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Summary Expression Phenotypes Gene Literature (99) GO Terms (3) Nucleotides (574) Proteins (69) Interactants (302) Wiki
XB-GENEPAGE-974719

Papers associated with cdc6



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Unraveling the interplay between PKA inhibition and Cdk1 activation during oocyte meiotic maturation., Santoni M, Meneau F, Sekhsoukh N, Castella S, Le T, Miot M, Daldello EM., Cell Rep. February 27, 2024; 43 (2): 113782.                  

Solubility phase transition of maternal RNAs during vertebrate oocyte-to-embryo transition., Hwang H, Chen S, Ma M, Divyanshi, Fan HC, Borwick E, Böke E, Mei W, Yang J., Dev Cell. December 4, 2023; 58 (23): 2776-2788.e5.                          

CDC6 as a Key Inhibitory Regulator of CDK1 Activation Dynamics and the Timing of Mitotic Entry and Progression., El Dika M, Dudka D, Kloc M, Kubiak JZ., Biology (Basel). June 14, 2023; 12 (6):       

Inhibition of DNA replication initiation by silver nanoclusters., Tao Y, Aparicio T, Li M, Leong KW, Zha S, Gautier J., Nucleic Acids Res. May 21, 2021; 49 (9): 5074-5083.                        

Studying chromosome biology with single-molecule resolution in Xenopus laevis egg extracts., Cameron G, Yardimci H., Essays Biochem. April 16, 2021; 65 (1): 17-26.        

Mitotic timing is differentially controlled by A- and B-type cyclins and by CDC6 associated with a bona fide CDK inhibitor Xic1 in Xenopus laevis cell-free extract., El Dika M, Wechselberger L, Djeghout B, Benouareth DE, Jęderka K, Lewicki S, Zdanowski R, Prigent C, Kloc M, Kubiak JZ., Int J Dev Biol. January 1, 2021; 65 (7-8-9): 487-496.          

Mathematical Model Explaining the Role of CDC6 in the Diauxic Growth of CDK1 Activity during the M-Phase of the Cell Cycle., Dębowski M, Szymańska Z, Kubiak JZ, Lachowicz M., Cells. November 28, 2019; 8 (12):                 

Claspin - checkpoint adaptor and DNA replication factor., Smits VAJ, Cabrera E, Freire R, Gillespie DA., FEBS J. February 1, 2019; 286 (3): 441-455.

Expression variation and covariation impair analog and enable binary signaling control., Kovary KM, Taylor B, Zhao ML, Teruel MN., Mol Syst Biol. May 14, 2018; 14 (5): e7997.                            

Correction: Control of Cdc6 accumulation by Cdk1 and MAPK is essential for completion of oocyte meiotic divisions in Xenopus (doi:10.1242/jcs.166553)., Daldello EM, Le T, Poulhe R, Jessus C, Haccard O, Dupré A., J Cell Sci. February 1, 2018; 131 (3):


MCM interference during licensing of DNA replication in Xenopus egg extracts-Possible Role of a C-terminal region of MCM3., Mimura S, Kubota Y, Takisawa H., Cell Cycle. January 1, 2018; 17 (4): 492-505.

Phosphorylation Dynamics Dominate the Regulated Proteome during Early Xenopus Development., Peuchen EH, Cox OF, Sun L, Hebert AS, Coon JJ, Champion MM, Dovichi NJ, Huber PW., Sci Rep. November 15, 2017; 7 (1): 15647.                          

The stability of Fbw7α in M-phase requires its phosphorylation by PKC., Zitouni S, Méchali F, Papin C, Choquet A, Roche D, Baldin V, Coux O, Bonne-Andrea C., PLoS One. August 29, 2017; 12 (8): e0183500.            

The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines., Gardner NJ, Gillespie PJ, Carrington JT, Shanks EJ, McElroy SP, Haagensen EJ, Frearson JA, Woodland A, Blow JJ., Cell Chem Biol. August 17, 2017; 24 (8): 981-992.e4.                        

