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Summary Expression Phenotypes Gene Literature (32) GO Terms (2) Nucleotides (33) Proteins (22) Interactants (45) Wiki
XB-GENEPAGE-6045054

Papers associated with kcne2



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The Amyloid Precursor Protein C99 Fragment Modulates Voltage-Gated Potassium Channels., Manville RW, Abbott GW., Cell Physiol Biochem. July 28, 2021; 55 (S3): 157-170.


β Subunits Control the Effects of Human Kv4.3 Potassium Channel Phosphorylation., Abbott GW., Front Physiol. January 1, 2017; 8 646.            


Molecular Cloning and Functional Expression of the Equine K+ Channel KV11.1 (Ether à Go-Go-Related/KCNH2 Gene) and the Regulatory Subunit KCNE2 from Equine Myocardium., Pedersen PJ, Thomsen KB, Olander ER, Hauser F, Tejada Mde L, Poulsen KL, Grubb S, Buhl R, Calloe K, Klaerke DA., PLoS One. September 4, 2015; 10 (9): e0138320.                  


Pacemaker activity of the human sinoatrial node: an update on the effects of mutations in HCN4 on the hyperpolarization-activated current., Verkerk AO, Wilders R., Int J Mol Sci. January 29, 2015; 16 (2): 3071-94.        


KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability., Abbott GW, Tai KK, Neverisky DL, Hansler A, Hu Z, Roepke TK, Lerner DJ, Chen Q, Liu L, Zupan B, Toth M, Haynes R, Huang X, Demirbas D, Buccafusca R, Gross SS, Kanda VA, Berry GT., Sci Signal. March 4, 2014; 7 (315): ra22.


Pacemaker activity of the human sinoatrial node: effects of HCN4 mutations on the hyperpolarization-activated current., Verkerk AO, Wilders R., Europace. March 1, 2014; 16 (3): 384-95.


Resting potential, oncogene-induced tumorigenesis, and metastasis: the bioelectric basis of cancer in vivo., Lobikin M, Chernet B, Lobo D, Levin M., Phys Biol. December 1, 2012; 9 (6): 065002.


Strong activation of ether-à-go-go-related gene 1 K+ channel isoforms by NS1643 in human embryonic kidney 293 and Chinese hamster ovary cells., Schuster AM, Glassmeier G, Bauer CK., Mol Pharmacol. November 1, 2011; 80 (5): 930-42.


Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state., Larsen AP, Steffensen AB, Grunnet M, Olesen SP., Biophys J. August 17, 2011; 101 (4): 818-27.


Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2., Lundby A, Jespersen T, Schmitt N, Grunnet M, Olesen SP, Cordeiro JM, Calloe K., Br J Pharmacol. August 1, 2010; 160 (8): 2028-44.


A shared mechanism for lipid- and beta-subunit-coordinated stabilization of the activated K+ channel voltage sensor., Choi E, Abbott GW., FASEB J. May 1, 2010; 24 (5): 1518-24.


Tanshinone IIA selectively enhances hyperpolarization-activated cyclic nucleotide-modulated (HCN) channel instantaneous current., Liang Q, Yang L, Wang Z, Huang S, Li S, Yang G., J Pharmacol Sci. July 1, 2009; 110 (3): 381-8.


Cardiac sodium channel gene variants and sudden cardiac death in women., Albert CM, Nam EG, Rimm EB, Jin HW, Hajjar RJ, Hunter DJ, MacRae CA, Ellinor PT., Circulation. January 1, 2008; 117 (1): 16-23.


Biophysical characterization of the short QT mutation hERG-N588K reveals a mixed gain-and loss-of-function., Grunnet M, Diness TG, Hansen RS, Olesen SP., Cell Physiol Biochem. January 1, 2008; 22 (5-6): 611-24.


KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval., Lundby A, Ravn LS, Svendsen JH, Olesen SP, Schmitt N., Heart Rhythm. December 1, 2007; 4 (12): 1532-41.


