tjp2 Phenotypes

XB-GENEPAGE-480466

Gene Symbol: tjp2 Gene Name: tight junction protein 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tjp2 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (13 sources): Abnormality of refraction, Failure to thrive, Fat malabsorption, Hepatic failure, Hepatocellular carcinoma, Increased serum bile acid concentration, Intrahepatic cholestasis, Low levels of vitamin K, Myopia, Portal hypertension, Pruritus, Rickets, Steatorrhea [+]
Mouse (9 sources): abnormal plasma membrane morphology, absent mesoderm, decreased cell proliferation, decreased embryo size, disorganized embryonic tissue, embryonic growth arrest, embryonic lethality between implantation and somite formation, complete penetrance, failure to gastrulate, increased embryonic tissue cell apoptosis
View all ortholog results at Monarch