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Summary Expression Phenotypes Gene Literature (53) GO Terms (18) Nucleotides (488) Proteins (48) Interactants (914) Wiki
XB-GENEPAGE-483417

sox11     SRY-box 11

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal eye (1 source), abnormal eye morphology (1 source), decreased size of the head (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: sox11 manipulated (4 sources), sox11 assayed (29 sources)
Computed annotations: sox11 assayed (14 sources)
Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
Coffin-Siris syndrome (1AP source)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + Sox11 (2 sources), sox11 MO KD (1 source), Xla Wt + sox11 (1 source), Xla Wt + Sox11 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (80 sources): Abnormal clavicle morphology, Abnormal facial shape, Abnormal hip bone morphology, Abnormal intervertebral disk morphology, Abnormality of cardiovascular system morphology, Abnormality of the columella, Abnormality of the dentition, Abnormality of the nares, Aplasia/Hypoplasia of the cerebellum, Aplasia/Hypoplasia of the distal phalanx of the 5th finger, [+]
Mouse (58 sources): abnormal axon fasciculation, abnormal bone mineralization, abnormal bronchus morphology, abnormal caudal vertebrae morphology, abnormal cerebral cortex morphology, abnormal cortical ventricular zone morphology, abnormal craniofacial morphology, abnormal cranium morphology, abnormal dentate gyrus morphology, abnormal embryonic/fetal subventricular zone morphology, [+]

View all ortholog results at Monarch