|
XB-GENEPAGE-1033685
ccdc88c coiled-coil domain containing 88C
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
|
|---|
| obsolete duplicated anterior-posterior axis (11 sources), decreased length of anterior-posterior axis (8 sources), abnormal bending of dorsal trunk (7 sources), abnormal gastrulation (5 sources), abnormal bending of tail (4 sources), wholly anteriorized embryo (3 sources), abnormal incomplete closing of the neural tube (2 sources), decreased length of dorsal-ventral axis (2 sources), decreased length of whole organism (2 sources), decreased size of the head (2 sources), abnormally localised muscle (1 source), decreased size of the tail (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
|
|---|
| Computed annotations: ccdc88c assayed (3 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
|
|---|
| Xla Wt + ccdc88c (4 sources), Xla Wt + ccdc88c (2 sources), Xla Wt + ccdc88cdel_1-1151 (2 sources), Xla Wt + ccdc88cdel_1-1229 (2 sources), Xla Wt + ccdc88cdel_1301-1559 (2 sources), Xla Wt + ccdc88cdel_772-1261 (2 sources), Xla Wt + ccdc88c + dvl1 (1 source), Xla Wt + ccdc88c + dvl1 (1 source), Xla Wt + ccdc88c + dvl1 (1 source), Xla Wt + ccdc88c MO (1 source), Xla Wt + ctnnb1 + ccdc88c MO (1 source), Xla Wt + dvl1 + myc-Mmu.ccdc88c (1 source), Xla Wt + myc-Mmu.ccdc88c (1 source), Xla Wt + myc-Mmu.ccdc88c (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
|
|---|
| Human (18 sources): Abnormal speech pattern, Broad-based gait, Dysarthria, Dysdiadochokinesis, Dysmetria, Functional motor deficit, Gait ataxia, Hydrocephalus, Hyperreflexia, Intellectual disability, [+] |
| Mouse (3 sources): abnormal brain ependyma morphology, abnormal brain ependyma motile cilium location or orientation, impaired wound healing |
|
View all ortholog results at Monarch |