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Summary Expression Phenotypes Gene Literature (70) GO Terms (15) Nucleotides (222) Proteins (46) Interactants (140) Wiki

Papers associated with cav2

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Direct inhibition of CaV2.3 by Gem is dynamin dependent and does not require a direct alfa/beta interaction., Contreras GF, Saavedra J, Navarro-Quezada N, Mellado G, Gonzalez C, Neely A., Biochem Biophys Res Commun. January 1, 2022; 586 107-113.

Association of A Novel Splice Site Mutation in P/Q-Type Calcium Channels with Childhood Epilepsy and Late-Onset Slowly Progressive Non-Episodic Cerebellar Ataxia., Stendel C, D'Adamo MC, Wiessner M, Dusl M, Cenciarini M, Belia S, Nematian-Ardestani E, Bauer P, Senderek J, Klopstock T, Pessia M., Int J Mol Sci. May 27, 2020; 21 (11):             

Cav2.1 C-terminal fragments produced in Xenopus laevis oocytes do not modify the channel expression and functional properties., Ménard C, Charnet P, Rousset M, Vignes M, Cens T., Eur J Neurosci. May 1, 2020; 51 (9): 1900-1913.            

A Selectivity Filter Gate Controls Voltage-Gated Calcium Channel Calcium-Dependent Inactivation., Abderemane-Ali F, Findeisen F, Rossen ND, Minor DL., Neuron. March 20, 2019; 101 (6): 1134-1149.e3.

Cloning, Synthesis and Functional Characterization of a Novel α-Conotoxin Lt1.3., Chen J, Liang L, Ning H, Cai F, Liu Z, Zhang L, Zhou L, Dai Q., Mar Drugs. March 31, 2018; 16 (4):             

A novel α-conopeptide Eu1.6 inhibits N-type (CaV2.2) calcium channels and exhibits potent analgesic activity., Liu Z, Bartels P, Sadeghi M, Du T, Dai Q, Zhu C, Yu S, Wang S, Dong M, Sun T, Guo J, Peng S, Jiang L, Adams DJ, Dai Q., Sci Rep. January 17, 2018; 8 (1): 1004.                

Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel., Zhang K, Zhao Z, Lan L, Wei X, Wang L, Liu X, Yan H, Zheng J., Front Pharmacol. May 26, 2017; 8 302.              

Ubiquitin Ligase RNF138 Promotes Episodic Ataxia Type 2-Associated Aberrant Degradation of Human Cav2.1 (P/Q-Type) Calcium Channels., Fu SJ, Jeng CJ, Ma CH, Peng YJ, Lee CM, Fang YC, Lee YC, Tang SC, Hu MC, Tang CY., J Neurosci. March 1, 2017; 37 (9): 2485-2503.

Honeybee locomotion is impaired by Am-CaV3 low voltage-activated Ca2+ channel antagonist., Rousset M, Collet C, Cens T, Bastin F, Raymond V, Massou I, Menard C, Thibaud JB, Charreton M, Vignes M, Chahine M, Sandoz JC, Charnet P., Sci Rep. February 1, 2017; 7 41782.        

Selective pressure modulation of synaptic voltage-dependent calcium channels-involvement in HPNS mechanism., Aviner B, Gradwohl G, Bliznyuk A, Grossman Y., J Cell Mol Med. October 1, 2016; 20 (10): 1872-88.                  

A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of CaV2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca2+ Influx., Bahamonde MI, Serra SA, Drechsel O, Rahman R, Marcé-Grau A, Prieto M, Ossowski S, Macaya A, Fernández-Fernández JM., PLoS One. December 1, 2015; 10 (12): e0146035.                

Bioelectric memory: modeling resting potential bistability in amphibian embryos and mammalian cells., Law R, Levin M., Plant Physiol. October 15, 2015; 12 22.            

Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3., Park SJ, Min SH, Kang HW, Lee JH., Biochim Biophys Acta. October 1, 2015; 1848 (10 Pt A): 2092-100.

Regulation of neuronal high-voltage activated Ca(V)2 Ca(2+) channels by the small GTPase RhoA., Rousset M, Cens T, Menard C, Bowerman M, Bellis M, Brusés J, Raoul C, Scamps F, Charnet P., Neuropharmacology. October 1, 2015; 97 201-9.

Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1., Yu R, Seymour VA, Berecki G, Jia X, Akcan M, Adams DJ, Kaas Q, Craik DJ., Sci Rep. August 20, 2015; 5 13264.            

ZC88, a novel N-type calcium channel blocker from 4-amino-piperidine derivatives state-dependent inhibits Cav2.2 calcium channels., Zhang S, Yang L, Zhang K, Liu X, Dai W, Zhang C, Yong Z, Li J, Zheng J., Brain Res. April 24, 2015; 1605 12-21.

