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Summary Expression Phenotypes Gene Literature (80) GO Terms (4) Nucleotides (52) Proteins (29) Interactants (159) Wiki
XB-GENEPAGE-6037400

Papers associated with kcna5



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Heteromultimeric assembly of human potassium channels. Molecular basis of a transient outward current?, Po S, Roberds S, Snyders DJ, Tamkun MM, Bennett PB., Circ Res. June 1, 1993; 72 (6): 1326-36.


Cloning and characterization of a Kv1.5 delayed rectifier K+ channel from vascular and visceral smooth muscles., Overturf KE, Russell SN, Carl A, Vogalis F, Hart PJ, Hume JR, Sanders KM, Horowitz B., Am J Physiol. November 1, 1994; 267 (5 Pt 1): C1231-8.


A delayed rectifier potassium channel cloned from bovine adrenal medulla. Functional analysis after expression in Xenopus oocytes and in a neuroblastoma cell line., García-Guzmán M, Sala F, Criado M, Sala S., FEBS Lett. November 7, 1994; 354 (2): 173-6.


Mechanism of clofilium block of the human Kv1.5 delayed rectifier potassium channel., Malayev AA, Nelson DJ, Philipson LH., Mol Pharmacol. January 1, 1995; 47 (1): 198-205.


4-Aminopyridine block of the noninactivating cloned K+ channel Kv1.5 expressed in Xenopus oocytes., Yamane T, Furukawa T, Hiraoka M., Am J Physiol. August 1, 1995; 269 (2 Pt 2): H556-64.


The voltage-dependent K+ channel (Kv1.5) cloned from rabbit heart and facilitation of inactivation of the delayed rectifier current by the rat beta subunit., Sasaki Y, Ishii K, Nunoki K, Yamagishi T, Taira N., FEBS Lett. September 18, 1995; 372 (1): 20-4.


Suppression of two cloned smooth muscle-derived delayed rectifier potassium channels by cholinergic agonists and phorbol esters., Vogalis F, Ward M, Horowitz B., Mol Pharmacol. December 1, 1995; 48 (6): 1015-23.


A novel K+ channel beta-subunit (hKv beta 1.3) is produced via alternative mRNA splicing., England SK, Uebele VN, Kodali J, Bennett PB, Tamkun MM., J Biol Chem. December 1, 1995; 270 (48): 28531-4.


Susceptibility of cloned K+ channels to reactive oxygen species., Duprat F, Guillemare E, Romey G, Fink M, Lesage F, Lazdunski M, Honore E., Proc Natl Acad Sci U S A. December 5, 1995; 92 (25): 11796-800.


Functional characterization of Kv channel beta-subunits from rat brain., Heinemann SH, Rettig J, Graack HR, Pongs O., J Physiol. June 15, 1996; 493 ( Pt 3) 625-33.


HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine., Roy M, Dumaine R, Brown AM., Circulation. August 15, 1996; 94 (4): 817-23.


The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes., Suessbrich H, Schönherr R, Heinemann SH, Attali B, Lang F, Busch AE., Br J Pharmacol. March 1, 1997; 120 (5): 968-74.


Interactions of the nonsedating antihistamine loratadine with a Kv1.5-type potassium channel cloned from human heart., Lacerda AE, Roy ML, Lewis EW, Rampe D., Mol Pharmacol. August 1, 1997; 52 (2): 314-22.


Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241., Suessbrich H, Schönherr R, Heinemann SH, Lang F, Busch AE., FEBS Lett. September 8, 1997; 414 (2): 435-8.


Separable Kvbeta subunit domains alter expression and gating of potassium channels., Accili EA, Kiehn J, Yang Q, Wang Z, Brown AM, Wible BA., J Biol Chem. October 10, 1997; 272 (41): 25824-31.


A cellular model for long QT syndrome. Trapping of heteromultimeric complexes consisting of truncated Kv1.1 potassium channel polypeptides and native Kv1.4 and Kv1.5 channels in the endoplasmic reticulum., Folco E, Mathur R, Mori Y, Buckett P, Koren G., J Biol Chem. October 17, 1997; 272 (42): 26505-10.


Cloning and expression of a novel K+ channel regulatory protein, KChAP., Wible BA, Yang Q, Kuryshev YA, Accili EA, Brown AM., J Biol Chem. May 8, 1998; 273 (19): 11745-51.


Blockade of HERG and Kv1.5 by ketoconazole., Dumaine R, Roy ML, Brown AM., J Pharmacol Exp Ther. August 1, 1998; 286 (2): 727-35.


