abnormal myelopoiesis, abnormal spleen white pulp morphology, arrested B cell differentiation, decreased bone marrow cell number, decreased circulating interferon-alpha level, decreased circulating interferon-gamma level, decreased circulating interleukin-12 level, decreased dendritic cell number, decreased erythrocyte cell number, decreased hemoglobin content, decreased interferon-alpha secretion, decreased interferon-gamma secretion, decreased interleukin-12 secretion, decreased mature B cell number, decreased plasmacytoid dendritic cell number, decreased pre-B cell number, decreased pro-B cell number, decreased splenocyte number, delayed cellular replicative senescence, increased B cell derived lymphoma incidence, increased bone marrow cell number, increased circulating interleukin-6 level, increased circulating tumor necrosis factor level, increased dendritic cell number, increased granulocyte number, increased hematopoietic stem cell number, increased histiocytic sarcoma incidence, increased neutrophil cell number, increased pre-pro B cell number, increased pro-B cell number, increased spleen red pulp amount, increased spleen white pulp amount, increased susceptibility to Herpesvirales infection, increased susceptibility to Herpesvirales infection induced morbidity/mortality, increased susceptibility to Riboviria infection, intermingled spleen red and white pulp, myeloid hyperplasia, premature death, small lymph nodes