Molecular characterization and functional expression of the Apis mellifera voltage-dependent Ca2+ channels., Cens T, Rousset M, Collet C, Charreton M, Garnery L, Le Conte Y, Chahine M, Sandoz JC, Charnet P., Insect Biochem Mol Biol. March 1, 2015; 58 12-27.

Inhibition of protein kinase C (PKC) response of voltage-gated calcium (Cav)2.2 channels expressed in Xenopus oocytes by Cavβ subunits., Rajagopal S, Fields BL, Burton BK, On C, Reeder AA, Kamatchi GL., Neuroscience. November 7, 2014; 280 1-9.

The role of voltage-gated calcium channels in neurotransmitter phenotype specification: Coexpression and functional analysis in Xenopus laevis., Lewis BB, Miller LE, Herbst WA, Saha MS., J Comp Neurol. August 1, 2014; 522 (11): 2518-31.                          

Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels., Berecki G, Daly NL, Huang YH, Vink S, Craik DJ, Alewood PF, Adams DJ., Br J Pharmacol. July 1, 2014; 171 (13): 3313-27.

Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels., Klint JK, Berecki G, Durek T, Mobli M, Knapp O, King GF, Adams DJ, Alewood PF, Rash LD., Biochem Pharmacol. May 15, 2014; 89 (2): 276-86.

The inhibition of functional expression of calcium channels by prion protein demonstrates competition with α2δ for GPI-anchoring pathways., Alvarez-Laviada A, Kadurin I, Senatore A, Chiesa R, Dolphin AC., Biochem J. March 1, 2014; 458 (2): 365-74.          

Lipid modulation of calcium flux through CaV2.3 regulates acrosome exocytosis and fertilization., Cohen R, Buttke DE, Asano A, Mukai C, Nelson JL, Ren D, Miller RJ, Cohen-Kutner M, Atlas D, Travis AJ., Dev Cell. February 10, 2014; 28 (3): 310-21.

Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors., Grishin AA, Cuny H, Hung A, Clark RJ, Brust A, Akondi K, Alewood PF, Craik DJ, Adams DJ., J Biol Chem. November 29, 2013; 288 (48): 34428-42.

Tuning voltage-gated channel activity and cellular excitability with a sphingomyelinase., Combs DJ, Shin HG, Xu Y, Xu Y, Ramu Y, Lu Z., J Gen Physiol. October 1, 2013; 142 (4): 367-80.                    

Characterization of the first honeybee Ca²⁺ channel subunit reveals two novel species- and splicing-specific modes of regulation of channel inactivation., Cens T, Rousset M, Collet C, Raymond V, Démares F, Quintavalle A, Bellis M, Le Conte Y, Chahine M, Charnet P., Pflugers Arch. July 1, 2013; 465 (7): 985-96.

Two sets of amino acids of the domain I of Cav2.3 Ca(2+) channels contribute to their high sensitivity to extracellular protons., Cens T, Rousset M, Charnet P., Pflugers Arch. August 1, 2011; 462 (2): 303-14.

Effects of isoflurane on the expressed Cav2.2 currents in Xenopus oocytes depend on the activation of protein kinase Cδ and its phosphorylation sites in the Cav2.2α1 subunits., Rajagopal S, Fang H, Lynch C, Sando JJ, Kamatchi GL., Neuroscience. May 19, 2011; 182 232-40.

A post-burst after depolarization is mediated by group i metabotropic glutamate receptor-dependent upregulation of Ca(v)2.3 R-type calcium channels in CA1 pyramidal neurons., Park JY, Remy S, Varela J, Cooper DC, Chung S, Kang HW, Lee JH, Spruston N., PLoS Biol. November 16, 2010; 8 (11): e1000534.                    

N terminus is key to the dominant negative suppression of Ca(V)2 calcium channels: implications for episodic ataxia type 2., Page KM, Heblich F, Margas W, Pratt WS, Nieto-Rostro M, Chaggar K, Sandhu K, Davies A, Dolphin AC., J Biol Chem. January 8, 2010; 285 (2): 835-44.              

Swapping the I-II intracellular linker between L-type CaV1.2 and R-type CaV2.3 high-voltage gated calcium channels exchanges activation attributes., Gonzalez-Gutierrez G, Miranda-Laferte E, Contreras G, Neely A, Hidalgo P., Channels (Austin). January 1, 2010; 4 (1): 42-50.

CaV2.1 (P/Q channel) interaction with synaptic proteins is essential for depolarization-evoked release., Cohen-Kutner M, Nachmanni D, Atlas D., Channels (Austin). January 1, 2010; 4 (4): 266-77.

Cloning and characterization of voltage-gated calcium channel alpha1 subunits in Xenopus laevis during development., Lewis BB, Wester MR, Miller LE, Nagarkar MD, Johnson MB, Saha MS., Dev Dyn. November 1, 2009; 238 (11): 2891-902.                                