Differential sensitivity of voltage-gated potassium channels Kv1.5 and Kv1.2 to acidic pH and molecular identification of pH sensor., Steidl JV, Yool AJ., Mol Pharmacol. May 1, 1999; 55 (5): 812-20.


Protein kinase A phosphorylation alters Kvbeta1.3 subunit-mediated inactivation of the Kv1.5 potassium channel., Kwak YG, Hu N, Wei J, George AL, Grobaski TD, Tamkun MM, Murray KT., J Biol Chem. May 14, 1999; 274 (20): 13928-32.


[The expression of arrhythmic related genes on Xenopus oocytes for evaluation of class III antiarrhythmic drugs from ocean active material]., Xu DH, Xu SB., Yi Chuan Xue Bao. January 1, 2000; 27 (3): 195-201.


Hypomyelination and increased activity of voltage-gated K(+) channels in mice lacking protein tyrosine phosphatase epsilon., Peretz A, Gil-Henn H, Sobko A, Shinder V, Attali B, Elson A., EMBO J. August 1, 2000; 19 (15): 4036-45.


Molecular evidence for a role of Shaw (Kv3) potassium channel subunits in potassium currents of dog atrium., Yue L, Wang Z, Rindt H, Nattel S., J Physiol. September 15, 2000; 527 Pt 3 467-78.


Functional and molecular expression of a voltage-dependent K(+) channel (Kv1.1) in interstitial cells of Cajal., Hatton WJ, Mason HS, Carl A, Doherty P, Latten MJ, Kenyon JL, Sanders KM, Horowitz B., J Physiol. June 1, 2001; 533 (Pt 2): 315-27.


Cloning and expression of three K+ channel cDNAs from Xenopus muscle., Fry M, Paterno G, Moody-Corbett F., Brain Res Mol Brain Res. June 20, 2001; 90 (2): 135-48.          


Coupling of voltage-dependent potassium channel inactivation and oxidoreductase active site of Kvbeta subunits., Bähring R, Milligan CJ, Vardanyan V, Engeland B, Young BA, Dannenberg J, Waldschutz R, Edwards JP, Wray D, Pongs O., J Biol Chem. June 22, 2001; 276 (25): 22923-9.


Expression and function of native potassium channel [K(V)alpha1] subunits in terminal arterioles of rabbit., Cheong A, Dedman AM, Beech DJ., J Physiol. August 1, 2001; 534 (Pt 3): 691-700.


Characterization of a novel Kv1.5 channel blocker in Xenopus oocytes, CHO cells, human and rat cardiomyocytes., Bachmann A, Gutcher I, Kopp K, Brendel J, Bosch RF, Busch AE, Gögelein H., Naunyn Schmiedebergs Arch Pharmacol. November 1, 2001; 364 (5): 472-8.


Distinct mechanisms of block of Kv1.5 channels by tertiary and quaternary amine clofilium compounds., Steidl JV, Yool AJ., Biophys J. November 1, 2001; 81 (5): 2606-13.


SAP97 interacts with Kv1.5 in heterologous expression systems., Murata M, Buckett PD, Zhou J, Brunner M, Folco E, Koren G., Am J Physiol Heart Circ Physiol. December 1, 2001; 281 (6): H2575-84.


Modulation of Kv1.5 currents by protein kinase A, tyrosine kinase, and protein tyrosine phosphatase requires an intact cytoskeleton., Mason HS, Latten MJ, Godoy LD, Horowitz B, Kenyon JL., Mol Pharmacol. February 1, 2002; 61 (2): 285-93.


Identification, synthesis, and activity of novel blockers of the voltage-gated potassium channel Kv1.5., Peukert S, Brendel J, Pirard B, Brüggemann A, Below P, Kleemann HW, Hemmerle H, Schmidt W., J Med Chem. February 13, 2003; 46 (4): 486-98.


Molecular basis for Kv1.5 channel block: conservation of drug binding sites among voltage-gated K+ channels., Decher N, Pirard B, Bundis F, Peukert S, Baringhaus KH, Busch AE, Steinmeyer K, Sanguinetti MC., J Biol Chem. January 2, 2004; 279 (1): 394-400.


Effects of intracellular magnesium on Kv1.5 and Kv2.1 potassium channels., Tammaro P, Smirnov SV, Moran O., Eur Biophys J. February 1, 2005; 34 (1): 42-51.


A single residue in the S6 transmembrane domain governs the differential flecainide sensitivity of voltage-gated potassium channels., Herrera D, Mamarbachi A, Simoes M, Parent L, Sauvé R, Wang Z, Nattel S., Mol Pharmacol. August 1, 2005; 68 (2): 305-16.


