Monarch Ortholog Phenotypes
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Mouse (35 sources):
abnormal CNS synaptic transmission,
abnormal bone mineralization,
abnormal circulating iron level,
abnormal cochlear inner hair cell physiology,
abnormal dendritic spine morphology,
abnormal ear morphology,
abnormal hemoglobin content,
abnormal inner hair cell synaptic ribbon morphology,
abnormal locomotor activation,
abnormal mean corpuscular hemoglobin,
abnormal mean corpuscular volume,
abnormal miniature excitatory postsynaptic currents,
abnormal miniature inhibitory postsynaptic currents,
abnormal prepulse inhibition,
abnormal startle reflex,
decreased CNS synapse formation,
decreased anxiety-related response,
decreased cochlear outer hair cell number,
decreased locomotor activity,
decreased prepulse inhibition,
decreased pulmonary respiratory rate,
decreased startle reflex,
decreased thigmotaxis,
head tilt,
impaired righting response,
impaired swimming,
increased bone mineral content,
increased circulating iron level,
increased heart weight,
increased lean body mass,
increased mean corpuscular hemoglobin,
increased or absent threshold for auditory brainstem response,
limb grasping,
nervous system phenotype,
trunk curl
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