phc1 Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (321)

Interactants (24)

XB-GENEPAGE-1013247

Gene Symbol: phc1 Gene Name: polyhomeotic homolog 1

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (17 sources): Abnormal cortical bone morphology, Agenesis of corpus callosum, Global developmental delay, Gray matter heterotopia, Growth delay, Hyperreflexia, Hypoplasia of the frontal lobes, Intellectual disability, severe, Microcephaly, Pachygyria, Short stature, Sloping forehead, Thin upper lip vermilion, Unilateral renal agenesis, Upslanted palpebral fissure, Ventriculomegaly, Vesicoureteral reflux [+]
Mouse (34 sources): abnormal M line morphology, abnormal Z line morphology, abnormal atrial thrombosis, abnormal bulbus cordis morphology, abnormal cardiac outflow tract development, abnormal cardiovascular development, abnormal heart looping, abnormal heart right ventricle outflow tract morphology, abnormal hematopoietic stem cell morphology, abnormal mitochondrial crista morphology, abnormal myocardial fiber morphology, abnormal occipital bone morphology, abnormal optic cup morphology, abnormal presphenoid bone morphology, abnormal sarcomere morphology, abnormal semilunar valve morphology, abnormal sphenoid bone morphology, abnormal sternum morphology, cervical vertebral transformation, decreased body size, decreased spleen weight, decreased thymus weight, decreased ventricle muscle contractility, dilated heart ventricle, impaired hematopoiesis, increased cardiomyocyte apoptosis, lumbar vertebral transformation, palatal shelves fail to meet at midline, perinatal lethality, complete penetrance, premature death, pulmonary trunk hypoplasia, small occipital bone, thin myocardium, thin ventricular wall [+]
View all ortholog results at Monarch