Structural basis for competition between drug binding and Kvbeta 1.3 accessory subunit-induced N-type inactivation of Kv1.5 channels., Decher N, Kumar P, Gonzalez T, Renigunta V, Sanguinetti MC., Mol Pharmacol. October 1, 2005; 68 (4): 995-1005.


Analysis of voltage-gated potassium channel beta1 subunits in the porcine neonatal ductus arteriosus., Hayama E, Imamura S, Wu C, Nakazawa M, Matsuoka R, Nakanishi T., Pediatr Res. February 1, 2006; 59 (2): 167-74.


Novel, potent inhibitors of human Kv1.5 K+ channels and ultrarapidly activating delayed rectifier potassium current., Lagrutta A, Wang J, Fermini B, Salata JJ., J Pharmacol Exp Ther. June 1, 2006; 317 (3): 1054-63.


Binding site of a novel Kv1.5 blocker: a "foot in the door" against atrial fibrillation., Decher N, Kumar P, Gonzalez T, Pirard B, Sanguinetti MC., Mol Pharmacol. October 1, 2006; 70 (4): 1204-11.


The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae., Abdel-Mottaleb Y, Clynen E, Jalali A, Bosmans F, Vatanpour H, Schoofs L, Tytgat J., FEBS Lett. November 13, 2006; 580 (26): 6254-8.


Association of Kv1.5 and Kv1.3 contributes to the major voltage-dependent K+ channel in macrophages., Vicente R, Escalada A, Villalonga N, Texidó L, Roura-Ferrer M, Martín-Satué M, López-Iglesias C, Soler C, Solsona C, Tamkun MM, Felipe A., J Biol Chem. December 8, 2006; 281 (49): 37675-85.


Kvbeta1.3 reduces the degree of stereoselective bupivacaine block of Kv1.5 channels., Arias C, Guizy M, David M, Marzian S, González T, Decher N, Valenzuela C., Anesthesiology. October 1, 2007; 107 (4): 641-51.


Modulation of human Kv1.5 channel kinetics by N-cadherin., Koutsouki E, Lam RS, Seebohm G, Ureche ON, Ureche L, Baltaev R, Lang F., Biochem Biophys Res Commun. November 9, 2007; 363 (1): 18-23.


Modulation of the voltage-gated potassium channel Kv1.5 by the SGK1 protein kinase involves inhibition of channel ubiquitination., Boehmer C, Laufer J, Jeyaraj S, Klaus F, Lindner R, Lang F, Palmada M., Cell Physiol Biochem. January 1, 2008; 22 (5-6): 591-600.


Intrinsic electrostatic potential in the BK channel pore: role in determining single channel conductance and block., Carvacho I, Gonzalez W, Torres YP, Brauchi S, Alvarez O, Gonzalez-Nilo FD, Latorre R., J Gen Physiol. February 1, 2008; 131 (2): 147-61.                        


Voltage clamp fluorimetry reveals a novel outer pore instability in a mammalian voltage-gated potassium channel., Vaid M, Claydon TW, Rezazadeh S, Fedida D., J Gen Physiol. August 1, 2008; 132 (2): 209-22.                      


The C-terminal PDZ-binding motif in the Kv1.5 potassium channel governs its modulation by the Na+/H+ exchanger regulatory factor 2., Laufer J, Boehmer C, Jeyaraj S, Knuwer M, Klaus F, Lindner R, Palmada M, Lang F., Cell Physiol Biochem. January 1, 2009; 23 (1-3): 25-36.


Quercetin activates human Kv1.5 channels by a residue I502 in the S6 segment., Yang L, Ma JH, Zhang PH, Zou AR, Tu DN., Clin Exp Pharmacol Physiol. February 1, 2009; 36 (2): 154-61.


[Effects of telmisartan on voltage-gated Kv1.3 and Kv1.5 potassium channels expressed in Xenopus oocytes]., Li MW, Wang XP, Gao CY, Zou AR., Zhonghua Xin Xue Guan Bing Za Zhi. February 1, 2009; 37 (2): 165-8.


Effect of NIP-142 on potassium channel alpha-subunits Kv1.5, Kv4.2 and Kv4.3, and mouse atrial repolarization., Tanaka H, Namekata I, Hamaguchi S, Kawamura T, Masuda H, Tanaka Y, Iida-Tanaka N, Takahara A., Biol Pharm Bull. January 1, 2010; 33 (1): 138-41.

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