Results 1 - 50 of 216 results
Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR. , Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK ., Nat Commun. November 5, 2022; 13 (1): 6681.
Maternal Wnt11b regulates cortical rotation during Xenopus axis formation: analysis of maternal-effect wnt11b mutants. , Houston DW , Elliott KL, Coppenrath K , Wlizla M , Horb ME ., Development. September 1, 2022; 149 (17):
ccr7 affects both morphogenesis and differentiation during early Xenopus embryogenesis. , Goto T , Michiue T , Shibuya H ., Dev Growth Differ. June 1, 2022; 64 (5): 254-260.
Lysosomes are required for early dorsal signaling in the Xenopus embryo. , Tejeda-Muñoz N, De Robertis EM ., Proc Natl Acad Sci U S A. April 26, 2022; 119 (17): e2201008119.
Rab7 is required for mesoderm patterning and gastrulation in Xenopus. , Kreis J, Wielath FM, Vick P ., Biol Open. July 15, 2021; 10 (7):
Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway. , Wang H, Wang C , Wang C , Wang C , Long Q, Zhang Y , Wang M, Liu J , Qi X, Cai D, Lu G, Sun J, Yao YG, Chan WY, Chan WY, Deng Y, Zhao H ., Development. May 15, 2021; 148 (10):
Geoffroea decorticans fruit extracts inhibit the wnt/β-catenin pathway, a therapeutic target in cancer. , Somaini GC, Aybar MJ , Vera NR, Tríbulo C., Biochem Biophys Res Commun. March 26, 2021; 546 118-123.
Hes5.9 Coordinate FGF and Notch Signaling to Modulate Gastrulation via Regulating Cell Fate Specification and Cell Migration in Xenopus tropicalis. , Huang X , Zhang L, Yang S, Zhang Y , Wu M, Chen P., Genes (Basel). November 18, 2020; 11 (11):
TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis. , Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG , He X ., Elife. September 14, 2020; 9
Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network. , Mukherjee S , Chaturvedi P , Rankin SA , Rankin SA , Fish MB, Wlizla M , Paraiso KD , MacDonald M, Chen X, Weirauch MT, Blitz IL , Cho KW , Zorn AM ., Elife. September 7, 2020; 9
Natural size variation among embryos leads to the corresponding scaling in gene expression. , Leibovich A, Edri T, Klein SL, Moody SA , Fainsod A ., Dev Biol. June 15, 2020; 462 (2): 165-179.
Chromatin accessibility and histone acetylation in the regulation of competence in early development. , Esmaeili M, Blythe SA , Tobias JW, Zhang K, Yang J , Klein PS ., Dev Biol. June 1, 2020; 462 (1): 20-35.
The secreted BMP antagonist ERFE is required for the development of a functional circulatory system in Xenopus. , Melchert J, Henningfeld KA , Richts S, Lingner T, Jonigk D, Pieler T ., Dev Biol. March 15, 2020; 459 (2): 138-148.
Pinhead signaling regulates mesoderm heterogeneity via FGF receptor-dependent pathway. , Ossipova O, Itoh K, Radu A, Ezan J, Sokol SY ., Development. January 1, 2020;
PTK7 proteolytic fragment proteins function during early Xenopus development. , Lichtig H, Cohen Y, Bin-Nun N, Golubkov V, Frank D ., Dev Biol. September 1, 2019; 453 (1): 48-55.
The Spatiotemporal Control of Zygotic Genome Activation. , Gentsch GE , Owens NDL, Smith JC ., iScience. June 28, 2019; 16 485-498.
Mechanical strain, novel genes and evolutionary insights: news from the frog left- right organizer. , Blum M , Ott T., Curr Opin Genet Dev. June 1, 2019; 56 8-14.
A dual function of FGF signaling in Xenopus left- right axis formation. , Schneider I, Kreis J, Schweickert A , Blum M , Vick P ., Development. May 10, 2019; 146 (9):
Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway. , Neitzel LR, Spencer ZT, Nayak A, Cselenyi CS, Benchabane H, Youngblood CQ, Zouaoui A, Ng V, Stephens L, Hann T, Patton JG, Robbins D, Ahmed Y, Lee E ., Mech Dev. April 1, 2019; 156 20-31.
Non-acylated Wnts Can Promote Signaling. , Speer KF, Sommer A, Tajer B, Mullins MC, Klein PS , Lemmon MA., Cell Rep. January 22, 2019; 26 (4): 875-883.e5.