RGK GTPase-dependent CaV2.1 Ca2+ channel inhibition is independent of CaVbeta-subunit-induced current potentiation., Leyris JP, Gondeau C, Charnet A, Delattre C, Rousset M, Cens T, Charnet P., FASEB J. August 1, 2009; 23 (8): 2627-38.

Use-dependent block of voltage-gated Cav2.1 Ca2+ channels by petasins and eudesmol isomers., Horak S, Koschak A, Stuppner H, Striessnig J., J Pharmacol Exp Ther. July 1, 2009; 330 (1): 220-6.

Disruption of the IS6-AID linker affects voltage-gated calcium channel inactivation and facilitation., Findeisen F, Minor DL., J Gen Physiol. March 1, 2009; 133 (3): 327-43.              

The stargazin-related protein gamma 7 interacts with the mRNA-binding protein heterogeneous nuclear ribonucleoprotein A2 and regulates the stability of specific mRNAs, including CaV2.2., Ferron L, Davies A, Page KM, Cox DJ, Leroy J, Waithe D, Butcher AJ, Sellaturay P, Bolsover S, Pratt WS, Moss FJ, Dolphin AC., J Neurosci. October 15, 2008; 28 (42): 10604-17.

Premature stop codons in a facilitating EF-hand splice variant of CaV2.1 cause episodic ataxia type 2., Graves TD, Imbrici P, Kors EE, Terwindt GM, Eunson LH, Frants RR, Haan J, Ferrari MD, Goadsby PJ, Hanna MG, van den Maagdenberg AM, Kullmann DM., Neurobiol Dis. October 1, 2008; 32 (1): 10-5.

Alternative splicing of the Ca2+ channel beta4 subunit confers specificity for gabapentin inhibition of Cav2.1 trafficking., Mich PM, Horne WA., Mol Pharmacol. September 1, 2008; 74 (3): 904-12.

Repolarizing responses of BKCa-Cav complexes are distinctly shaped by their Cav subunits., Berkefeld H, Fakler B., J Neurosci. August 13, 2008; 28 (33): 8238-45.

The separation of antagonist from agonist effects of trisubstituted purines on CaV2.2 (N-type) channels., Buraei Z, Elmslie KS., J Neurochem. May 1, 2008; 105 (4): 1450-61.

Neurite outgrowth and in vivo sensory innervation mediated by a Ca(V)2.2-laminin beta 2 stop signal., Sann SB, Xu L, Nishimune H, Sanes JR, Spitzer NC., J Neurosci. March 5, 2008; 28 (10): 2366-74.                

Reconstitution of depolarization and Ca2+-evoked secretion in Xenopus oocytes monitored by membrane capacitance., Cohen R, Schmitt BM, Atlas D., Methods Mol Biol. January 1, 2008; 440 269-82.

Histidine residues in the IS3-IS4 loop are critical for nickel-sensitive inhibition of the Cav2.3 calcium channel., Kang HW, Moon HJ, Joo SH, Lee JH, Lee JH., FEBS Lett. December 22, 2007; 581 (30): 5774-80.

Depolarization-evoked secretion requires two vicinal transmembrane cysteines of syntaxin 1A., Cohen R, Marom M, Atlas D., PLoS One. December 5, 2007; 2 (12): e1273.                

The role of distal S6 hydrophobic residues in the voltage-dependent gating of CaV2.3 channels., Raybaud A, Baspinar EE, Dionne F, Dodier Y, Sauvé R, Parent L., J Biol Chem. September 21, 2007; 282 (38): 27944-52.

Activation of protein kinase C augments T-type Ca2+ channel activity without changing channel surface density., Park JY, Kang HW, Moon HJ, Huh SU, Jeong SW, Soldatov NM, Lee JH., J Physiol. December 1, 2006; 577 (Pt 2): 513-23.

BKCa-Cav channel complexes mediate rapid and localized Ca2+-activated K+ signaling., Berkefeld H, Sailer CA, Bildl W, Rohde V, Thumfart JO, Eble S, Klugbauer N, Reisinger E, Bischofberger J, Oliver D, Knaus HG, Schulte U, Fakler B., Science. October 27, 2006; 314 (5799): 615-20.

Dominant-negative effects of human P/Q-type Ca2+ channel mutations associated with episodic ataxia type 2., Jeng CJ, Chen YT, Chen YW, Tang CY., Am J Physiol Cell Physiol. April 1, 2006; 290 (4): C1209-20.

Alternative splicing of the voltage-gated Ca2+ channel beta4 subunit creates a uniquely folded N-terminal protein binding domain with cell-specific expression in the cerebellar cortex., Vendel AC, Terry MD, Striegel AR, Iverson NM, Leuranguer V, Rithner CD, Lyons BA, Pickard GE, Tobet SA, Horne WA., J Neurosci. March 8, 2006; 26 (10): 2635-44.

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