cdh5 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-480936

Gene Symbol: cdh5 Gene Name: cadherin 5

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cdh5 assayed (1 source)
Computed annotations: cdh5 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (57 sources): abnormal angiogenesis, abnormal cardiac outflow tract development, abnormal cell death, abnormal cellular extravasation, abnormal common myeloid progenitor cell morphology, abnormal definitive hematopoiesis, abnormal hematopoietic precursor cell number, abnormal hematopoietic stem cell physiology, abnormal intersomitic vessel morphology, abnormal leukocyte migration, abnormal lymphatic vessel endothelial cell morphology, abnormal lymphatic vessel endothelium morphology, abnormal placenta vasculature, abnormal retina vasculature morphology, abnormal somite development, abnormal umbilical artery morphology, abnormal umbilical cord blood vessel morphology, abnormal uterus morphology, abnormal vascular development, abnormal vascular endothelial cell development, abnormal vascular endothelial cell morphology, abnormal vascular permeability, abnormal vasculogenesis, abnormal vein development, abnormal visceral yolk sac blood island morphology, abnormal vitelline vasculature morphology, absent vitelline blood vessels, cardiovascular system phenotype, decreased angiogenesis, decreased liver weight, delayed heart development, dilated dorsal aorta, distended pericardium, embryonic growth arrest, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, embryonic lethality, complete penetrance, enlarged endometrial glands, hematopoietic system phenotype, immune system phenotype, incomplete embryo turning, incomplete somite formation, increased apoptosis, increased neutrophil cell number, increased vascular permeability, lethality throughout fetal growth and development, complete penetrance, liver hypoplasia, liver/biliary system phenotype, no abnormal phenotype detected, ovarian follicular cyst, ovary fibrosis, preweaning lethality, incomplete penetrance, small liver, small pharyngeal arch, uterus fibrosis, uterus hypertrophy [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (57 sources): abnormal angiogenesis, abnormal cardiac outflow tract development, abnormal cell death, abnormal cellular extravasation, abnormal common myeloid progenitor cell morphology, abnormal definitive hematopoiesis, abnormal hematopoietic precursor cell number, abnormal hematopoietic stem cell physiology, abnormal intersomitic vessel morphology, abnormal leukocyte migration, [+]