| Monarch Ortholog Phenotypes
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Human (19 sources):
Abnormal urine sodium concentration,
Abnormality of circulating cortisol level,
Decreased circulating renin level,
Failure to thrive,
Growth delay,
Hypertension,
Hypertensive retinopathy,
Hypokalemia,
Hypokalemic metabolic alkalosis,
Intrauterine growth retardation,
[+]
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Mouse (10 sources):
abnormal fetal cardiomyocyte proliferation,
abnormal kidney morphology,
abnormal suckling behavior,
decreased urine creatinine level,
decreased urine sodium level,
dilated distal convoluted tubule,
increased heart weight,
postnatal lethality, incomplete penetrance,
premature death,
weakness
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.