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Summary Expression Phenotypes Gene Literature (61) GO Terms (23) Nucleotides (354) Proteins (140) Interactants (455) Wiki
XB-GENEPAGE-952024

Papers associated with ptk2



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Adherens junctions stimulate and spatially guide integrin activation and extracellular matrix deposition., Hadjisavva R, Anastasiou O, Ioannou PS, Zheltkova M, Skourides PA., Cell Rep. July 19, 2022; 40 (3): 111091.                              

The mechanosensitive channel Piezo1 cooperates with semaphorins to control neural crest migration., Canales Coutiño B, Mayor R., Development. December 1, 2021; 148 (23):                           

RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis., Kim H, Lee YS, Kim SM, Jang S, Choi H, Lee JW, Kim TD, Kim VN., Dev Cell. April 19, 2021; 56 (8): 1118-1130.e6.                                  

Transcriptomic analysis of the trade-off between endurance and burst-performance in the frog Xenopus allofraseri., Ducret V, Richards AJ, Videlier M, Scalvenzi T, Moore KA, Paszkiewicz K, Bonneaud C, Pollet N, Herrel A., BMC Genomics. March 23, 2021; 22 (1): 204.        

Paradoxical activation of c-Src as a drug-resistant mechanism., Higuchi M, Ishiyama K, Maruoka M, Kanamori R, Takaori-Kondo A, Watanabe N., Cell Rep. March 23, 2021; 34 (12): 108876.  

The Ric-8A/Gα13/FAK signalling cascade controls focal adhesion formation during neural crest cell migration in Xenopus., Toro-Tapia G, Villaseca S, Beyer A, Roycroft A, Marcellini S, Mayor R, Torrejón M., Development. November 21, 2018; 145 (22):                               

Redistribution of Adhesive Forces through Src/FAK Drives Contact Inhibition of Locomotion in Neural Crest., Roycroft A, Szabó A, Bahm I, Daly L, Charras G, Parsons M, Mayor R., Dev Cell. June 4, 2018; 45 (5): 565-579.e3.                                        

Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus., Gonzalez Malagon SG, Lopez Muñoz AM, Doro D, Bolger TG, Poon E, Tucker ER, Adel Al-Lami H, Krause M, Phiel CJ, Chesler L, Liu KJ, Liu KJ., Nat Commun. March 19, 2018; 9 (1): 1126.                  

Protein localization screening in vivo reveals novel regulators of multiciliated cell development and function., Tu F, Sedzinski J, Ma Y, Marcotte EM, Wallingford JB., J Cell Sci. January 29, 2018; 131 (3):             

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z, Lei A, Xu L, Chen L, Chen Y, Chen Y, Zhang X, Gao Y, Yang X, Zhang M, Cao Y, Cao Y., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.        

PKC-mediated phosphorylation of nuclear lamins at a single serine residue regulates interphase nuclear size in Xenopus and mammalian cells., Edens LJ, Dilsaver MR, Levy DL., Mol Biol Cell. May 15, 2017; 28 (10): 1389-1399.          

Calpain-Mediated Proteolysis of Talin and FAK Regulates Adhesion Dynamics Necessary for Axon Guidance., Kerstein PC, Patel KM, Gomez TM., J Neurosci. February 8, 2017; 37 (6): 1568-1580.                

Addressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells., Antoniades I, Stylianou P, Christodoulou N, Skourides PA., J Biol Chem. January 13, 2017; 292 (2): 488-504.              

EphA7 modulates apical constriction of hindbrain neuroepithelium during neurulation in Xenopus., Wang X, Sun J, Li C, Mao B., Biochem Biophys Res Commun. October 28, 2016; 479 (4): 759-765.        

Novel O-GlcNAcylation on Ser(40) of canonical H2A isoforms specific to viviparity., Hirosawa M, Hayakawa K, Yoneda C, Arai D, Shiota H, Suzuki T, Tanaka S, Dohmae N, Shiota K., Sci Rep. September 12, 2016; 6 31785.          

Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces., Scarpa E, Szabó A, Bibonne A, Theveneau E, Parsons M, Mayor R., Dev Cell. August 24, 2015; 34 (4): 421-34.                                            

Regulation of ECM degradation and axon guidance by growth cone invadosomes., Santiago-Medina M, Gregus KA, Nichol RH, O'Toole SM, Gomez TM., Development. February 1, 2015; 142 (3): 486-96.                        

FAK is required for tension-dependent organization of collective cell movements in Xenopus mesendoderm., Bjerke MA, Dzamba BJ, Wang C, DeSimone DW., Dev Biol. October 15, 2014; 394 (2): 340-56.                        

FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis., Petridou NI, Skourides PA., Nat Commun. January 1, 2014; 5 5240.      

A dominant-negative provides new insights into FAK regulation and function in early embryonic morphogenesis., Petridou NI, Stylianou P, Skourides PA., Development. October 1, 2013; 140 (20): 4266-76.

The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis., Samwer M, Dehne HJ, Spira F, Kollmar M, Gerlich DW, Urlaub H, Görlich D., EMBO J. July 3, 2013; 32 (13): 1886-902.              

Focal adhesion kinase modulates Cdc42 activity downstream of positive and negative axon guidance cues., Myers JP, Robles E, Ducharme-Smith A, Gomez TM., J Cell Sci. June 15, 2012; 125 (Pt 12): 2918-29.

Activation of endogenous FAK via expression of its amino terminal domain in Xenopus embryos., Petridou NI, Stylianou P, Christodoulou N, Rhoads D, Guan JL, Skourides PA., PLoS One. January 1, 2012; 7 (8): e42577.            

Bidirectional remodeling of β1-integrin adhesions during chemotropic regulation of nerve growth., Carlstrom LP, Hines JH, Henle SJ, Henley JR., BMC Biol. November 30, 2011; 9 82.              

Focal adhesion kinase promotes integrin adhesion dynamics necessary for chemotropic turning of nerve growth cones., Myers JP, Gomez TM., J Neurosci. September 21, 2011; 31 (38): 13585-95.

FAK and WNT signaling: the meeting of two pathways in cancer and development., Fonar Y, Frank D., Anticancer Agents Med Chem. September 1, 2011; 11 (7): 600-6.

Focal adhesion kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate., Fonar Y, Gutkovich YE, Root H, Malyarova A, Aamar E, Golubovskaya VM, Elias S, Elkouby YM, Frank D., Mol Biol Cell. July 1, 2011; 22 (13): 2409-21.                  

Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E., Kim Y, Holland AJ, Lan W, Cleveland DW., Cell. August 6, 2010; 142 (3): 444-55.          

Focal adhesion kinase is essential for cardiac looping and multichamber heart formation., Doherty JT, Conlon FL, Mack CP, Taylor JM., Genesis. August 1, 2010; 48 (8): 492-504.                  

Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape., Jolly AL, Kim H, Srinivasan D, Lakonishok M, Larson AG, Gelfand VI., Proc Natl Acad Sci U S A. July 6, 2010; 107 (27): 12151-6.

Retinotopic mapping requires focal adhesion kinase-mediated regulation of growth cone adhesion., Woo S, Rowan DJ, Gomez TM., J Neurosci. November 4, 2009; 29 (44): 13981-91.                

Ca(2+) regulates the subcellular localization of adenomatous polyposis coli tumor suppressor protein., Togo T., Biochem Biophys Res Commun. October 9, 2009; 388 (1): 12-6.        

Imaging morphogenesis, in Xenopus with Quantum Dot nanocrystals., Stylianou P, Skourides PA., Mech Dev. October 1, 2009; 126 (10): 828-41.          

Antibody microarray analyses of signal transduction protein expression and phosphorylation during porcine oocyte maturation., Pelech S, Jelinkova L, Susor A, Zhang H, Shi X, Pavlok A, Kubelka M, Kovarova H., J Proteome Res. July 1, 2008; 7 (7): 2860-71.