WDR5 regulates left- right patterning via chromatin-dependent and -independent functions. , Kulkarni SS , Khokha MK ., Development. November 28, 2018; 145 (23):
Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates. , Yan L, Chen J , Zhu X, Sun J, Wu X, Shen W, Zhang W, Tao Q , Tao Q , Meng A., Science. November 23, 2018; 362 (6417):
Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis. , Ding Y , Colozza G , Sosa EA, Moriyama Y , Rundle S, Salwinski L, De Robertis EM ., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.
An Early Function of Polycystin-2 for Left- Right Organizer Induction in Xenopus. , Vick P , Kreis J, Schneider I, Tingler M, Getwan M , Thumberger T , Beyer T, Schweickert A , Blum M ., iScience. April 27, 2018; 2 76-85.
Head formation requires Dishevelled degradation that is mediated by March2 in concert with Dapper1. , Lee H , Lee H , Cheong SM, Han W, Koo Y, Jo SB, Cho GS, Yang JS , Kim S, Han JK ., Development. April 10, 2018; 145 (7):
Retinoic acid promotes stem cell differentiation and embryonic development by transcriptionally activating CFTR. , Li X, Fok KL, Guo J, Wang Y, Liu Z, Chen Z, Wang C , Ruan YC, Yu SS , Zhao H , Wu J , Jiang X, Chan HC., Biochim Biophys Acta Mol Cell Res. April 1, 2018; 1865 (4): 605-615.
Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left- Right Organizer in Xenopus. , Sempou E, Lakhani OA, Amalraj S, Khokha MK ., Front Physiol. February 5, 2018; 9 1705.
RAPGEF5 Regulates Nuclear Translocation of β-Catenin. , Griffin JN, Del Viso F, Duncan AR, Robson A, Hwang W, Kulkarni S , Liu KJ , Liu KJ , Khokha MK ., Dev Cell. January 22, 2018; 44 (2): 248-260.e4.
Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. , Kirsch N, Chang LS, Koch S, Glinka A , Dolde C, Colozza G , Benitez MDJ, De Robertis EM , Niehrs C ., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.
The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus. , Zhu X, Xing R, Tan R, Dai R, Tao Q , Tao Q ., Mech Dev. October 1, 2017; 147 28-36.
Both Nuclear Size and DNA Amount Contribute to Midblastula Transition Timing in Xenopus laevis. , Jevtić P, Levy DL ., Sci Rep. August 11, 2017; 7 (1): 7908.
Two-Element Transcriptional Regulation in the Canonical Wnt Pathway. , Kim K, Cho J, Hilzinger TS, Nunns H, Liu A, Ryba BE, Goentoro L ., Curr Biol. August 7, 2017; 27 (15): 2357-2364.e5.
Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula. , Ding Y , Colozza G , Zhang K, Moriyama Y , Ploper D, Sosa EA, Benitez MDJ, De Robertis EM ., Dev Biol. June 15, 2017; 426 (2): 176-187.
Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing. , Popov IK, Kwon T , Crossman DK, Crowley MR, Wallingford JB , Chang C ., Dev Biol. June 15, 2017; 426 (2): 429-441.
Genome organization of the vg1 and nodal3 gene clusters in the allotetraploid frog Xenopus laevis. , Suzuki A , Suzuki A , Uno Y , Takahashi S , Grimwood J, Schmutz J, Mawaribuchi S, Yoshida H, Takebayashi-Suzuki K, Ito M, Matsuda Y , Rokhsar D , Taira M ., Dev Biol. June 15, 2017; 426 (2): 236-244.
High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis. , Michiue T , Yamamoto T , Yasuoka Y, Goto T , Ikeda T, Nagura K, Nakayama T , Taira M , Kinoshita T ., Dev Biol. June 15, 2017; 426 (2): 270-290.
The phosphatase Pgam5 antagonizes Wnt/ β-Catenin signaling in embryonic anterior- posterior axis patterning. , Rauschenberger V, Bernkopf DB, Krenn S, Jalal K, Heller J, Behrens J, Gentzel M, Schambony A ., Development. June 15, 2017; 144 (12): 2234-2247.
Brg1 chromatin remodeling ATPase balances germ layer patterning by amplifying the transcriptional burst at midblastula transition. , Wagner G, Singhal N, Nicetto D, Straub T, Kremmer E, Rupp RAW ., PLoS Genet. May 12, 2017; 13 (5): e1006757.
Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis. , Ding Y , Ploper D, Sosa EA, Colozza G , Moriyama Y , Benitez MD, Zhang K, Merkurjev D, De Robertis EM ., Proc Natl Acad Sci U S A. April 11, 2017; 114 (15): E3081-E3090.
The MLL/ Setd1b methyltransferase is required for the Spemann''s organizer gene activation in Xenopus. , Lin H, Min Z, Tao Q , Tao Q ., Mech Dev. November 1, 2016; 142 1-9.
Cholesterol-rich membrane microdomains modulate Wnt/ β-catenin morphogen gradient during Xenopus development. , Reis AH, Moreno MM, Maia LA, Oliveira FP, Santos AS, Abreu JG ., Mech Dev. November 1, 2016; 142 30-39.
Genome evolution in the allotetraploid frog Xenopus laevis. , Session AM , Uno Y , Kwon T , Chapman JA, Toyoda A, Takahashi S , Fukui A , Hikosaka A , Suzuki A , Suzuki A , Kondo M, van Heeringen SJ, Quigley I , Heinz S, Ogino H , Ochi H , Hellsten U, Lyons JB, Simakov O, Putnam N, Stites J, Kuroki Y, Tanaka T, Michiue T , Watanabe M, Bogdanovic O , Lister R, Georgiou G, Paranjpe SS, van Kruijsbergen I, Shu S, Carlson J, Kinoshita T , Ohta Y, Mawaribuchi S, Jenkins J, Grimwood J, Schmutz J, Mitros T, Mozaffari SV, Suzuki Y, Haramoto Y , Yamamoto TS , Takagi C, Heald R , Miller K, Haudenschild C, Kitzman J , Nakayama T , Izutsu Y , Robert J , Robert J , Fortriede J , Burns K , Lotay V , Karimi K , Yasuoka Y, Dichmann DS , Flajnik MF , Houston DW , Shendure J, DuPasquier L , Vize PD , Zorn AM , Ito M, Marcotte EM , Wallingford JB , Ito Y , Asashima M , Ueno N , Matsuda Y , Veenstra GJ , Fujiyama A, Harland RM , Taira M , Rokhsar DS ., Nature. October 20, 2016; 538 (7625): 336-343.
Merlin inhibits Wnt/ β-catenin signaling by blocking LRP6 phosphorylation. , Kim M , Kim S, Lee SH , Kim W, Sohn MJ, Kim HS , Kim J , Jho EH ., Cell Death Differ. October 1, 2016; 23 (10): 1638-47.
Gtpbp2 is a positive regulator of Wnt signaling and maintains low levels of the Wnt negative regulator Axin. , Gillis WQ, Kirmizitas A, Iwasaki Y , Ki DH, Wyrick JM, Thomsen GH ., Cell Commun Signal. August 2, 2016; 14 (1): 15.
Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules. , Nakamura Y, de Paiva Alves E, Veenstra GJ , Hoppler S ., Development. June 1, 2016; 143 (11): 1914-25.
A gradient of maternal Bicaudal-C controls vertebrate embryogenesis via translational repression of mRNAs encoding cell fate regulators. , Park S, Blaser S, Marchal MA, Houston DW , Sheets MD ., Development. March 1, 2016; 143 (5): 864-71.
Measuring Absolute RNA Copy Numbers at High Temporal Resolution Reveals Transcriptome Kinetics in Development. , Owens ND, Blitz IL , Lane MA, Patrushev I , Overton JD, Gilchrist MJ , Cho KW , Khokha MK ., Cell Rep. January 26, 2016; 14 (3): 632-47.
Specification of anteroposterior axis by combinatorial signaling during Xenopus development. , Carron C, Shi DL ., Wiley Interdiscip Rev Dev Biol. January 1, 2016; 5 (2): 150-68.
A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators. , Freeman J, Smith D, Latinkic B , Ewan K, Samuel L, Zollo M , Marino N, Tyas L, Jones N, Dale TC., Mol Cancer. December 8, 2015; 14 206.
NF2/ Merlin is required for the axial pattern formation in the Xenopus laevis embryo. , Zhu X, Min Z, Tan R, Tao Q , Tao Q ., Mech Dev. November 1, 2015; 138 Pt 3 305-12.