| Monarch Ortholog Phenotypes
|
Human (36 sources):
Abnormal inflammatory response,
Abnormality of bone marrow cell morphology,
Acne,
Anemia of inadequate production,
Arthralgia,
Bone pain,
Cachexia,
Congenital hypoplastic anemia,
Cough,
Edema,
Failure to thrive,
Fever,
Flexion contracture,
Glomerulopathy,
Growth delay,
Headache,
Hepatomegaly,
Hypochromic microcytic anemia,
Increased bone mineral density,
Increased susceptibility to fractures,
Inflammatory abnormality of the skin,
Leukocytosis,
Malabsorption,
Metaphyseal irregularity,
Microcytic anemia,
Microscopic hematuria,
Myalgia,
Osteomyelitis,
Papule,
Proteinuria,
Pulmonary infiltrates,
Pustule,
Recurrent fever,
Splenomegaly,
Synovitis,
Weight loss
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Mouse (15 sources):
abnormal cerebellar Purkinje cell layer,
abnormal gonadal fat pad morphology,
abnormal mean corpuscular hemoglobin,
decreased circulating free fatty acids level,
decreased fasting circulating glucose level,
decreased hemoglobin content,
decreased mean corpuscular hemoglobin,
decreased mean corpuscular hemoglobin concentration,
enlarged lymph nodes,
hydrometra,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.