sox18 Phenotypes

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Phenotypes

Gene Literature (14)

Nucleotides (71)

Interactants (290)

XB-GENEPAGE-483232

Gene Symbol: sox18 Gene Name: SRY-box 18

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sox18 assayed (14 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (43 sources): Abnormal renal glomerulus morphology, Abnormality of the dentition, Abnormality of the lymphatic system, Abnormality of the nail, Absent eyebrow, Absent eyelashes, Ascites, Chronic kidney disease, Cutis marmorata, Dermal atrophy, Epicanthus, Facial telangiectasia in butterfly midface distribution, Freckling, Global developmental delay, Hydrocele testis, Hydrops fetalis, Hyperkeratosis, Long nose, Lymphedema, Mandibular prognathia, Membranoproliferative glomerulonephritis, Nonimmune hydrops fetalis, Oval face, Palmar telangiectasia, Palpebral edema, Plantar telangiectasia, Pleural effusion, Predominantly lower limb lymphedema, Prominent nasal bridge, Pulmonary lymphangiectasia, Reduced subcutaneous adipose tissue, Renal insufficiency, Sparse and thin eyebrow, Sparse body hair, Sparse eyelashes, Sparse hair, Sparse scalp hair, Telangiectasia of extensor surfaces, Thick vermilion border, Thin skin, Toenail dysplasia, Wide nasal bridge, obsolete Hypotrichosis [+]
Mouse (34 sources): abnormal awl hair morphology, abnormal blood urea nitrogen level, abnormal hair follicle morphology, abnormal pericyte morphology, abnormal vascular endothelial cell physiology, abnormal vibrissa morphology, abnormal vibrissa number, abnormal zigzag hair morphology, absent auchene hairs, cardiovascular system phenotype, darkened coat color, decreased blood urea nitrogen level, decreased body size, decreased thigmotaxis, decreased zigzag hair amount, delayed hair appearance, disheveled coat, embryonic lethality, complete penetrance, embryonic lethality, incomplete penetrance, hematoma, increased mean corpuscular hemoglobin, increased vascular endothelial cell number, intestinal fibrosis, lethality throughout fetal growth and development, complete penetrance, neonatal lethality, complete penetrance, neonatal lethality, incomplete penetrance, no abnormal phenotype detected, perinatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, preweaning lethality, incomplete penetrance, retarded hair growth, short vibrissae, skin edema [+]
View all ortholog results at Monarch