Probing the interaction between KCNE2 and KCNQ1 in their transmembrane regions., Liu XS, Zhang M, Jiang M, Wu DM, Tseng GN., J Membr Biol. April 1, 2007; 216 (2-3): 117-27.


The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes., Panaghie G, Abbott GW., J Gen Physiol. February 1, 2007; 129 (2): 121-33.                      


KCNE2 is colocalized with KCNQ1 and KCNE1 in cardiac myocytes and may function as a negative modulator of I(Ks) current amplitude in the heart., Wu DM, Jiang M, Zhang M, Liu XS, Korolkova YV, Tseng GN., Heart Rhythm. December 1, 2006; 3 (12): 1469-80.


Frequency-dependent modulation of KCNQ1 and HERG1 potassium channels., Diness TG, Hansen RS, Olesen SP, Grunnet M., Biochem Biophys Res Commun. May 19, 2006; 343 (4): 1224-33.


Effect of beta-adrenoceptor blockers on human ether-a-go-go-related gene (HERG) potassium channels., Dupuis DS, Klaerke DA, Olesen SP., Basic Clin Pharmacol Toxicol. February 1, 2005; 96 (2): 123-30.


Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome., Zehelein J, Thomas D, Khalil M, Wimmer AB, Koenen M, Licka M, Wu K, Kiehn J, Brockmeier K, Kreye VA, Karle CA, Katus HA, Ulmer HE, Schoels W., Biochim Biophys Acta. November 5, 2004; 1690 (3): 185-92.


Compound mutations: a common cause of severe long-QT syndrome., Westenskow P, Splawski I, Timothy KW, Keating MT, Sanguinetti MC., Circulation. April 20, 2004; 109 (15): 1834-41.


KCNE2 modulates current amplitudes and activation kinetics of HCN4: influence of KCNE family members on HCN4 currents., Decher N, Bundis F, Vajna R, Steinmeyer K., Pflugers Arch. September 1, 2003; 446 (6): 633-40.


RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies., Anantharam A, Lewis A, Panaghie G, Gordon E, McCrossan ZA, Lerner DJ, Abbott GW., J Biol Chem. April 4, 2003; 278 (14): 11739-45.


The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia., Scherer CR, Lerche C, Decher N, Dennis AT, Maier P, Ficker E, Busch AE, Wollnik B, Steinmeyer K., Br J Pharmacol. November 1, 2002; 137 (6): 892-900.


A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link?, Weerapura M, Nattel S, Chartier D, Caballero R, Hébert TE., J Physiol. April 1, 2002; 540 (Pt 1): 15-27.


Open channel block of HERG K(+) channels by vesnarinone., Kamiya K, Mitcheson JS, Yasui K, Kodama I, Sanguinetti MC., Mol Pharmacol. August 1, 2001; 60 (2): 244-53.


MinK-related peptide 1: A beta subunit for the HCN ion channel subunit family enhances expression and speeds activation., Yu H, Wu J, Potapova I, Wymore RT, Holmes B, Zuckerman J, Pan Z, Wang H, Shi W, Robinson RB, El-Maghrabi MR, Benjamin W, Dixon J, McKinnon D, Cohen IS, Wymore R., Circ Res. June 22, 2001; 88 (12): E84-7.


minK-related peptide 1 associates with Kv4.2 and modulates its gating function: potential role as beta subunit of cardiac transient outward channel?, Zhang M, Jiang M, Tseng GN., Circ Res. May 25, 2001; 88 (10): 1012-9.


KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel., Tinel N, Diochot S, Borsotto M, Lazdunski M, Barhanin J., EMBO J. December 1, 2000; 19 (23): 6326-30.


MinK subdomains that mediate modulation of and association with KvLQT1., Tapper AR, George AL., J Gen Physiol. September 1, 2000; 116 (3): 379-90.          


MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia., Abbott GW, Sesti F, Splawski I, Buck ME, Lehmann MH, Timothy KW, Keating MT, Goldstein SA., Cell. April 16, 1999; 97 (2): 175-87.

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