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Summary Expression Phenotypes Gene Literature (12) GO Terms (7) Nucleotides (314) Proteins (38) Interactants (229) Wiki

rab7a     RAB7A, member RAS oncogene family

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: rab7a assayed (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (20 sources): Areflexia, Autoamputation, Autoamputation of foot, Axonal degeneration/regeneration, Decreased motor nerve conduction velocity, Decreased number of peripheral myelinated nerve fibers, Distal amyotrophy, Distal muscle weakness, Dystrophic toenail, Foot dorsiflexor weakness, [+]
Mouse (12 sources): abnormal T cell subpopulation ratio, abnormal autophagy, abnormal primitive streak elongation, abnormal visceral endoderm morphology, decreased CD4-positive, alpha beta T cell number, decreased T cell proliferation, embryonic lethality, failure to gastrulate, increased mitochondrial size, lethality, incomplete penetrance, [+]

View all ortholog results at Monarch