., Kennedy ME, Nemec J, Clapham DE., Neuropharmacology. January 1, 1996; 35 (7): 831-9.

The K+ channel inward rectifier subunits form a channel similar to neuronal G protein-gated K+ channel., Velimirovic BM, Gordon EA, Lim NF, Navarro B, Clapham DE., FEBS Lett. January 22, 1996; 379 (1): 31-7.

A G-protein-activated inwardly rectifying K+ channel (GIRK4) from human hippocampus associates with other GIRK channels., Spauschus A, Lentes KU, Wischmeyer E, Dissmann E, Karschin C, Karschin A., J Neurosci. February 1, 1996; 16 (3): 930-8.

Coexpression with potassium channel subunits used to clone the Y2 receptor for neuropeptide Y., Rimland JM, Seward EP, Humbert Y, Ratti E, Trist DG, North RA., Mol Pharmacol. March 1, 1996; 49 (3): 387-90.

Specificity of coupling of muscarinic receptor isoforms to a novel chick inward-rectifying acetylcholine-sensitive K+ channel., Gadbut AP, Riccardi D, Wu L, Hebert SC, Galper JB., J Biol Chem. March 15, 1996; 271 (11): 6398-402.

Functional selectivity of orphanin FQ for its receptor coexpressed with potassium channel subunits in Xenopus laevis oocytes., Matthes H, Seward EP, Kieffer B, North RA., Mol Pharmacol. September 1, 1996; 50 (3): 447-50.

Metabotropic glutamate receptors activate G-protein-coupled inwardly rectifying potassium channels in Xenopus oocytes., Saugstad JA, Segerson TP, Westbrook GL., J Neurosci. October 1, 1996; 16 (19): 5979-85.

Identification of domains of the cardiac inward rectifying K+ channel, CIR, involved in the heteromultimer formation and in the G-protein gating., Kubo Y, Iizuka M., Biochem Biophys Res Commun. October 3, 1996; 227 (1): 240-7.

Na+ activation of the muscarinic K+ channel by a G-protein-independent mechanism., Sui JL, Chan KW, Logothetis DE., J Gen Physiol. November 1, 1996; 108 (5): 381-91.

Control of channel activity through a unique amino acid residue of a G protein-gated inwardly rectifying K+ channel subunit., Chan KW, Sui JL, Vivaudou M, Logothetis DE., Proc Natl Acad Sci U S A. November 26, 1996; 93 (24): 14193-8.

Subunit stoichiometry of a heteromultimeric G protein-coupled inward-rectifier K+ channel., Silverman SK, Lester HA, Dougherty DA., J Biol Chem. November 29, 1996; 271 (48): 30524-8.

A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation., Silverman SK, Kofuji P, Dougherty DA, Davidson N, Lester HA., Proc Natl Acad Sci U S A. December 24, 1996; 93 (26): 15429-34.

Subunit interactions in the assembly of neuronal Kir3.0 inwardly rectifying K+ channels., Döring F, Wischmeyer E, Spauschus A, Thomzig A, Veh R, Karschin A., Mol Cell Neurosci. January 1, 1997; 9 (3): 194-206.

ATP-dependent regulation of a G protein-coupled K+ channel (GIRK1/GIRK4) expressed in oocytes., Kim D, Watson M, Indyk V., Am J Physiol. January 1, 1997; 272 (1 Pt 2): H195-206.

Specific regions of heteromeric subunits involved in enhancement of G protein-gated K+ channel activity., Chan KW, Sui JL, Vivaudou M, Logothetis DE., J Biol Chem. March 7, 1997; 272 (10): 6548-55.

Activation of heteromeric G protein-gated inward rectifier K+ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons., Ehrengruber MU, Doupnik CA, Xu Y, Xu Y, Garvey J, Jasek MC, Lester HA, Davidson N., Proc Natl Acad Sci U S A. June 24, 1997; 94 (13): 7070-5.