ZRP-1 controls Rho GTPase-mediated actin reorganization by localizing at cell-matrix and cell-cell adhesions., Bai CY, Ohsugi M, Abe Y, Yamamoto T., J Cell Sci. August 15, 2007; 120 (Pt 16): 2828-37.

Focal adhesion kinase signaling at sites of integrin-mediated adhesion controls axon pathfinding., Robles E, Gomez TM., Nat Neurosci. October 1, 2006; 9 (10): 1274-83.

Alphavbeta3 integrin and cofilin modulate K1735 melanoma cell invasion., Dang D, Bamburg JR, Ramos DM., Exp Cell Res. February 15, 2006; 312 (4): 468-77.

Regulation of somitogenesis by Ena/VASP proteins and FAK during Xenopus development., Kragtorp KA, Miller JR., Development. February 1, 2006; 133 (4): 685-95.                  

Deciphering protein function during mitosis in PtK cells using RNAi., Stout JR, Rizk RS, Kline SL, Walczak CE., BMC Cell Biol. January 19, 2006; 7 26.          

Local calcium transients contribute to disappearance of pFAK, focal complex removal and deadhesion of neuronal growth cones and fibroblasts., Conklin MW, Lin MS, Spitzer NC., Dev Biol. November 1, 2005; 287 (1): 201-12.                

Activation of FAK and Src are receptor-proximal events required for netrin signaling., Li W, Lee J, Vikis HG, Lee SH, Liu G, Aurandt J, Shen TL, Fearon ER, Guan JL, Han M, Rao Y, Hong K, Guan KL., Nat Neurosci. November 1, 2004; 7 (11): 1213-21.

Down-regulation of RNA helicase II/Gu results in the depletion of 18 and 28 S rRNAs in Xenopus oocyte., Yang H, Zhou J, Ochs RL, Henning D, Jin R, Valdez BC., J Biol Chem. October 3, 2003; 278 (40): 38847-59.

Adhesive crosstalk in gastrulation., Montero JA, Heisenberg CP., Dev Cell. August 1, 2003; 5 (2): 190-1.

Integrin-ECM interactions regulate cadherin-dependent cell adhesion and are required for convergent extension in Xenopus., Marsden M, DeSimone DW., Curr Biol. July 15, 2003; 13 (14): 1182-91.                  

SETA/CIN85/Ruk and its binding partner AIP1 associate with diverse cytoskeletal elements, including FAKs, and modulate cell adhesion., Schmidt MHH, Chen B, Randazzo LM, Bogler O., J Cell Sci. July 15, 2003; 116 (Pt 14): 2845-55.

Poplar potassium transporters capable of controlling K+ homeostasis and K+-dependent xylogenesis., Langer K, Ache P, Geiger D, Stinzing A, Arend M, Wind C, Regan S, Fromm J, Hedrich R., Plant J. December 1, 2002; 32 (6): 997-1009.

Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography., Nowakowski J, Cronin CN, McRee DE, Knuth MW, Nelson CG, Pavletich NP, Rogers J, Sang BC, Scheibe DN, Swanson RV, Thompson DA., Structure. December 1, 2002; 10 (12): 1659-67.

Assembly of centrosomal proteins and microtubule organization depends on PCM-1., Dammermann A, Merdes A., J Cell Biol. October 28, 2002; 159 (2): 255-66.                

The microtubule-destabilizing kinesin XKCM1 regulates microtubule dynamic instability in cells., Kline-Smith SL, Walczak CE., Mol Biol Cell. August 1, 2002; 13 (8): 2718-31.

Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells., Daigle N, Beaudouin J, Hartnell L, Imreh G, Hallberg E, Lippincott-Schwartz J, Ellenberg J., J Cell Biol. July 9, 2001; 154 (1): 71-84.            

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