| Monarch Ortholog Phenotypes
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Human (29 sources):
Abnormal foot morphology,
Abnormality of the dentition,
Astigmatism,
Broad-based gait,
Cerebral visual impairment,
Delayed ability to walk,
Delayed speech and language development,
Dysarthria,
Epicanthus,
Frontal bossing,
Generalized hypotonia,
Global developmental delay,
High, narrow palate,
Hypermetropia,
Hypertelorism,
Ischemic stroke,
Low-set ears,
Macrocephaly,
Midface retrusion,
Motor stereotypy,
Prominent forehead,
Prominent nose,
Scoliosis,
Speech apraxia,
Strabismus,
Stuttering,
Unsteady gait,
Ventriculomegaly,
Wide nasal bridge
[+]
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Mouse (7 sources):
abnormal bone mineralization,
abnormal locomotor activation,
abnormal locomotor behavior,
cardiovascular system phenotype,
embryonic lethality, incomplete penetrance,
increased bone mineral content,
reproductive system phenotype
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.