| Monarch Ortholog Phenotypes
|
|
Human (1 source):
Macular coloboma
|
Mouse (22 sources):
abnormal lens development,
abnormal optic cup morphology,
abnormal optic vesicle formation,
abnormal placental labyrinth vasculature morphology,
abnormal retina apoptosis,
abnormal retina layer morphology,
abnormal vascular regression,
abnormal visceral yolk sac morphology,
abnormal vitelline vascular remodeling,
decreased body size,
disorganized retina ganglion layer,
disorganized yolk sac vascular plexus,
ectopic Paneth cells,
hydrometra,
increased retina apoptosis,
increased total retina thickness,
pale yolk sac,
prenatal lethality, complete penetrance,
preweaning lethality, complete penetrance,
small superior vagus ganglion,
vision/eye phenotype,
vitreous body deposition
[+]
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.