| Monarch Ortholog Phenotypes
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Human (15 sources):
Atrioventricular block,
Centrally nucleated skeletal muscle fibers,
Difficulty walking,
Elevated circulating creatine kinase concentration,
Exercise intolerance,
Limb muscle weakness,
Limb-girdle muscle weakness,
Loss of ability to walk,
Muscular dystrophy,
Myalgia,
[+]
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Mouse (10 sources):
abnormal response of heart to induced stress,
abnormal sinoatrial node conduction,
abnormal sinoatrial node morphology,
abnormal vocalization,
cardiovascular system phenotype,
impaired skeletal muscle regeneration,
improved glucose tolerance,
increased bone mineral content,
increased grip strength,
increased lean body mass
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.