| Monarch Ortholog Phenotypes
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Human (9 sources):
Abnormal intestine morphology,
Autoimmune hemolytic anemia,
Decreased proportion of CD8-positive T cells,
Eczematoid dermatitis,
Failure to thrive,
Immunodeficiency,
Recurrent gastroenteritis,
Recurrent otitis media,
Recurrent respiratory infections
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Mouse (9 sources):
abnormal CD8-positive, alpha-beta T cell physiology,
abnormal T cell activation,
abnormal T cell differentiation,
abnormal T cell proliferation,
abnormal response to infection,
decreased cytotoxic T cell cytolysis,
decreased thymocyte number,
immune system phenotype,
increased T cell apoptosis
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.