rab7a RAB7A, member RAS oncogene family
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
|Computed annotations: rab7a assayed (1 source)|
|Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (20 sources):
Autoamputation of foot,
Decreased motor nerve conduction velocity,
Decreased number of peripheral myelinated nerve fibers,
Distal muscle weakness,
Foot dorsiflexor weakness,
Foot osteomyelitis, Hammertoe, Hyporeflexia, Peripheral axonal atrophy, Peripheral neuropathy, Pes cavus, Pes planus, Sensory neuropathy, Somatic sensory dysfunction, Steppage gait[+]
|Mouse (12 sources): abnormal T cell subpopulation ratio, abnormal autophagy, abnormal primitive streak elongation, abnormal visceral endoderm morphology, decreased CD4-positive, alpha beta T cell number, decreased T cell proliferation, embryonic lethality, failure to gastrulate, increased mitochondrial size, lethality, incomplete penetrance, [+]|
View all ortholog results at Monarch