|
XB-GENEPAGE-480319
hspb1 heat shock protein family B (small) member 1
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
|
|---|
| abnormal development of eye (1 source), abnormal development of lens (1 source), abnormal eye morphology (1 source), abnormal lens (1 source), abnormal lens fiber cell mass (1 source), decreased size of the lens (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
|
|---|
| Computed annotations: hspb1 assayed (3 sources) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
|
|---|
| cataract 36 (1AP source) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
|
|---|
| Xtr Wt + hspb1 MO (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
|
|---|
| Human (32 sources): Areflexia, Areflexia of lower limbs, Chronic axonal neuropathy, Decreased motor nerve conduction velocity, Difficulty walking, Distal amyotrophy, Distal lower limb amyotrophy, Distal lower limb muscle weakness, Distal muscle weakness, Distal sensory impairment, [+] |
| Mouse (11 sources): abnormal RR interval, abnormal heart rate, abnormal macrophage physiology, abnormal wound healing, decreased fibroblast proliferation, delayed wound healing, impaired wound healing, increased body length, increased interleukin-6 secretion, no abnormal phenotype detected, [+] |
|
View all ortholog results at Monarch |