abnormal heart echocardiography feature, abnormal hepatocyte morphology, abnormal lens development, abnormal lens epithelium morphology, abnormal limb bud morphology, abnormal limb morphology, abnormal liver development, abnormal liver size, abnormal mammary gland development, abnormal mammary gland epithelium morphology, abnormal midbrain development, abnormal myocardial fiber morphology, abnormal neuron apoptosis, abnormal placenta labyrinth morphology, abnormal placenta vasculature, abnormal placental labyrinth vasculature morphology, abnormal spongiotrophoblast layer morphology, abnormal telencephalon development, abnormal trophoblast giant cell morphology, abnormal vascular endothelial cell development, absent megakaryocytes, cardiac edema, cardiac interstitial fibrosis, decreased body size, decreased cardiac muscle contractility, decreased circulating thyroxine level, decreased embryo size, decreased fibroblast proliferation, decreased mammary gland epithelial cell proliferation, decreased mitochondrial DNA content, decreased thyroid-stimulating hormone level, dilated heart atrium, dilated heart ventricle, dilated liver sinusoidal spaces, embryonic growth retardation, embryonic lethality between somite formation and embryo turning, incomplete penetrance, embryonic lethality during organogenesis, complete penetrance, embryonic lethality prior to tooth bud stage, embryonic lethality, complete penetrance, hydrometra, impaired placental function, increased angiogenesis, increased cardiomyocyte apoptosis, increased erythrocyte cell number, increased nucleated erythrocyte cell number, increased vascular permeability, myocardial trabeculae hypoplasia, myocardium hypoplasia, premature death, small superior vagus ganglion, thin myocardium, thin myocardium compact layer, thin ventricular wall, trabecula carnea hypoplasia, ventricular hypoplasia