gtf2i Phenotypes

Phenotypes

XB-GENEPAGE-1217436

Gene Symbol: gtf2i Gene Name: general transcription factor IIi

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gtf2i assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (26 sources): abnormal brain development, abnormal craniofacial morphology, abnormal embryo development, absent embryonic epiblast, behavior/neurological phenotype, decreased body size, decreased embryo size, decreased embryonic epiblast cell proliferation, decreased exploration in new environment, decreased vertical activity, dilated allantois, distended pericardium, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, embryonic lethality, complete penetrance, embryonic lethality, incomplete penetrance, failure of chorioallantoic fusion, failure of heart looping, increased anxiety-related response, narrow head, nervous system phenotype, no abnormal phenotype detected, pharyngeal arch hypoplasia, prenatal lethality, incomplete penetrance, reduced female fertility, reduced male fertility [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (26 sources): abnormal brain development, abnormal craniofacial morphology, abnormal embryo development, absent embryonic epiblast, behavior/neurological phenotype, decreased body size, decreased embryo size, decreased embryonic epiblast cell proliferation, decreased exploration in new environment, decreased vertical activity, [+]