| Monarch Ortholog Phenotypes
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Human (14 sources):
Ataxia,
Central hypothyroidism,
Cerebellar hypoplasia,
Dysarthria,
Dystonia,
Failure to thrive,
Hypoglycemia,
Hypogonadism,
Intellectual disability,
Intellectual disability, moderate,
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Mouse (28 sources):
abnormal adipose tissue amount,
abnormal bone mineralization,
abnormal ductus venosus valve morphology,
abnormal estrous cycle,
abnormal hypothalamus secretion,
abnormal lean body mass,
blood in lymph vessels,
decreased bone mineral content,
decreased corpora lutea number,
decreased lean body mass,
decreased ovary weight,
decreased ovulation rate,
decreased testis weight,
delayed estrous cycle,
delayed vaginal opening,
embryo tumor,
homeostasis/metabolism phenotype,
increased exploration in new environment,
increased total body fat amount,
multiple persisting craniopharyngeal ducts,
no abnormal phenotype detected,
prenatal lethality, complete penetrance,
preweaning lethality, complete penetrance,
reduced female fertility,
reduced fertility,
reduced male fertility,
short perineum,
short proestrus
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.