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Summary Expression Phenotypes Gene Literature (261) GO Terms (7) Nucleotides (120) Proteins (54) Interactants (309) Wiki
XB-GENEPAGE-483702

pomc     proopiomelanocortin

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pomc assayed (5 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (22 sources): Acanthosis nigricans, Adrenal hypoplasia, Adrenal insufficiency, Adrenocorticotropic hormone deficiency, Central adrenal insufficiency, Childhood-onset truncal obesity, Cholestasis, Decreased response to growth hormone stimulation test, Delayed puberty, Delayed skeletal maturation, [+]
Mouse (53 sources): abnormal adrenal gland zona fasciculata morphology, abnormal alcohol consumption, abnormal behavioral response to addictive substance, abnormal corticosterone level, abnormal neuron physiology, abnormal operant conditioning behavior, abnormal response/metabolism to endogenous compounds, abnormal touch/ nociception, absent adrenal gland, adipose tissue phenotype, [+]

View all ortholog results at Monarch