| Monarch Ortholog Phenotypes
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Human (5 sources):
Atrioventricular canal defect,
Dextrocardia,
Ectopia of the spleen,
Right aortic arch,
Ventricular septal defect
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Mouse (19 sources):
abnormal bronchus morphology,
abnormal cardiac outflow tract development,
abnormal direction of heart looping,
abnormal embryo size,
abnormal heart development,
abnormal heart position or orientation,
abnormal left-right axis patterning,
decreased startle reflex,
increased skeletal muscle weight,
increased thoracic vertebrae number,
lumbar vertebral transformation,
postnatal lethality, complete penetrance,
postnatal lethality, incomplete penetrance,
preweaning lethality, incomplete penetrance,
right pulmonary isomerism,
sacral vertebral transformation,
small spleen,
thoracic vertebral transformation,
vertebral transformation
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.