Rethinking origin licensing., Bell SP., Elife. January 19, 2017; 6   

Role of Cdc6 During Oogenesis and Early Embryo Development in Mouse and Xenopus laevis., Borsuk E, Jachowicz J, Kloc M, Tassan JP, Kubiak JZ., Results Probl Cell Differ. January 1, 2017; 59 201-211.

Studying essential DNA metabolism proteins in Xenopus egg extract., Sannino V, Kolinjivadi AM, Baldi G, Costanzo V., Int J Dev Biol. January 1, 2016; 60 (7-8-9): 221-227.

Control of Cdc6 accumulation by Cdk1 and MAPK is essential for completion of oocyte meiotic divisions in Xenopus., Daldello EM, Le T, Poulhe R, Jessus C, Haccard O, Dupré A., J Cell Sci. July 15, 2015; 128 (14): 2482-96.

RecQ4 promotes the conversion of the pre-initiation complex at a site-specific origin for DNA unwinding in Xenopus egg extracts., Sanuki Y, Kubota Y, Kanemaki MT, Takahashi TS, Mimura S, Takisawa H., Cell Cycle. January 1, 2015; 14 (7): 1010-23.

CDC6 controls dynamics of the first embryonic M-phase entry and progression via CDK1 inhibition., El Dika M, Laskowska-Kaszub K, Koryto M, Dudka D, Prigent C, Tassan JP, Kloc M, Polanski Z, Borsuk E, Kubiak JZ., Dev Biol. December 1, 2014; 396 (1): 67-80.                  

New insights into the maternal to zygotic transition., Langley AR, Smith JC, Stemple DL, Harvey SA., Development. October 1, 2014; 141 (20): 3834-41.

Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration., Bernis C, Swift-Taylor B, Nord M, Carmona S, Chook YM, Forbes DJ., Mol Biol Cell. April 1, 2014; 25 (7): 992-1009.                  

Quantitative proteomics of Xenopus laevis embryos: expression kinetics of nearly 4000 proteins during early development., Sun L, Bertke MM, Champion MM, Zhu G, Huber PW, Dovichi NJ., Sci Rep. February 26, 2014; 4 4365.                              

Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1., Poh WT, Chadha GS, Gillespie PJ, Kaldis P, Blow JJ., Open Biol. January 8, 2014; 4 (1): 130138.                

Titration of four replication factors is essential for the Xenopus laevis midblastula transition., Collart C, Allen GE, Bradshaw CR, Smith JC, Zegerman P., Science. August 23, 2013; 341 (6148): 893-6.

Mcm8 and Mcm9 form a dimeric complex in Xenopus laevis egg extract that is not essential for DNA replication initiation., Gambus A, Blow JJ., Cell Cycle. April 15, 2013; 12 (8): 1225-32.                

SUMO2/3 modification of cyclin E contributes to the control of replication origin firing., Bonne-Andrea C, Kahli M, Mechali F, Lemaitre JM, Bossis G, Coux O., Nat Commun. January 1, 2013; 4 1850.        

Cdc6 is required for meiotic spindle assembly in Xenopus oocytes., Narasimhachar Y, Webster DR, Gard DL, Coué M., Cell Cycle. February 1, 2012; 11 (3): 524-31.

Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos., Kisielewska J, Blow JJ., Development. January 1, 2012; 139 (1): 63-74.              

Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication., Kundu LR, Seki M, Watanabe N, Murofushi H, Furukohri A, Waga S, Score AJ, Blow JJ, Horikoshi M, Enomoto T, Tada S., Biochim Biophys Acta. June 1, 2011; 1813 (6): 1129-36.

Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells., Munkley J, Copeland NA, Moignard V, Knight JR, Greaves E, Ramsbottom SA, Pownall ME, Southgate J, Ainscough JF, Coverley D., Nucleic Acids Res. April 1, 2011; 39 (7): 2671-7.        

Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex., Kundu LR, Kumata Y, Kakusho N, Watanabe S, Furukohri A, Waga S, Seki M, Masai H, Enomoto T, Tada S., Nucleic Acids Res. September 1, 2010; 38 (16): 5409-18.              

