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Summary Expression Phenotypes Gene Literature (50) GO Terms (6) Nucleotides (207) Proteins (63) Interactants (166) Wiki
XB-GENEPAGE-951313

Papers associated with cdc7



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Novel role of DONSON in CMG helicase assembly during vertebrate DNA replication initiation., Hashimoto Y, Sadano K, Miyata N, Ito H, Tanaka H., EMBO J. September 4, 2023; 42 (17): e114131.                          

RTEL1 and MCM10 overcome topological stress during vertebrate replication termination., Campos LV, Van Ravenstein SX, Vontalge EJ, Greer BH, Heintzman DR, Kavlashvili T, McDonald WH, Rose KL, Eichman BF, Dewar JM., Cell Rep. February 28, 2023; 42 (2): 112109.                            

Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver., Rigolet M, Buisine N, Scharwatt M, Duvernois-Berthet E, Buchholz DR, Sachs LM., Int J Mol Sci. November 8, 2022; 23 (22):               

Polo-like kinase 1 (Plk1) regulates DNA replication origin firing and interacts with Rif1 in Xenopus., Ciardo D, Haccard O, Narassimprakash H, Cornu D, Guerrera IC, Goldar A, Marheineke K., Nucleic Acids Res. September 27, 2021; 49 (17): 9851-9869.                                        

Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination., Heintzman DR, Campos LV, Byl JAW, Osheroff N, Dewar JM., Cell Rep. October 8, 2019; 29 (2): 422-436.e5.                

Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements., Deng L, Wu RA, Sonneville R, Kochenova OV, Labib K, Pellman D, Walter JC., Mol Cell. March 7, 2019; 73 (5): 915-929.e6.                              

TRAIP is a master regulator of DNA interstrand crosslink repair., Wu RA, Semlow DR, Kamimae-Lanning AN, Kochenova OV, Chistol G, Hodskinson MR, Amunugama R, Sparks JL, Wang M, Deng L, Mimoso CA, Low E, Patel KJ, Walter JC., Nature. March 1, 2019; 567 (7747): 267-272.                          

Claspin - checkpoint adaptor and DNA replication factor., Smits VAJ, Cabrera E, Freire R, Gillespie DA., FEBS J. February 1, 2019; 286 (3): 441-455.

Suppression of targeting of Dbf4-dependent kinase to pre-replicative complex in G0 nuclei., Okada T, Okabe G, Tak YS, Mimura S, Takisawa H, Kubota Y., Genes Cells. February 1, 2018; 23 (2): 94-104.

An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-α to Mcm2-7., Perez-Arnaiz P, Bruck I, Colbert MK, Kaplan DL., Nucleic Acids Res. July 7, 2017; 45 (12): 7261-7275.                

Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1., Alver RC, Chadha GS, Gillespie PJ, Blow JJ., Cell Rep. March 7, 2017; 18 (10): 2508-2520.                

Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation., Gao Y, Yao J, Poudel S, Romer E, Abu-Niaaj L, Leffak M., J Biol Chem. December 26, 2014; 289 (52): 35987-6000.

The role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae., Brandão LN, Ferguson R, Santoro I, Jinks-Robertson S, Sclafani RA., Genetics. August 1, 2014; 197 (4): 1111-22.

Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1., Poh WT, Chadha GS, Gillespie PJ, Kaldis P, Blow JJ., Open Biol. January 8, 2014; 4 (1): 130138.                

Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication., Kundu LR, Seki M, Watanabe N, Murofushi H, Furukohri A, Waga S, Score AJ, Blow JJ, Horikoshi M, Enomoto T, Tada S., Biochim Biophys Acta. June 1, 2011; 1813 (6): 1129-36.

MCM2-7 form double hexamers at licensed origins in Xenopus egg extract., Gambus A, Khoudoli GA, Jones RC, Blow JJ., J Biol Chem. April 1, 2011; 286 (13): 11855-64.                

Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex., Kundu LR, Kumata Y, Kakusho N, Watanabe S, Furukohri A, Waga S, Seki M, Masai H, Enomoto T, Tada S., Nucleic Acids Res. September 1, 2010; 38 (16): 5409-18.              

Drf1-dependent kinase interacts with Claspin through a conserved protein motif., Gold DA, Dunphy WG., J Biol Chem. April 23, 2010; 285 (17): 12638-46.

The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control., Tsuji T, Lau E, Chiang GG, Jiang W., Mol Cell. December 26, 2008; 32 (6): 862-9.

Cdc7-Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts., Takahashi TS, Basu A, Bermudez V, Hurwitz J, Walter JC., Genes Dev. July 15, 2008; 22 (14): 1894-905.            

Xenopus CDC7/DRF1 complex is required for the initiation of DNA replication., Silva T, Bradley RH, Gao Y, Coue M., J Biol Chem. April 28, 2006; 281 (17): 11569-76.

Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint., Petersen P, Chou DM, You Z, Hunter T, Walter JC, Walter G., Mol Cell Biol. March 1, 2006; 26 (5): 1997-2011.

Cdc7-Drf1 is a developmentally regulated protein kinase required for the initiation of vertebrate DNA replication., Takahashi TS, Walter JC., Genes Dev. October 1, 2005; 19 (19): 2295-300.

