tbx21 Phenotypes

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Phenotypes

XB-GENEPAGE-479102

Gene Symbol: tbx21 Gene Name: T-box 21

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (3 sources): Aspirin-induced asthma, Asthma, Nasal polyposis
Mouse (33 sources): CNS inflammation, abnormal CD4-positive T cell differentiation, abnormal CD4-positive, alpha-beta T cell physiology, abnormal CD8-positive, alpha-beta cytotoxic T cell morphology, abnormal NK cell differentiation, abnormal T-helper 1 cell differentiation, abnormal T-helper 1 cell morphology, abnormal cytokine level, abnormal interleukin level, abnormal leukocyte migration, abnormal tumor necrosis factor level, absent NK T cells, decreased CD4-positive, alpha beta T cell number, decreased NK T cell number, decreased T helper 1 cell number, decreased interferon-gamma secretion, decreased memory T cell number, decreased susceptibility to experimental autoimmune encephalomyelitis, immune system phenotype, impaired natural killer cell mediated cytotoxicity, increased CD8-positive, alpha-beta T cell number, increased NK cell number, increased T-helper 2 cell number, increased airway responsiveness, increased effector memory CD8-positive, alpha-beta T cell number, increased interleukin-17 secretion, increased interleukin-2 secretion, increased natural killer cell mediated cytotoxicity, increased susceptibility to Riboviria infection, increased susceptibility to induced colitis, increased susceptibility to parasitic infection, increased tumor necrosis factor secretion, respiratory system inflammation [+]
View all ortholog results at Monarch