Mu and delta opioid receptors are differentially desensitized by the coexpression of beta-adrenergic receptor kinase 2 and beta-arrestin 2 in xenopus oocytes., Kovoor A, Nappey V, Kieffer BL, Chavkin C., J Biol Chem. October 31, 1997; 272 (44): 27605-11.

A C-terminal peptide of the GIRK1 subunit directly blocks the G protein-activated K+ channel (GIRK) expressed in Xenopus oocytes., Luchian T, Dascal N, Dessauer C, Platzer D, Davidson N, Lester HA, Schreibmayer W., J Physiol. November 15, 1997; 505 ( Pt 1) 13-22.

Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants., Vivaudou M, Chan KW, Sui JL, Jan LY, Reuveny E, Logothetis DE., J Biol Chem. December 12, 1997; 272 (50): 31553-60.

Mechanosensitivity of the cardiac muscarinic potassium channel. A novel property conferred by Kir3.4 subunit., Ji S, John SA, Lu Y, Weiss JN., J Biol Chem. January 16, 1998; 273 (3): 1324-8.

Regulation of K+ and Ca++ channels by a family of neuropeptide Y receptors., Sun L, Philipson LH, Miller RJ., J Pharmacol Exp Ther. February 1, 1998; 284 (2): 625-32.

Asymmetrical contributions of subunit pore regions to ion selectivity in an inward rectifier K+ channel., Silverman SK, Lester HA, Dougherty DA., Biophys J. September 1, 1998; 75 (3): 1330-9.

Cloned human and rat galanin GALR3 receptors. Pharmacology and activation of G-protein inwardly rectifying K+ channels., Smith KE, Walker MW, Artymyshyn R, Bard J, Borowsky B, Tamm JA, Yao WJ, Vaysse PJ, Branchek TA, Gerald C, Jones KA., J Biol Chem. September 4, 1998; 273 (36): 23321-6.

Agonist induced homologous desensitization of mu-opioid receptors mediated by G protein-coupled receptor kinases is dependent on agonist efficacy., Kovoor A, Celver JP, Wu A, Chavkin C., Mol Pharmacol. October 1, 1998; 54 (4): 704-11.

Coupling of the expressed cannabinoid CB1 and CB2 receptors to phospholipase C and G protein-coupled inwardly rectifying K+ channels., Ho BY, Uezono Y, Takada S, Takase I, Izumi F., Recept Channels. January 1, 1999; 6 (5): 363-74.

Effect of extracellular cations on the inward rectifying K+ channels Kir2.1 and Kir3.1/Kir3.4., Owen JM, Quinn CC, Leach R, Findlay JB, Boyett MR., Exp Physiol. May 1, 1999; 84 (3): 471-88.

Functional expression and characterization of G-protein-gated inwardly rectifying K+ channels containing GIRK3., Jelacic TM, Sims SM, Clapham DE., J Membr Biol. May 15, 1999; 169 (2): 123-9.

Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization., Jin W, Brown S, Roche JP, Hsieh C, Celver JP, Kovoor A, Chavkin C, Mackie K., J Neurosci. May 15, 1999; 19 (10): 3773-80.

Bombesin receptors inhibit G protein-coupled inwardly rectifying K+ channels expressed in Xenopus oocytes through a protein kinase C-dependent pathway., Stevens EB, Shah BS, Pinnock RD, Lee K., Mol Pharmacol. June 1, 1999; 55 (6): 1020-7.

Activation of inwardly rectifying K+ channels by distinct PtdIns(4,5)P2 interactions., Zhang H, He C, Yan X, Mirshahi T, Logothetis DE., Nat Cell Biol. July 1, 1999; 1 (3): 183-8.

Agonist-dependent desensitization of the kappa opioid receptor by G protein receptor kinase and beta-arrestin., Appleyard SM, Celver J, Pineda V, Kovoor A, Wayman GA, Chavkin C., J Biol Chem. August 20, 1999; 274 (34): 23802-7.