Recruitment of Orc6l, a dormant maternal mRNA in mouse oocytes, is essential for DNA replication in 1-cell embryos., Murai S, Stein P, Buffone MG, Yamashita S, Schultz RM., Dev Biol. May 1, 2010; 341 (1): 205-12.

Replication origins and timing of temporal replication in budding yeast: how to solve the conundrum?, Barberis M, Spiesser TW, Klipp E., Curr Genomics. May 1, 2010; 11 (3): 199-211.          

CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells., Yoshida K, Sugimoto N, Iwahori S, Yugawa T, Narisawa-Saito M, Kiyono T, Fujita M., J Cell Sci. January 15, 2010; 123 (Pt 2): 225-35.

Origin-dependent initiation of DNA replication within telomeric sequences., Kurth I, Gautier J., Nucleic Acids Res. January 1, 2010; 38 (2): 467-76.          

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication., Evrin C, Clarke P, Zech J, Lurz R, Sun J, Uhle S, Li H, Stillman B, Speck C., Proc Natl Acad Sci U S A. December 1, 2009; 106 (48): 20240-5.

Replication initiation complex formation in the absence of nuclear function in Xenopus., Krasinska L, Fisher D., Nucleic Acids Res. April 1, 2009; 37 (7): 2238-48.            

Identification of an arginine-rich motif in human papillomavirus type 1 E1;E4 protein necessary for E4-mediated inhibition of cellular DNA synthesis in vitro and in cells., Roberts S, Kingsbury SR, Stoeber K, Knight GL, Gallimore PH, Williams GH., J Virol. September 1, 2008; 82 (18): 9056-64.

Cdt1 and geminin: role during cell cycle progression and DNA damage in higher eukaryotes., Tada S., Front Biosci. January 1, 2007; 12 1629-41.

Dynamics of DNA binding of replication initiation proteins during de novo formation of pre-replicative complexes in Xenopus egg extracts., Waga S, Zembutsu A., J Biol Chem. April 21, 2006; 281 (16): 10926-34.

Regulation of replication licensing by acetyltransferase Hbo1., Iizuka M, Matsui T, Takisawa H, Smith MM., Mol Cell Biol. February 1, 2006; 26 (3): 1098-108.

Phosphorylation of maskin by Aurora-A participates in the control of sequential protein synthesis during Xenopus laevis oocyte maturation., Pascreau G, Delcros JG, Cremet JY, Prigent C, Arlot-Bonnemains Y., J Biol Chem. April 8, 2005; 280 (14): 13415-23.

Licensing for DNA replication requires a strict sequential assembly of Cdc6 and Cdt1 onto chromatin in Xenopus egg extracts., Tsuyama T, Tada S, Watanabe S, Seki M, Enomoto T., Nucleic Acids Res. February 1, 2005; 33 (2): 765-75.            

Recombinant Cdt1 induces rereplication of G2 nuclei in Xenopus egg extracts., Maiorano D, Krasinska L, Lutzmann M, Mechali M., Curr Biol. January 26, 2005; 15 (2): 146-53.

Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus., Li A, Blow JJ., EMBO J. January 26, 2005; 24 (2): 395-404.

Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts., Arias EE, Walter JC., Genes Dev. January 1, 2005; 19 (1): 114-26.

DNA replication licensing in somatic and germ cells., Eward KL, Obermann EC, Shreeram S, Loddo M, Fanshawe T, Williams C, Jung HI, Prevost AT, Blow JJ, Stoeber K, Williams GH., J Cell Sci. November 15, 2004; 117 (Pt 24): 5875-86.

Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex., Takahashi TS, Yiu P, Chou MF, Gygi S, Walter JC., Nat Cell Biol. October 1, 2004; 6 (10): 991-6.

The regulation of competence to replicate in meiosis by Cdc6 is conserved during evolution., Lemaître JM, Bocquet S, Terret ME, Namdar M, Aït-Ahmed O, Kearsey S, Verlhac MH, Méchali M., Mol Reprod Dev. September 1, 2004; 69 (1): 94-100.

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