| Monarch Ortholog Phenotypes
|
Human (51 sources):
Abnormal CD4:CD8 ratio,
Abnormal facial shape,
Abnormality of humoral immunity,
Acute otitis media,
Agammaglobulinemia,
Autoimmune hemolytic anemia,
Autoimmune thrombocytopenia,
Autoimmunity,
Biliary tract abnormality,
Cholangitis,
Chronic hepatitis due to cryptosporidium infection,
Chronic lymphocytic meningitis,
Chronic mucocutaneous candidiasis,
Colitis,
Cutaneous anergy,
Decreased circulating antibody level,
Decreased circulating beta-2-microglobulin level,
Decreased lymphocyte proliferation in response to mitogen,
Decreased proportion of CD4-positive helper T cells,
Diarrhea,
Dysarthria,
Failure to thrive,
Gait ataxia,
Infectious encephalitis,
Lack of T cell function,
Malabsorption,
Neutropenia,
Neutropenia in presence of anti-neutropil antibodies,
Pancytopenia,
Panhypogammaglobulinemia,
Protracted diarrhea,
Recurrent Staphylococcus aureus infections,
Recurrent bacterial infections,
Recurrent candida infections,
Recurrent fungal infections,
Recurrent herpes,
Recurrent infection of the gastrointestinal tract,
Recurrent lower respiratory tract infections,
Recurrent protozoan infections,
Recurrent respiratory infections,
Recurrent upper respiratory tract infections,
Recurrent urinary tract infections,
Recurrent viral infections,
Reduced MHC II surface expression,
Rhinitis,
Sclerosing cholangitis,
Sinusitis,
Skin rash,
T lymphocytopenia,
Villous atrophy,
Viral hepatitis
[+]
|
|
Mouse (3 sources):
decreased grip strength,
decreased mean corpuscular hemoglobin,
decreased startle reflex
|
View all ortholog results at Monarch
|
These phenotypes are associated with this gene with a has phenotype relation via Monarch.