A novel Cdk2 interactor is phosphorylated by Cdc7 and associates with components of the replication complexes., Grishina I, Lattes B., Cell Cycle. August 1, 2005; 4 (8): 1120-6.

A vertebrate homolog of the cell cycle regulator Dbf4 is an inhibitor of Wnt signaling required for heart development., Brott BK, Sokol SY., Dev Cell. May 1, 2005; 8 (5): 703-15.  

ATM and ATR check in on origins: a dynamic model for origin selection and activation., Shechter D, Gautier J., Cell Cycle. February 1, 2005; 4 (2): 235-8.

ATR and ATM regulate the timing of DNA replication origin firing., Shechter D, Costanzo V, Gautier J., Nat Cell Biol. July 1, 2004; 6 (7): 648-55.

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication., Jares P, Luciani MG, Blow JJ., BMC Mol Biol. June 28, 2004; 5 5.          

Cdc7 kinases (DDKs) and checkpoint responses: lessons from two yeasts., Duncker BP, Brown GW., Mutat Res. November 27, 2003; 532 (1-2): 21-7.

Xenopus Drf1, a regulator of Cdc7, displays checkpoint-dependent accumulation on chromatin during an S-phase arrest., Yanow SK, Gold DA, Yoo HY, Dunphy WG., J Biol Chem. October 17, 2003; 278 (42): 41083-92.

Identification and characterization of a Xenopus homolog of Dbf4, a regulatory subunit of the Cdc7 protein kinase required for the initiation of DNA replication., Furukohri A, Sato N, Masai H, Arai K, Sugino A, Waga S., J Biochem. September 1, 2003; 134 (3): 447-57.

Cyclin-dependent kinases and S phase control in mammalian cells., Woo RA, Poon RY., Cell Cycle. January 1, 2003; 2 (4): 316-24.

An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication., Costanzo V, Shechter D, Lupardus PJ, Cimprich KA, Gottesman M, Gautier J., Mol Cell. January 1, 2003; 11 (1): 203-13.

The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication., Van Hatten RA, Tutter AV, Holway AH, Khederian AM, Walter JC, Michael WM., J Cell Biol. November 25, 2002; 159 (4): 541-7.          

Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex., Chou DM, Petersen P, Walter JC, Walter G., J Biol Chem. October 25, 2002; 277 (43): 40520-7.

MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts., Edwards MC, Tutter AV, Cvetic C, Gilbert CH, Prokhorova TA, Walter JC., J Biol Chem. September 6, 2002; 277 (36): 33049-57.

Control of DNA replication licensing in a cell cycle., Nishitani H, Lygerou Z., Genes Cells. June 1, 2002; 7 (6): 523-34.        

Xic1 degradation in Xenopus egg extracts is coupled to initiation of DNA replication., You Z, Harvey K, Kong L, Newport J., Genes Dev. May 15, 2002; 16 (10): 1182-94.

Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45., Wohlschlegel JA, Dhar SK, Prokhorova TA, Dutta A, Walter JC., Mol Cell. February 1, 2002; 9 (2): 233-40.

Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts., Walter JC., J Biol Chem. December 15, 2000; 275 (50): 39773-8.

Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage., Costanzo V, Robertson K, Ying CY, Kim E, Avvedimento E, Gottesman M, Grieco D, Gautier J., Mol Cell. September 1, 2000; 6 (3): 649-59.

Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading., Jares P, Blow JJ., Genes Dev. June 15, 2000; 14 (12): 1528-40.

Distinct phosphoisoforms of the Xenopus Mcm4 protein regulate the function of the Mcm complex., Pereverzeva I, Whitmire E, Khan B, Coué M., Mol Cell Biol. May 1, 2000; 20 (10): 3667-76.

Protein kinase A is required for chromosomal DNA replication., Costanzo V, Avvedimento EV, Gottesman ME, Gautier J, Grieco D., Curr Biol. August 26, 1999; 9 (16): 903-6.

Cloning and characterization of Chinese hamster CDC7 (ChCDC7)., Guo B, Lee H., Somat Cell Mol Genet. May 1, 1999; 25 (3): 159-71.

Identification and characterization of mouse homologue to yeast Cdc7 protein and chromosomal localization of the cognate mouse gene Cdc7l., Faul T, Staib C, Nanda I, Schmid M, Grummt F., Chromosoma. April 1, 1999; 108 (1): 26-31.

DNA replication in vertebrates requires a homolog of the Cdc7 protein kinase., Roberts BT, Ying CY, Gautier J, Maller JL., Proc Natl Acad Sci U S A. March 16, 1999; 96 (6): 2800-4.

Cyclin-dependent kinases at the G1-S transition of the mammalian cell cycle., Hengstschläger M, Braun K, Soucek T, Miloloza A, Hengstschläger-Ottnad E., Mutat Res. January 1, 1999; 436 (1): 1-9.

Growth regulation of the expression of mouse cDNA and gene encoding a serine/threonine kinase related to Saccharomyces cerevisiae CDC7 essential for G1/S transition. Structure, chromosomal localization, and expression of mouse gene for s. cerevisiae Cdc7-related kinase., Kim JM, Sato N, Yamada M, Arai K, Masai H., J Biol Chem. September 4, 1998; 273 (36): 23248-57.

Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7., Sato N, Arai K, Masai H., EMBO J. July 16, 1997; 16 (14): 4340-51.

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