Downslanted palpebral fissures, Feeding difficulties, Ganglioneuroblastoma, Ganglioneuroma, Hypercapnia, Hyperhidrosis, Hypotonia, Hypoventilation, Hypoxemia, Low-set ears, Neoplasm of the central nervous system, Neuroblastoma, Posteriorly rotated ears, Respiratory insufficiency, Seizure

abnormal locus ceruleus morphology, abnormal metanephric mesenchyme morphology, abnormal motor neuron innervation pattern, abnormal muscle spindle morphology, abnormal myenteric nerve plexus morphology, abnormal neurotransmitter secretion, abnormal ovary topology, abnormal podocyte morphology, abnormal renal corpuscle morphology, abnormal renal tubule morphology, abnormal spinal cord lateral motor column morphology, abnormal spinal nerve morphology, abnormal spleen red pulp morphology, abnormal submucous nerve plexus morphology, abnormal substantia nigra morphology, abnormal superior cervical ganglion morphology, abnormal tegmentum morphology, abnormal ureteric bud invasion, abnormal ureteric bud morphology, abnormal ventral striatum morphology, absent enteric neurons, absent ureter, absent ureteric bud, cardiovascular system phenotype, decreased glomerular capillary number, decreased kidney weight, decreased locomotor activity, decreased motor neuron number, decreased podocyte number, decreased renal glomerulus number, distended duodenum, distended stomach, fused podocyte foot processes, growth/size/body region phenotype, impaired branching involved in ureteric bud morphogenesis, increased compensatory renal growth, increased kidney cell proliferation, increased kidney weight, increased mean systemic arterial blood pressure, increased mesangial cell number, increased renal glomerulus basement membrane thickness, megacolon, muscle phenotype, neonatal lethality, complete penetrance, preweaning lethality, incomplete penetrance, renal glomerulus hypertrophy, renal/urinary system phenotype, small dorsal root ganglion, small kidney