Synergistic activation of G protein-gated inwardly rectifying potassium channels by the betagamma subunits of G proteins and Na(+) and Mg(2+) ions., Petit-Jacques J, Sui JL, Logothetis DE., J Gen Physiol. November 1, 1999; 114 (5): 673-84.                

Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a xenopus oocyte expression system., McAllister SD, Griffin G, Satin LS, Abood ME., J Pharmacol Exp Ther. November 1, 1999; 291 (2): 618-26.

Distinct specificities of inwardly rectifying K(+) channels for phosphoinositides., Rohács T, Chen J, Prestwich GD, Logothetis DE., J Biol Chem. December 17, 1999; 274 (51): 36065-72.

Inhibition by various antipsychotic drugs of the G-protein-activated inwardly rectifying K(+) (GIRK) channels expressed in xenopus oocytes., Kobayashi T, Ikeda K, Kumanishi T., Br J Pharmacol. April 1, 2000; 129 (8): 1716-22.

Slow modal gating of single G protein-activated K+ channels expressed in Xenopus oocytes., Yakubovich D, Pastushenko V, Bitler A, Dessauer CW, Dascal N., J Physiol. May 1, 2000; 524 Pt 3 737-55.

Heterologous facilitation of G protein-activated K(+) channels by beta-adrenergic stimulation via cAMP-dependent protein kinase., Müllner C, Vorobiov D, Bera AK, Uezono Y, Yakubovich D, Frohnwieser-Steinecker B, Dascal N, Schreibmayer W., J Gen Physiol. May 1, 2000; 115 (5): 547-58.              

TrkB activation by brain-derived neurotrophic factor inhibits the G protein-gated inward rectifier Kir3 by tyrosine phosphorylation of the channel., Rogalski SL, Appleyard SM, Pattillo A, Terman GW, Chavkin C., J Biol Chem. August 18, 2000; 275 (33): 25082-8.

Cs+ block of the cardiac muscarinic K+ channel, GIRK1/GIRK4, is not dependent on the aspartate residue at position 173., Dibb KM, Leach R, Lancaster MK, Findlay JB, Boyett MR., Pflugers Arch. September 1, 2000; 440 (5): 740-4.

G-protein mediated gating of inward-rectifier K+ channels., Mark MD, Herlitze S., Eur J Biochem. October 1, 2000; 267 (19): 5830-6.

Single channel studies of inward rectifier potassium channel regulation by muscarinic acetylcholine receptors., Bard J, Kunkel MT, Peralta EG., J Gen Physiol. November 1, 2000; 116 (5): 645-52.          

Residues and mechanisms for slow activation and Ba2+ block of the cardiac muscarinic K+ channel, Kir3.1/Kir3.4., Lancaster MK, Dibb KM, Quinn CC, Leach R, Lee JK, Lee JK, Findlay JB, Boyett MR., J Biol Chem. November 17, 2000; 275 (46): 35831-9.

Inhibition of a Gi-activated potassium channel (GIRK1/4) by the Gq-coupled m1 muscarinic acetylcholine receptor., Hill JJ, Peralta EG., J Biol Chem. February 23, 2001; 276 (8): 5505-10.

Identification of G protein-coupled, inward rectifier potassium channel gene products from the rat anterior pituitary gland., Gregerson KA, Flagg TP, O'Neill TJ, Anderson M, Lauring O, Horel JS, Welling PA., Endocrinology. July 1, 2001; 142 (7): 2820-32.

G protein-gated inwardly rectifying potassium channels are targets for volatile anesthetics., Weigl LG, Schreibmayer W., Mol Pharmacol. August 1, 2001; 60 (2): 282-9.

Gbeta residues that do not interact with Galpha underlie agonist-independent activity of K+ channels., Mirshahi T, Robillard L, Zhang H, Hébert TE, Logothetis DE., J Biol Chem. March 1, 2002; 277 (9): 7348-55.

Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus laevis oocytes., Choi S, Jung SY, Ko YS, Koh SR, Rhim H, Nah SY., Mol Pharmacol. April 1, 2002; 61 (4): 928-35.

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