myod1 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (502)

XB-GENEPAGE-1017497

Gene Symbol: myod1 Gene Name: myogenic differentiation 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormally irregular spatial pattern of somite (4 sources), increased size of the hypaxial muscle (3 sources), abnormal myocyte morphology (2 sources), abnormal somite morphology (2 sources), absent pronephric tubule (2 sources), increased size of the myotome (2 sources), abnormal nucleus morphology (1 source), abnormal presomitic mesoderm morphology (1 source), abnormally anteriorly mislocalised somite (1 source), abnormally localised myocyte (1 source), abnormally localised nucleus (1 source), decreased size of the myocyte (1 source), decreased size of the presomitic mesoderm (1 source)

Anatomical Phenotypes

Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.

abnormally irregular spatial pattern of somite (4 sources), increased size of the hypaxial muscle (3 sources), abnormal myocyte morphology (2 sources), abnormal somite morphology (2 sources), absent pronephric tubule (2 sources), increased size of the myotome (2 sources), abnormal nucleus morphology (1 source), abnormal presomitic mesoderm morphology (1 source), abnormally anteriorly mislocalised somite (1 source), abnormally localised myocyte (1 source), abnormally localised nucleus (1 source), decreased size of the myocyte (1 source), decreased size of the presomitic mesoderm (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: myod1 manipulated (19 sources), myod1 assayed (31 sources)
Computed annotations: myod1 assayed (16 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + myod1 MO (16 sources), Xla Wt + myod1 (6 sources), Xla Wt + Dre.lbx1 + myod1 (4 sources), Xla Wt + myod1 (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (53 sources): Abnormal abdomen morphology, Abnormality of pelvic girdle bone morphology, Absent palmar crease, Absent septum pellucidum, Akinesia, Arthrogryposis multiplex congenita, Blepharophimosis, Bradykinesia, Camptodactyly of finger, Cavum septum pellucidum, Cerebellar hypoplasia, Cleft palate, Cryptorchidism, Cystic hygroma, Dandy-Walker malformation, Depressed nasal bridge, Depressed nasal tip, Elbow ankylosis, Excessive daytime somnolence, Fetal akinesia sequence, Generalized amyotrophy, High palate, High, narrow palate, Hydrocephalus, Hypertelorism, Intestinal hypoplasia, Intrauterine growth retardation, Long philtrum, Micrognathia, Multiple joint contractures, Narrow mouth, Polyhydramnios, Posteriorly rotated ears, Premature birth, Proptosis, Pterygium, Ptosis, Pulmonary hypoplasia, Respiratory insufficiency, Rocker bottom foot, Scoliosis, Short neck, Short palpebral fissure, Short umbilical cord, Slender long bone, Small for gestational age, Small placenta, Talipes equinovarus, Telecanthus, Thin ribs, Thoracic hypoplasia, Ulnar deviation of the hand, Ulnar deviation of the hand or of fingers of the hand [+]
Mouse (6 sources): abnormal muscle development, abnormal myogenesis, abnormal skeletal muscle regeneration, decreased physiological sensitivity to xenobiotic, increased satellite cell number, no abnormal phenotype detected
View all ortholog results at Monarch