Monarch Ortholog Phenotypes
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Mouse (39 sources):
abnormal circulating ketone body level,
abnormal coat appearance,
abnormal epidermis stratum corneum morphology,
abnormal hepatocyte morphology,
abnormal keratinocyte differentiation,
abnormal lipid level,
abnormal myocardial fiber morphology,
abnormal myocardial fiber physiology,
abnormal myocardium layer morphology,
abnormal skin coloration,
abnormal vascular endothelial cell morphology,
cardiac fibrosis,
cardiac hypertrophy,
decreased abdominal adipose tissue amount,
decreased cardiac cell glucose uptake,
decreased circulating glucose level,
decreased fatty acid oxidation,
decreased keratohyalin granule number,
decreased liver glycogen level,
decreased muscle cell glucose uptake,
decreased susceptibility to diet-induced obesity,
decreased systemic arterial systolic blood pressure,
decreased ventricle muscle contractility,
delayed wound healing,
heart inflammation,
impaired adaptive thermogenesis,
improved glucose tolerance,
increased circulating glucose level,
increased fatty acids level,
increased gonadal fat pad weight,
increased insulin sensitivity,
increased muscle cell glucose uptake,
increased sensitivity to induced morbidity/mortality,
increased susceptibility to diet-induced obesity,
increased triglyceride level,
integument phenotype,
myocardial fiber degeneration,
renal/urinary system phenotype,
thin epidermis stratum granulosum
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