agt Phenotypes

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Phenotypes

Gene Literature (8)

Nucleotides (150)

Interactants (93)

XB-GENEPAGE-480137

Gene Symbol: agt Gene Name: angiotensinogen

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: agt assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (10 sources): Abnormality of the urinary system, Anuria, Hypotension, Microcephaly, Oligohydramnios, Potter facies, Pulmonary hypoplasia, Renotubular dysgenesis, Respiratory insufficiency, Widely patent fontanelles and sutures
Mouse (51 sources): abnormal blood homeostasis, abnormal blood-brain barrier function, abnormal enzyme/coenzyme level, abnormal hippocampus granule cell layer, abnormal juxtaglomerular apparatus morphology, abnormal kidney afferent arteriole morphology, abnormal kidney blood vessel morphology, abnormal kidney cortex artery morphology, abnormal kidney inner medulla morphology, abnormal kidney interlobular artery morphology, abnormal kidney morphology, abnormal postnatal growth/weight/body size, abnormal renal filtration rate, abnormal renal glomerulus morphology, adipose tissue phenotype, cardiovascular system phenotype, decreased body size, decreased circulating angiotensinogen level, decreased epididymal fat pad weight, decreased fat cell size, decreased heart weight, decreased liver weight, decreased ovulation rate, decreased renal glomerulus number, decreased systemic arterial blood pressure, decreased systemic arterial diastolic blood pressure, decreased systemic arterial systolic blood pressure, decreased urine aldosterone level, decreased urine osmolality, decreased urine sodium level, dilated kidney collecting duct, dilated renal tubules, growth/size/body region phenotype, homeostasis/metabolism phenotype, increased circulating angiotensinogen level, increased circulating antidiuretic hormone level, increased circulating creatinine level, increased fluid intake, increased kidney weight, increased renal plasma flow rate, increased systemic arterial blood pressure, increased urine antidiuretic hormone level, increased urine flow rate, kidney medulla atrophy, kidney papillary atrophy, kidney papillary hypoplasia, postnatal lethality, incomplete penetrance, renal/urinary system phenotype, reproductive system phenotype, slow postnatal weight gain, vascular smooth muscle hyperplasia [+]
View all ortholog results at Monarch