hmox1 Phenotypes

Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Phenotypes

Gene Literature (7)

Nucleotides (209)

Interactants (244)

XB-GENEPAGE-1002242

Gene Symbol: hmox1 Gene Name: heme oxygenase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: hmox1 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (5 sources): Growth delay, Hematuria, Hemolytic anemia, Hepatomegaly, Proteinuria
Mouse (67 sources): abnormal artery morphology, abnormal cardiac muscle contractility, abnormal cellular respiration, abnormal craniofacial morphology, abnormal limb morphology, abnormal lymph node cell ratio, abnormal mitochondrial physiology, abnormal placenta morphology, abnormal placenta vasculature, abnormal redox activity, abnormal response to cardiac infarction, abnormal splenic cell ratio, abnormal thrombosis, abnormal vascular smooth muscle physiology, cardiac fibrosis, chronic inflammation, decreased body size, decreased circulating alanine transaminase level, decreased circulating aspartate transaminase level, decreased circulating free fatty acids level, decreased circulating iron level, decreased erythrocyte cell number, decreased fat cell size, decreased hematocrit, decreased hemoglobin content, decreased interferon-beta secretion, decreased interleukin-1 beta secretion, decreased interleukin-6 secretion, decreased locomotor activity, decreased mean corpuscular volume, decreased susceptibility to Paramyxoviridae infection, decreased susceptibility to bacterial infection induced morbidity/mortality, decreased susceptibility to hepatic steatosis, decreased susceptibility to weight gain, decreased tumor necrosis factor secretion, enlarged lymph nodes, glomerular crescent, homeostasis/metabolism phenotype, improved glucose tolerance, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased cardiomyocyte apoptosis, increased circulating alanine transaminase level, increased circulating ferritin level, increased circulating tumor necrosis factor level, increased energy expenditure, increased granulocyte number, increased heart right ventricle weight, increased insulin sensitivity, increased interferon-gamma secretion, increased macrophage cell number, increased myocardial infarct size, increased renal tubule apoptosis, increased splenocyte proliferation, increased susceptibility to experimental autoimmune encephalomyelitis, increased susceptibility to parasitic infection, increased susceptibility to parasitic infection induced morbidity/mortality, oxidative stress, perinatal lethality, incomplete penetrance, poor grooming, postnatal lethality, incomplete penetrance, premature death, prenatal lethality, complete penetrance, preweaning lethality, incomplete penetrance, proximal convoluted tubule brush border loss, renal cast, spleen hyperplasia [+]
View all ortholog results at Monarch