st14 Phenotypes

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Phenotypes

Gene Literature (13)

Nucleotides (255)

Interactants (156)

XB-GENEPAGE-1008783

Gene Symbol: st14 Gene Name: suppression of tumorigenicity 14

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: st14 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (13 sources): Blepharitis, Brittle hair, Congenital ichthyosiform erythroderma, Corneal opacity, Curly hair, Hyperkeratosis, Hypohidrosis, Ichthyosis, Photophobia, Pili torti, Sparse hair, obsolete Hypotrichosis, obsolete Sparse and thin eyebrow [+]
Mouse (53 sources): abnormal colon morphology, abnormal corneocyte morphology, abnormal embryo size, abnormal enterocyte morphology, abnormal enterocyte physiology, abnormal enterocyte proliferation, abnormal epidermis stratum corneum morphology, abnormal epidermis stratum granulosum morphology, abnormal hair follicle morphology, abnormal keratinocyte differentiation, abnormal large intestine crypts of Lieberkuhn morphology, abnormal limb bud morphology, abnormal liver size, abnormal pericardium morphology, abnormal piliary canal morphology, abnormal salivary gland physiology, abnormal skin appearance, abnormal snout morphology, abnormal stratum corneum lipid matrix formation, abnormal tongue epithelium morphology, abnormal vibrissa follicle morphology, absent digestive secretion, absent gastric milk in neonates, absent vibrissae, acanthosis, decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number, decreased CD4-positive, alpha beta T cell number, decreased body length, decreased body size, decreased double-positive T cell number, decreased hair follicle number, decreased regulatory T cell number, decreased salivation, digestive/alimentary phenotype, enlarged corneocyte envelope, immune system phenotype, impaired skin barrier function, impaired stratum corneum desquamation, increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number, increased anti-nuclear antigen antibody level, increased autoantibody level, increased effector memory CD4-positive, alpha-beta T cell number, increased effector memory CD8-positive, alpha-beta T cell number, increased thymocyte apoptosis, lacrimal gland inflammation, megacolon, neonatal lethality, complete penetrance, postnatal lethality, complete penetrance, premature death, shiny skin, skin fibrosis, submandibular gland inflammation, underdeveloped hair follicles [+]
View all ortholog results at Monarch