pold1 Phenotypes

Phenotypes

XB-GENEPAGE-1002130

Gene Symbol: pold1 Gene Name: polymerase (DNA directed), delta 1, catalytic subunit

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (32 sources): Adenocarcinoma of the colon, Adenomatous colonic polyposis, Brain neoplasm, Breast carcinoma, Carcinoma, Colorectal polyposis, Convex nasal ridge, Cryptorchidism, Dental crowding, Dermal atrophy, Diabetes mellitus, Elevated circulating hepatic transaminase concentration, Endometrial carcinoma, Flexion contracture, Hepatic steatosis, Hepatomegaly, High pitched voice, Hypertriglyceridemia, Hypogonadism, Insulin resistance, Kyphosis, Lack of skin elasticity, Lipodystrophy, Micrognathia, Narrow mouth, Neoplasm of the rectum, Osteoporosis, Proptosis, Scleroderma, Scoliosis, Sensorineural hearing impairment, Telangiectasia [+]
Mouse (15 sources): abnormal trophoblast layer morphology, absent inner cell mass proliferation, embryo phenotype, embryonic lethality between implantation and somite formation, complete penetrance, embryonic lethality between somite formation and embryo turning, complete penetrance, embryonic lethality during organogenesis, complete penetrance, enlarged thymus, increased T cell derived lymphoma incidence, increased intestinal adenoma incidence, increased lung tumor incidence, increased lymphoma incidence, increased skin tumor incidence, increased tumor incidence, inner cell mass degeneration, premature death [+]
View all ortholog results at Monarch